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Histology of the immune
(lymphoid, lymphatic) system questions
• Jeanne Adiwinata Pawitan
• Dept. of Histology
• FMUI
Jeanne A Pawitan
Lymph nodule
• Explain the microscopic appearance of a
lymph nodule/primary nodule
• In the lymph nodule, mention the place
where differentiation of b lymphocytes
occur! What cells can be found there, and
where are their location?
Jeanne A Pawitan
Thymus
• Explain the microscopic appearance of
the lobules in the thymus!
• Explain the blood supply of the thymus!
• What is blood thymus barrier? Mention
the structures/cells that plays a role in
blood thymus barrier!
• In thymus T cells proliferate and became
mature. What are the properties of
mature T cells?
Jeanne A Pawitan
Thymus
• What are the properties and functions of
epithelial reticular cells type I, II in
thymus?
• What plays a role in the maturation of T
cells?
Jeanne A Pawitan
Lymph node
• Mention the cells found in paracortex of
a lymph node! Where did the cells come
from, and where did they go to?
• What is high endothelial venules (HEVs)?
Where can you find HEV in lymph node?
What event happen here and why?
Jeanne A Pawitan
Lymph node - histophysiology
• Explain the function of lymph node as
lymph filter!
• Explain the role of lymph node in antigen
recognition!
• Explain the role of lymph node in Ab
formation and the prompt and potent
reaction after 2nd exposure to Ag!
Jeanne A Pawitan
Spleen
• Mention the cells that can be found in the
marginal zone of the spleen!
• What is marginal sinus in the spleen, and
explain its location and properties!
• Explain the events that happen in the
marginal zone of the spleen!
Jeanne A Pawitan
Tonsils
• Mention the location and explain the
microscopic structure of palatine tonsil!
• Mention the location and explain the
microscopic structure of pharyngeal
tonsil!
• Mention the location and explain the
microscopic structure of lingual tonsil!
• What can you find in the crypt of
palatine tonsil?
Jeanne A Pawitan