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Psychiatry Case Conference 1 III-B Cueto, Mary Anne – Diaz, Mark Fernan General Data L.M.P 35 y/o married Born Again Christian 2nd in a brood of 3 BS Nursing Graduate unemployed born & raised in Capiz admitted 1st time on April 4, 2005 Infomants: Patient: 75% Husband: 85% Sister: 85% Chief Complaint: insomnia, delusion of reference According to patient: “ Pinaghihiwalay ang family namin ng ministry.” According to husband: “ Hindi makatulog, minsan nagbabasa ng bible mag-isa” “ Feeling nya pinagtutulungan siya ng ministry” Personality Profile: Pre-morbid personality: “masinop, masayahin, sensitive” Morbid personality: “tahimik, kung anu anong sinasabi” History of Present Illness 2001 * very active, sings in the choir 2004 * negative feelings towards members and ministry December 2005 January 2005 February 2005 1st wk March * persistent negative feelings towards members and ministry, delusion of reference * auditory hallucination, loss of appetite, reduced sleep, negative feeling towards her husband * auditory hallucination, odd behavior, blank stares anxious History of Present Illness 2005 * quiet, unresponsive 3rd wk March 2005 * verbal aggression, delusion of reference March 25 2005 March 26 2005 March 27 2005 March 31 * felt guilty of what she said to the members, delusion of persecution * neglected her chores and children, delusion of persecution/anxiety * singing songs, speaking incomprehensible words History of Present Illness 2005 April 1 * suspicious w/her surroundings * brought to Las Pinas Doctors Hospital * injected w/unrecalled medication * admitted @ USTH while sedated Review of Systems (-) Headache, loss of consciousness, convulsions (-) fever (+) anorexia , weight loss (+) HPN – mother (+) stroke – mother (+) heart disease, PUD – father (+) alcohol dependence – father (?) nervous breakdown – great grandmother Non-smoker Non-alcoholic beverage drinker Denies use of any prohibited drugs Born to 23 y/o G2P1 (1001); NSD at home By traditional birth attendant No prenatal or postnatal complications Neuro-developmental milestones at par with age Lived with parents and three siblings Family owns a small grocery store Left in the care of the father, an alcoholic Father had occasional fights with his wife Patient admits his father had his “weaknesses” but was very affectionate and loving Patient grew-up closer to her father and siblings Primary education at Malubog-lubog Elementary School in Capiz Average student and had very few friends 6th grade - father died which caused extreme sadness and felt that a big part of her was lost with the passing Left in the care of the eldest sibling (Gina) Gina confided of being overprotective of her younger siblings Family Relationship after father’s death, mother married a policeman Siblings were against the marriage at first Patient felt that the mother betrayed her father According to the patient, she had a harmonious relationship with stepfather and stepsiblings Stepfather did not impose himself on the stepchildren was kind and approachable and was readily approachable when they need him Social Relationships Claimed to have a number of friends stayed at home on weekends because mother would not allow her to go out with friends School History Attended high school in FLAIMER Christian Institute in Capiz Wanted to take up AB Philosophy forced by mother to take up BS Nursing Graduated on time Academic Achievement failed Nursing Board Exams (1990) failure due to “poor preparation” Worked as an assistant nurse in a small clinic while waiting for the next board exams took the boards in Manila and passed with high marks (1992) Did not work at once because she was waiting for her petition from her maternal aunt to work in Germany After some time worked as a ticketing supervisor at Ever Gotesco Cinema Resigned after 2 months, thinking she was not ready to work yet Learned that her petition was declined 1993 - nurse in Capiz and resigned after 6 months Felt bad in an incident when a patient deteriorated infront of her According to sister: Patient was pious and hardworking Gave portion of salary to patients 1994- went back to Manila and stayed with sister Meaningful Long-term Relationship met Norman and married him after two years (1996) - Stayed with husband’s family (Cavite) After a few months, husband flew to Abu Dhabi Patient got pregnant and went back to Capiz Had difficult pregnancy - 1997 – CSD with her 1st child (Paul Christian) 1998 – went to Abu Dhabi with husband and had no difficulty in adjusting Worked as sales clerk in a pharmacy December 1999 – decided to return to Philippines due to 2nd pregnancy 2000 – gave birth to second child (Patricia Lois) Stayed with her mother, who sometimes helped out with her grandchildren Longed for her husband 2001 – returned to UAE with her children because of argument with mother Was baptized to a ALL Nations FULL GOSPEL, a Born Again Christian group Planned to work as a nurse however got pregnant with her 3rd child First worked as an assistant nurse Very little compensation while waiting for the next board exams resigned to take 2nd board exam Worked as Ticketing supervisor and resigned after 2 mos Petition by her maternal aunt was declined by the German Embassy 1998 - sales clerk in a pharmacy in Abu Dhabi 1999 - resigned because of 2nd pregnancy No difficulty adapting to new environment No difficulty adjusting to new role as mother Cesar Minerva 58 199 6 Gina L 35 4 Norman LEGEN D Heart attack Stroke Paul Patricia Christian Lois 12 9 8 PUD HPN Cesar- father Died of “heart attack” at 45 An elementary graduate Came from a well off family in Capiz Alcoholic since 20 y/o Drank gin (? amount) almost everyday usually alone or with friends Patient regards him as loving and kind father Patient claims she got her talent from him He usually sang with her SALIENT FEATURES 35 y/o Female Born again Christian Unemployed Preoccupation with at least 2 delusions (JanMarch2005) Auditory hallucination Aggressive/agitated behavior (March 2005) Avolition-apathy (3rd wk & 27 Mar) SALIENT FEATURES Incomprehensible speech Impaired social functioning Physiologic disturbance: anorexia and insomnia Family history: great grandmother had nervous breakdown Non-smoker, non-alcoholic, denies use of prohibited drugs Poor relation with mother DIFFERENTIAL DIAGNOSIS Major Depressive Disorder Bipolar Disorder Schizophrenia DSM-IV-TR Diagnostic Criteria for Major Depressive Episode A. FIVE (OR MORE) OF THE FOLLOWING SYMPTOMS HAVE BEEN PRESENT DURING THE SAME 2-WEEK PERIOD AND REPRESENT A CHANGE FROM PREVIOUS FUNCTIONING; AT LEAST ONE OF THE SYMPTOMS IS EITHER (1) DEPRESSED MOOD OR (2) LOSS OF INTEREST OR PLEASURE. NOTE: DO NOT INCLUDE SYMPTOMS THAT ARE CLEARLY DUE TO A GENERAL MEDICAL CONDITION, OR MOOD-INCONGRUENT DELUSIONS OR HALLUCINATIONS. 1. depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g. appears tearful). Note: In children and adolescents, can be irritable mood. 2. markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others) 3. significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day. Note: In children, consider failure to make expected weight gains. 4. insomnia or hypersomnia nearly every day 5. psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down) 6. fatigue or loss of energy nearly every day 7. feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick) 8. diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective account or as observed by others) 9. recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide B. THE SYMPTOMS DO NOT MEET CRITERIA FOR A MIXED EPISODE. C. THE SYMPTOMS CAUSE CLINICALLY SIGNIFICANT DISTRESS OR IMPAIRMENT IN SOCIAL, OCCUPATIONAL, OR OTHER IMPORTANT AREAS OF FUNCTIONING. D. THE SYMPTOMS ARE NOT DUE TO THE DIRECT PHYSIOLOGICAL EFFECTS OF A SUBSTANCE (E.G., A DRUG OF ABUSE, A MEDICATION) OR A GENERAL MEDICAL CONDITION (E.G., HYPOTHYROIDISM). E. THE SYMPTOMS ARE NOT BETTER ACCOUNTED FOR BY BEREAVEMENT, I.E., AFTER THE LOSS OF A LOVED ONE, THE SYMPTOMS PERSIST FOR LONGER THAN 2 MONTHS OR ARE CHARACTERIZED BY MARKED FUNCTIONAL IMPAIRMENT, MORBID PREOCCUPATION WITH WORTHLESSNESS, SUICIDAL IDEATION, PSYCHOTIC SYMPTOMS, OR PSYCHOMOTOR RETARDATION. DSM-IV-TR Diagnostic Criteria for Manic Episode A. A distinct period of abnormally and persistently elevated, expansive, or irritable mood, lasting at least 1 week (or any duration if hospitalization is necessary). B. During the period of mood disturbance, three (or more) of the following symptoms have persisted (four if the mood is only irritable) and have been present to a significant degree: inflated self-esteem or grandiosity 2. decreased need for sleep (e.g., feels rested after only 3 hours of sleep) 3. more talkative than usual or pressure to keep talking 4. flight of ideas or subjective experience that thoughts are racing 5. distractibility (i.e., attention too easily drawn to unimportant or irrelevant external stimuli) 6. increase in goal-directed