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Angiography I Angiography refers to the radiographic examination of vessels after injection of a contrast medium. Because of the relative densities of the soft tissues of the body, contrast medium must be added to visualize the circulatory system. The circulatory system consists of the cardiovascular and lymphatic components. The cardiovascular portion includes the heart, blood, and vessels that transport the blood. The lymphatic element of the circulatory system is composed of a clear, watery fluid called lymph, along with lymphatic vessels and lymphatic nodes. The cardiovascular and lymphatic components differ in their function and method of transporting their respective fluids within the vessels. The cardiovascular, or blood circulatory, division may be divided further into the cardio (circulation within the heart) and vascular (blood vessel) components. The vascular or vessel component is divided into the pulmonary (heart to lungs and back) and the general, or systemic, systems (throughout the body) Functions of the cardiovascular system include the following: 1.Transportation of oxygen, nutrients, hormones, and chemicals necessary for normal body activity 2.Removal of waste products through the kidneys and lungs 3.Maintenance of body temperature and water and electrolyte balance. These functions are performed by the following blood components: red blood cells, white blood cells, and platelets suspended in plasma Blood Components: Red blood cells, or erythrocytes, are produced in the red marrow of certain bones and transport oxygen by the protein hemoglobin to body tissues. White blood cells, or leukocytes, are formed in bone marrow and lymph tissue and defend the body against infection and disease. Platelets, also originating from bone marrow, repair tears in blood vessel walls and promote blood clotting. Plasma, the liquid portion of the blood, consists of 92% water and about 7% plasma protein and salts, nutrients, and oxygen. Arteries Vessels that transport oxygenated blood from the heart to tissues are called arteries. Arteries that originate directly from the heart are large, but they subdivide and decrease in size as they extend from the heart to various parts of the body. The smaller arteries are termed arterioles. As the blood travels through the arterioles, it enters the tissues through the smallest subdivision of these vessels, known as capillaries Veins The deoxygenated blood returns to the heart through the venous system. The venous system extends from venous capillaries to venules to veins, increasing in size as it nears the heart. The elements of the blood vessel circuit (veins, venules, capillaries, arterioles, and arteries), which supply blood to the lungs and back, make up the pulmonary circulation component of the cardiovascular system. As previously noted, arteries generally carry oxygenated blood away from the heart to the capillaries. Exceptions to this are the pulmonary arteries, which carry deoxygenated blood to the lungs that has been returned to the heart through the superior and inferior venae cavae. The superior and inferior venae cavae (singular, vena cava) empty the returning deoxygenated blood into the right atrium of the heart. The heart pumps this deoxygenated blood from the right ventricle through the pulmonary arteries to the lungs, where oxygen and carbon dioxide are exchanged through the small air sacs or alveoli of the lungs. The oxygenated blood then returns through the pulmonary veins to the left atrium of the heart The heart itself is divided into four chambers: the right and left atria and the right and left ventricles. Each chamber functions to receive and/or pump blood. The blood circulation is a closed system by which unoxygenated blood enters the right atrium from all parts of the body, is reoxygenated in the lungs, and is returned to the body by the left ventricle. Blood returning to the heart enters the right atrium through the superior and inferior venae cavae. Blood in the superior vena cava originates from the head, chest, and upper limbs. The inferior vena cava serves to deliver blood into the right atrium from the abdomen and lower limbs http://www.youtube.com/watch?v=D3ZDJg FDdk0 CORONARY ARTERIES The coronary arteries are the vessels that deliver blood to the heart muscle. The two coronary arteries are called the right and the left. Both coronary arteries originate from the aortic bulb. The right coronary artery arises from the right (anterior) sinuses of the aortic bulb, and the left coronary artery originates from the left (posterior) aortic bulb sinus. The right coronary artery supplies much of the right atrium and the right ventricle of the heart. The left coronary artery supplies blood to both ventricles and the left atrium of the heart. Many interconnections or anastomoses exist between the left and right coronary arteries. Blood returns to the right atrium of the heart via the coronary veins The coronary sinus system returns blood to the right atrium for recirculation. The coronary sinus is a large vein on the posterior side of the heart between the atria and ventricles. BLOOD SUPPLY TO THE BRAIN The brain is supplied with blood by major arteries of the systemic circulation. The four major arteries that