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How will Kim K know when she is in labor? What effect did estrogen have on Janelle’s uterus? What are benefits of breastfeeding? Lactation Physiology of lactation Changes during pregnancy Increased breast tissue Maturation of structure Hormonal controls Prolactin: stimulates milk production Oxytocin: stimulates milk release “let-down” reflex 4 SFCC: Figure 14.12 5 SFCC: Figure 14.14 7 Lactation and Breastfeeding Obstetrics and Gynecology Breastfeeding Infant Health Benefits COLOSTRUM Small amount for the immature digestive system ‘paints’ the digestive tract Low fat for easy digestion Contains mothers antibodies which boost infants’ immune system Acts as a laxative to ease passage of meconium Breastfeeding Infant Health Benefits The milk comes in Transitional milk for up to 2 weeks May still have yellow appearance Amounts increase quickly as infant hungers and digestive system matures Mature milk Supply/demand system engorgement decreases Breastfeeding Infant Health Benefits Lower risk of Diarrhea Constipation Infections Ear, respiratory, meningitis, urinary tract SIDS More Breastfeeding Infant Health Benefits Allergic diseases Chronic digestive diseases Juvenile onset diabetes Acute leukemia Adult obesity EVEN more Breastfeeding Infant Health Benefits Provides immunologic protection while the infant’s immune system is maturing Antimicrobial agents Anti-inflammatory agents Immunomodulating agents Breastfeeding Infant Health Benefits Preterm Infants Decreased necrotizing enterocolitis Decreased retinopathy of prematurity (ROP) Decreased infection rates Better able to tolerate feedings Increased IQ rates Contains long chain polyunsaturated fatty acids that help the infant’s brain develop – these are normally provided by the mother in late pregnancy, therefore preterm infants miss this Breastfeeding Mother Health Benefits Less postpartum bleeding More rapid uterine involution Weight loss More Breastfeeding Mother Health Benefits Decreased premenopausal breast cancer rates Decreased ovarian cancer rates Lactational amenorrhea Should still use progesterone only contraceptives Combined contraceptives dry up milk Breastfeeding Parent Benefits Saves money Saves time Babies love it Lactation Anatomy and Physiology Breast enlargement During pregnancy and lactation indicates the mammary glands are becoming functional Breast size before pregnancy does not determine the amount of milk a woman will produce Lactation Anatomy and Physiology Hormones during pregnancy Estrogen stimulates the ductile systems to grow, then estrogen levels drop after birth Progesterone increases the size of alveoli and lobes Inhibits milk release Prolactin contributes to increasing the breast tissue during pregnancy Lactation Anatomy and Physiology Alveoli secrete milk and contract when stimulated Oxytocin stimulates milk secretion and is released during the ‘let down’ or milk ejection reflex After let down, milk travels into the ductules, then to the larger – lactiferous or mammary ducts Lactation Anatomy and Physiology Hormones during breastfeeding Prolactin levels rise with nipple stimulation Alveolar cells make milk in response to prolactin when the baby sucks Oxytocin causes the alveoli to squeeze the newly produced milk into the duct system Lactation Anatomy and Physiology Latch On and sucking Oxytocin Release Releases Milk Infant Empties Breast Production Increases Milk Production Occurs Interference with this cycle decreases the milk supply. Breastfeeding Barriers Early breastfeeding failures deprive infants of the benefits, and leave many mothers disappointed It is a natural process, but many mothers need a lot of help Breastfeeding Barriers Must educate mothers regarding: Positioning the baby Latching on Normal nipple soreness Cramping with breastfeeding How often to feed the baby Need to wake the baby Alerting techniques Rooting Sucking Listening for swallows Preventing engorgement Nutrition Supply and demand Infant cues Breastfeeding Barriers Breast Pathology Hormonal pathology Smoking, anemia, poor nutrition, depression