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Grossly, the
cerebral
infarction at
the upper left
here
demonstrates
liquefactive
necrosis.
WHAT IS THE COMMON CAUSE OF THIS
LESION
Metaplasia of the normal esophageal squamous mucosa has
occurred here, with the appearance of gastric type columnar
mucosa
THIS IS FROM ESOPHAGUS, IDENTIFY THE
LESION
Cardiac hypertrophy
IDENTIFY THE LESION
It is a wedge-shaped pale area of coagulative necrosis
(infarction) in the renal cortex of the kidney
WHAT TYPE OF NECROSIS IS THIS?
Coagulative necrosis, adrenal infarction
Coagulative necrosis is most commonly
caused by hypoxic conditions that do not
involve severe trauma, toxins or
an acute or chronic immune response. The
lack of oxygen causes cell death in a
localised area which is perfused by blood
vessels failing to deliver primarily oxygen,
but also other important nutrients.
WHAT IS THE COMMON CAUSE OF THIS TYPE OF
NECROSIS
DRY GANGRENE
IDENTIFY THIS LESION
Giant cells are a "committee" of epithelioid macrophages. Seen
here are two Langhans type giant cells in which the nuclei are
lined up around the periphery of the cell. Additional pink
epithelioid macrophages compose most of the rest of the
granuloma
NAME THE CELL POINTED BY ARROW.
Seen here in a hilar
lymph node is a
granuloma.
Granulomas due to
infectious agents such
as mycobacteria are
often described as
"caseating" when they
have prominent
caseous necrosis
WHAT TYPE OF NECROSIS IS THIS?
Gangrenous small intestine
A
Don’t kno 
B
LABEL THIS IMAGE
A. --------------B. --------------
Normal
Pyknosis
Karyorrhexis
Label the nuclear changes seen during necrosis
Karyolysis
FAT NECROSIS
Identify the type of necrosis
Name the common cause
Caused by:
Release of activated
pancreatic lipases
into the substance of
the pancreas &
peritonial cavity