supply the brain are as follows : 1.Right common carotid artery 2.Left common carotid artery 3.Right vertebral artery 4.Left vertebral artery BRANCHES OF THE AORTIC ARCH The aorta is the major artery leaving the left ventricle of the heart. Three major branches arise from the arch of the aorta and include the following: 1.Brachiocephalic artery 2.Left common carotid artery 3.Left subclavian artery INTERNAL CAROTID ARTERY Each internal carotid artery ascends to enter the carotid canal in the petrous portion of the temporal bone. Within the petrous pyramid, the artery curves forward and medially. Before supplying the cerebral hemispheres, each internal carotid artery passes through a collection of venous channels around the sella turcica. Each internal carotid artery passes through the dura mater, medial to each anterior clinoid process, to bifurcate into the cerebral branches. The S-shaped portion of each internal carotid artery is termed the carotid siphon and is studied carefully by the radiologist. GREAT VEINS OF THE NECK The three pairs of major veins that drain the head, face, and neck region shown in include the following: 1.Right and left internal jugular veins 2.Right and left external jugular veins 3.Right and left vertebral veins THORACIC ARTERIES The aorta and pulmonary arteries are the major arteries located within the chest. The pulmonary arteries supply the lungs with deoxygenated blood The aorta extends from the heart to about the fourth lumbar vertebra and is divided into thoracic and abdominal sections. The thoracic section is subdivided into the following four segments 1.Aortic bulb (root) 2.Ascending aorta 3.Aortic arch 4.Descending aorta ABDOMINAL ARTERIES The abdominal aorta is the continuation of the thoracic aorta. The abdominal aorta is anterior to the vertebrae and extends from the diaphragm to approximately L4, where it bifurcates into the right and left common iliac arteries. Five major branches of the abdominal aorta exist that are of greatest interest in angiography. Any one of these branches may be selectively catheterized for study of a specific organ. Blood is returned from structures below the diaphragm (the trunk and lower limbs) to the right atrium of the heart by the inferior vena cava. Several radiographically important tributaries to the inferior vena cava exist. These veins include the right and left common iliacs, internal iliacs, external iliacs, renal veins and the hepatic portal system .The iliac veins drain the pelvic area and lower limbs, and the renal veins return blood from the kidneys. The hepatic portal system includes all veins that drain blood from the abdominal digestive tract and from the spleen, colon, and small intestine. From these organs, this blood is conveyed to the liver through the hepatic portal vein. While in the liver, this blood is “filtered” and is returned to the inferior vena cava by the hepatic veins. Several major tributaries to the hepatic veins exist . The splenic vein is a large vein with its own tributaries, which return blood from the spleen UPPER LIMB ARTERIES The arterial circulation of the upper limb is generally considered to begin at the subclavian artery. The origin of the subclavian artery differs from the right side to the left side. On the right side, the subclavian arises from the brachiocephalic artery, whereas the left subclavian originates directly from the aortic arch. The arterial circulation of the lower limb begins at the external iliac artery and ends at the veins of the foot The first artery to enter the lower limb is the common femoral artery. The common femoral artery divides into the femoral and deep femoral arteries. The femoral artery extends down the leg and becomes the popliteal artery at the level of the knee. Major branches of the popliteal are the anterior tibial and posterior tibial arteries LYMPH DRAINAGE The lymphatic system serves to drain interstitial fluid (fluid in the spaces between the cells) and return it to the venous system. The fluid from the left side of the body, the lower limbs, pelvis, and abdomen enters the venous system by the thoracic duct (largest lymph vessel in the body), which drains into the left subclavian vein near its junction with the left jugular vein FUNCTIONS Functions of the lymphatic portion of the circulatory system are as follows: 1.Fights disease by producing lymphocytes and macrophages 2.Returns proteins and other substances to the blood 3.Filters the lymph in the lymph nodes 4.Transfers fats from the intestine to the thoracic duct and hence to the blood ANGIOGRAPHIC PROCEDURES Overview As defined at the beginning of this chapter, angiography refers to radiologic imaging of blood vessels after injection of a contrast medium. To visualize these low-contrast structures, contrast media is injected by a catheter that is placed in the vessel of interest. Positive contrast media are more commonly used, but there are instances when use of negative contrast media is indicated. Highly specialized imaging equipment is required for these procedures. Angiography can be more specifically described as follows: •Arteriography: imaging of the arteries •Venography: imaging of the veins •Angiocardiography: imaging of the heart and associated structures •Lymphography: imaging of the lymphatic vessels/nodes