Psychosocial Failure of lactogenesis, hypothyroidism Overall health Flat/inverted nipples, breast reduction surgery that severed milk ducts, previous breast abscess, extremely sore nipples (cracked, bleeding, blisters, abrasions) Restrictive feeding schedules, mother without support system, not rooming in with baby, bottle supplementing when not medically required Other Previous breastfed infant who failed to gain weight well, perinatal complication (hemorrhage, htn, infection Breastfeeding Teaching methods With infant in mother’s arms Consistent information Repeat information in a variety of ways Watch the mother feed the baby and help Let the mother know she may have difficulties at first Remind mom that baby is learning with her Praise the mother’s progress, help build confidence Provide discharge support Breastfeeding The Results Baby gains weight No more than 7% weight loss Back to birth weight in 2 weeks 1oz per day weight gain for the first three months Mother is comfortable and satisfied If baby is still loosing weight on the 4th day of life: Get feeding evaluation Remember to: 1. fed the baby 2. maintain the milk supply 3. continue breastfeeding Breastfeeding Complications Infants at risk for poor weight gain Premature (less than 38 weeks) Difficulty latching on Ineffective or unsustained sucking Oral anatomic abnormalities (cleft lip/palate, short frenulum, receding chin) Multiples Jaundice Cystic fibrosis Infection Cardiac disorders Neurologic problems – downs, hypo or hypertonia Poor apgars Long labor Sleepy, nondemanding, passive temperament Separation from mother early after delivery Infants less than 5 lbs Breastfeeding Hospital Discharge Support Mother breastfeed longer if they: Are confident at hospital discharge Have a good support system after discharge Receive follow up after discharge Upon discharge Give written information Recommend mom to keep breastfeeding record Give mom phone number for a telephone helpline Lactation consultant follow-up Breastfeeding Hospital discharge support Support the mothers breastfeeding efforts Provide accurate current breastfeeding information Breastfeeding Resources for Mothers Books: Websites The Womanly Art of Breastfeeding – LeLeche League So that’s what they’re for! Breastfeeding Basic by Janet Tamaro The Breastfeeding Book by Martha and William Sears Nursing Mother Companion - Huggins Howard Common Press The Breastfeeding Answer Book – LeLeche Legue Medication and Mothers Milk – Thomas Gele PhD., a manual of lactational pharmacology 9th Ed. Breastfeeding and Human Lacation – 2nd Ed. Jan Rioden and Kathleen G. Auerbach Breastfeeding Triage Tool - Sanie Jollay and Ellen Phillips-Angeles, M.S. Ches 4th Ed. LeLecheLeague.org Medela.com Parents.com [email protected] Groups LeLeche League WIC – Public Health Department Carle’s Breast Feeding Clinic Twin clubs References Slusser Wndelin, Ms, MD and Powers Nancy G MD; Breastfeeding Update 1: Immunology, Nutrition and Advocacy; Pediatrics Review Vol 18 No. 4 Neifert, Marianne M.D., Early Assessment of Breastfeeding Infant, Contemporary Pediatrics Oct. 1996 The Breastfeeding Answer Book, LeLeche League International AWHONN – Association of Women’s Health, Obstetric and Neonatal Nurses Independent Study Module for the Clinical Management of Breastfeeding for Health Professionals 1999 Clinical Case You are seeing a 22 yo G1 P0 woman in your office for her first prenatal visit at 12 weeks gestation. When you ask her if she intends to breastfeed her baby, she replies that she is concerned that she will not be able to due to the fact she is a chronic Hepatitis B carrier. She is also concerned about the fact that her friend told her that, if she breastfeeds, she will need to do so every hour and thus will be unable to do anything else. Clinical Case Prenatal Labs Hct 33% WBC 5600/cmm (normal differential) Plt 224,000/cmm Blood type A + Antibody screen: negative Rubella titer: immune UA and Cx – negative Varicella-zoster titer: immune VDRL test: negative HBsAg: positive Clinical Case How would you counsel this patient? What infant and maternal