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By: Jilly B. Espinosa Nuclear Magnetic Resonance(NMR) spectroscopy NMR techniques RICHARD ROBERT ERNST 1991 NOBEL PRIZE WINNER for his contributions to the development of techniques for high-resolution nuclear magnetic resonance spectroscopy ROYAL SWEDISH ACADEMY OF SCIENCES OUTLINE: NMR Journey Love Life Early Life Educational Background Artistic Interests SWISS PHYSICAL CHEMIST He was born on AUGUST 14,1933 at Winterthur Switzerland. His father was Robert Ernst and his mother was Irma Brunner. He has two sisters. He lived in a community that combined in a unique way artistic and industrious activities. WINTERTHUR He played violoncello. He is interested in musical compositions. found a case filled with chemicals... property of his late uncle who was a metallurgical engineer ...immediately fascinated explosions! unbearable poisoning of the air in their house! read all chemistry books he could get a hand on... soon he knew he would become a chemist and not a composer I wanted to understand the secrets behind my chemical experiments and behind the processes in nature. - Ernst studied chemistry at the Swiss Federal Institute of Technology in Zurich (ETH-Z) disappointed because good memory and not impeccable logic was on demand gained descent chemical knowledge by reading... Theoretical Chemistry By S. Glasstone revealed to him the fundamentals of quantum mechanics, spectroscopy, and statistical thermodynamics pursued his PhD under the supervision of Prof. Günthard. his work dealt with the construction of high sensitivity radio frequency preamplifiers and in particular high sensitivity probe assemblies, initially for a 25 MHz, later for 75 MHz proton resonance spectrometer received both his diploma in chemistry(1957) and his Ph.D. in physical chemistry(1962) From 1963 to 1968 he worked as research chemist for Varian Associates in Palo Alto, California. discovered that the sensitivity of NMR techniques could be dramatically increased by replacing the slow sweeping radio waves traditionally used in NMR spectroscopy with short, intense pulses He returned to Switzerland to teach at his alma mater. developed a technique that enabled a highresolution, “two-dimensional” study of larger molecules than had previously been accessible to NMR 1H COSY spectrum of progesterone 3D-NMR (3D NOESY spectra, 1HC and 1HN Total NOE Correlations in a Single 3D NMR ) “I am extremely grateful for the encouragement and for the occasional readjustment of my standards of value by my wife Magdalena who stayed with me so far for more than 28 years despite all the problems of being married to a selfish work-addict with an unpredictable temper." On October 9, 1963, Ernst married Magdalena Kielholz. The couple had two daughters, Anna Magdalena and Katharina Elisabeth, and a son, Hans-Martin. All three children grew up to become educators. Ernst still counts music as one of his major interests, and he remains an enthusiastic musician. He also collects Asian art, an interest he cultivated during a trip through Asia in 1968, and is especially interested in Tibetan scroll paintings. At present, he gives lectures world-wide on magnetic resonance spectroscopy, on Fourier transform methods, on the historical development of spectroscopy, on Central Asian painting art, and on pigment analysis in paintings by Raman spectroscopy. THANK YOU ERNST!! THANK YOU FOR LISTENING!!!!!!