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THE OVARIES And the Corresponding Hormones and Gland By: Caitlin Beamer, Katie Waito, and Heather Campbell LOCATION OF GLAND www.pennstatehershey.org Behind the Bladder Near the Colon On sides of the uterus On the Fallopian Tubes Has anchors HORMONES PRODUCED 2 Steroid Hormones 1. Estrogen • Produced in the ovaries, liver, adrenal glands, and breasts 2. Progesterone • • Produced in the brain, ovaries, and in pregnant woman’s uteruses Found in milk TARGET CELLS Target Cells- are cells that alter their genetic material in reaction to a hormone that binds to the cell’s protein receptors. Estrogen: Uterine cells, Lipid cells, Breast cancer cells Progesterone: Myometrium cells, PR-A, and PR-B cells EFFECTS OF THE HORMONES Estrogen Dominance – is when there is an imbalance of progesterone and estrogen, either high levels of estrogen or low levels of progesterone. Progesterone counter balances estrogen. Some effects of Estrogen Dominance Headaches and anxiety Poor sleep patterns Impairs blood sugar control, at risk of blood clots Reduces oxygen levels in cells Increases risk of breast and prostate cancer EFFECT OF THE HORMONES CONT’D Some effects of Normal levels of Estrogen Enlarges breasts and hips Decreases growth rate Increases metabolic rate Thickens the uterine lining Stimulates the endometrium Lubricates the vagina Skin and bone health Some effects of Lower levels of Estrogen Relieves hot flashes Improves memory Improves sleeping disorders EFFECT OF THE HORMONES CONT’D Some effects of Excess Progesterone Levels Over Tired Depression Digestive Problems Some effects of Normal Progesterone Levels Improves voice tone Stimulates new bone production Restores proper oxygen levels in cells Decreases risk for cancer Some effects of Lower Progesterone Levels Increase of heart, gall bladder, and autoimmune diseases Increases risk of certain cancers TRIGGERS/ CONTROLS Estrogen is stimulated by the follicle-stimulating hormone (FSH) FSH is controlled by another hormone called gonadotrophin releasing hormone (GnRH) Progesterone is stimulated by the luteinizing hormone (LH) LH is also stimulated by GnRH Hypothalamus ---> GnRH --->Pituitary --->FSH---> Folicle ---> Estrogen Hypothalamus ---> GnRH ---> Pituitary ---> LH---> Corpus luteum ---> Progesterone TRIGGERS/ CONTROLS CONT’D http://users.rcn.com/jkimball.ma.ultran et/BiologyPages/S/SexHormones.html# Regulation COMPLICATIONS Extreme Lack of Estrogen •Lack of periods •Hot flashes •Thinning, wrinkling and general aging of skin •Libido, vaginal dryness •Mood swings •Osteoporosis •More likely for heart disease COMPLICATIONS CONT’D Extreme Lack of Progesterone • • • Anxiety/ depression Malfunctioning thyroid gland Increased risk of uterine cancer WORKS CITED Definition: Ovaries. (n.d.). Retrieved June 8, 2009, from http://www.sharedjourney.com/define/ova.html Ellis-Christensen, T. (2009, June 7). What are Some Low Progesterone Symptoms?. Retrieved June 8, 2009, from http://www.wisegeek.com/what-are-some-low-progesterone-symptoms.htm Estrogen Target Cells. (n.d.). Retrieved June 8, 2009, from http://sciencedirect.com Estrogen or Progesterone. (n.d.). Retrieved June 5, 2009, from http://biomedx.com/bones/page10.html Hormones of the Reproductive System. (2007, June 23). Retrieved June 7, 2009, from http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/SexHormones.html#Regulation Hormones. (n.d.). Retrieved June 8, 2009, from http://www.daisynetwork.org.uk/hormones.html Howlett, D. T. (n.d.). Hormone Replacement Therapy . Retrieved June 7, 2009, from www.lnrmed.org.uk/Endocrinology/Endo_PDF/HRT%20Information%20Sheet.pdf Lee, J. R., Zava, D., & Hopkins., V. (n.d.). Effects of Progesterone & Estrogen. Retrieved June 8, 2009, from http://www.johnleemd.com/store/premenstrual_syndrome.html Ovaries And Testes.. (n.d.). Retrieved June 8, 2009, from http://www.herbs2000.com/h_menu/gl_ovaries_testes.htm Parker, M. (n.d.). Complications of Ovarian Cysts Can Be Dangerous. Retrieved June 8, 2009, from http://www.buzzle.com/articles/complications-of-ovarian-cysts-can-be-dangerous.html Pieber, D., Allport, V., Hills, F., Johnson, M., & Bennett, P. (n.d.). Interactions between progesterone receptor isoform...[Mol Hum Reprod. 2001] - PubMed Result . Retrieved June 8, 2009, from http://www.ncbi.nlm.nih.gov/pubmed Progesterone. (2002, February 20). Retrieved June 8, 2009, from http://www.healthywomen.org/healthtopics/progesterone system, Â. s., & Â glands, t. (n.d.). endo.gl. Retrieved June 5, 2009, from http://library.thinkquest.org/26164/END.GLA.html