benefits are there to breastfeeding. Clinical Case Counseling the patient: Prevalence of HBV infection in pregnancy Symptomatic – 1 to 1:1000 Asymptomatic – 5 to 15:1000 Perinatal transmission of HBV without intervention Seropositive for HBsAg only – 15-20% risk Seropositive for HBsAg and HBeAg – 85-90% risk Clinical Case Counseling the patient: Immunoprophylaxis for prevention of perinatal transmission of HBV Treat neonates immediately after birth with HBIG and HBV vaccine (must give HBIG within 12 hrs of birth) Reduces the risk of transmission to <5% First dose of HBV vaccine prior to hospital discharge, 2nd and 3rd doses administered at 1 and 6 months of age CDC recommends universal vaccination of all infants Clinical Case Counseling the patient: Breastfeeding is not contraindicated in chronic Hep-B carriers if the infant receives the HBIG and is vaccinated Clinical Case Based on your advice, the pt decides to breastfeed. She and her infant have now been successfully nursing for over 3 weeks. One morning she wakes to discover a red, wedge-shaped area in her right breast. She also has a fever to 101 degrees. What is the most likely diagnoses? How would you treat her? Clinical Case Treating the patient: Most likely diagnosis = Mastitis Give antibiotics that cover S. aureus – antistaphylococcal penicillin or first-generation cephalosporin, continue treatment for 10 days Patient should continue breastfeeding Review Question #1 1. How many calories should a lactating woman increase above her non-pregnant baseline calorie consumption? Answer #1 400 calories Review Question #2 Match the following response associated with the following conditions i. May breast feed ii. Breastfeeding not encouraged iii. Breastfeeding contraindicated A. Acute mastitis B. HSV infection C. CMV infection D. two alcoholic beverages consumed per day E. Tetracycline F. Clindamycin G. Smoking two packs of cigarettes per day H. Use of sub 50mg oral contraceptives i. HTLV 1 infection J. HBeAg + hepatitis Answer #2 A–i B–i C–i D–i E – iii F–i G–i H–i I – iii J - ii Answer #2 Breastfeeding is contraindicated in very few situations. Most viral infections are not considered contraindications. CMV has been transmitted in breast milk, but the effect on the healthy term neonate is relatively minor if breastfeeding is allowed to continue. Active acute hepatitis B (particularly if the E antigen is present), HIV, HTLV 1, cyclophosphamide, tetracycline, oral metronidizole, lithium carbonate, and radioactive agents are considered to be contraindicated during pregnancy. Puerperal mastitis is not a contraindication to breastfeeding. Review Question #3 Select the 3 correct statements comparing human mature breast milk to cow’s milk i. Calories are increased ii. Proteins are decreased iii. Fat is increased iv. Carbohydrate is increased v. Iron is increased Answer #3 i, iii, iv Human milk is significantly different from both cow’s milk and formula with iron. Human milk has 75 calories per 100ml as compared to 69 calories for cow’s milk. The protein content is approximately one third more than cow’s milk. The fat is increased by one third in human milk. Carbohydrate levels 100% increased. Although the concentration of iron I slow in human’s milk, it is more efficiently absorbed. Review Question #4 The principle function of prolactin is? A. Ensure lactation B. Sensitize the pituitary to LRH C. Increase the number of estrogen and prolactin receptors in alveolar cells Answer #4 A. LRH causes an increase in the serum prolactin level greater in pregnancy than in nonpregnancy. Prolactin insures lactation by promoting DNA synthesis in the glandular epithelial cells of the breast. It also increases the number of estrogen prolactin receptors in those cells. Prolactin promotes galactopoiesis and the production of casein and other breast products. The concentration of prolactin is approximately 10 times greater in pregnancy than it is in nonpregnancy. High concentrations of prolactin in the fetus and in amniotic fluid may have a role in preserving fetal fluid balance, preventing fetal dehydration.