activity (either socially, at work or school, or sexually) or psychomotor agitation 7. excessive involvement in pleasurable activities that have a high potential for painful consequences (e.g., engaging in unrestrained buying sprees, sexual indiscretions, or foolish business investments) C. The symptoms do not meet criteria for a Mixed Episode. D. The mood disturbance is sufficiently severe to cause marked impairment in occupational functioning or in usual social activities or relationships with others, or to necessitate hospitalization to prevent harm to self or others, or there are psychotic features. E. The symptoms are not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication, or other treatments) or a general medical condition (e.g., hyperthyroidism). DSM-IV-TR Diagnostic Criteria for Hypomanic Episode A. A distinct period of persistently elevated, expansive, or irritable mood, lasting throughout at least 4 days, that is clearly different from the usual nondepressed mood. B. During the period of mood disturbance, three (or more) of the following symptoms have persisted (four if the mood is only irritable) and have been present to a significant degree: 1. inflated self-esteem or grandiosity 2. decreased need for sleep (e.g., feels rested after only 3 hours of sleep) 3. more talkative than usual or pressure to keep talking 4. flight of ideas or subjective experience that thoughts are racing 5. distractibility (i.e., attention too easily drawn to unimportant or irrelevant external stimuli) 6. increase in goal-directed activity (either socially, at work or school, or sexually) or psychomotor agitation 7. excessive involvement in pleasurable activities that have a high potential for painful consequences (e.g., engaging in unrestrained buying sprees, sexual indiscretions, or foolish business investments) C. The episode is associated with an unequivocal change in functioning that is uncharacteristic of the person when not symptomatic. D. The disturbance in mood and the change in functioning are observable by others. E. The episode is not severe enough to cause marked impairment in social or occupational functioning, or to necessitate hospitalization, and there are no psychotic features. F. The symptoms are not due to the direct physiological effects of a substance (e.g., a drug of abuse, a medication, or other treatment) or a general medical condition (e.g., hyperthyroidism). DSM-IV-TR Diagnostic Criteria for Schizophrenia A. CHARACTERISTIC SYMPTOMS: TWO OR MORE OF THE FOLLOWING, EACH PRESENT FOR A SIGNIFICANT PORTION OF TIME DURING A ONE-MONTH PERIOD (OR LESS IF SUCCESFULLY TREATED) 1. Delusions 2. Hallucinations 3. Disorganized Speech 4. Grossly Disorganized or Catatonic Behavior 5. Negative Symptoms B. SOCIAL/OCCUPATIONAL DYSFUNCTION C. DURATION: continous signs for atleast 6 months that must include: 1 month of active symptoms (or < if succesfully treated) ± periods of prodromal or residual symptoms •only negative symptoms •2 or more Criteria A symptoms in attenuated form (eg. Odd beliefs, unusual perceptual experience D.SCHIZOAFFECTIVE DISORDER EXCLUSION E. SUBSTANCE/ GENERAL MEDICAL CONDITION EXCLUSION F. RELATIONSHIP TO A PERVASIVE DISORDER DSM-IV-TR Diagnostic Criteria for Schizophrenia Subtypes PARANOID TYPE A.PREOCCUPATION WITH ONE OR MORE DELUSIONS OR FRQUENT HALLUCINATIONS B. NO DISORGANIZED SPEECH, DISORGANIZED OR CATATONIC BEHAVIOR, FLAT OR INAPPROPRIATE AFFECT DISORGANIZED TYPE A. ALL OF THE FOLLOWING ARE PROMINENT: 1. Disorganized Speech 2. Disorganized Behavior 3. Flat or Inappropriate Affect B. THE CRITERIA ARE NOT MET FOR CATATONIC TYPE CATATONIC TYPE A type of schizophrenia in which the clinical picture is dominated by at least two of the following: 1. Motoric immobility as evidenced by catalepsy or stupor 2. Excessive motor activity 3. Extreme negativism 4. Peculiarities of voluntary movement as evidenced by posturing, stereotypied movements, prominent mannerisms, prominent grimacing 5. Echolalia or echopraxia UNDIFFERENTIATED TYPE A type of schizophrenia in which symptoms meet Criterion A present, but the criteria are not met for the paranoid, disorganized, or catatonic type RESIDUAL TYPE A.Absence of prominent delusions, hallucinations, disorganized speech, and grossly disorganized speech and grossly disorganized, or catatonic behavior B. There is continuing evidence of the disturbance, as indicated by the presence of negative symptoms listed in Criterion A for schizophrenia present in attenuated from