Download CURRICULUM VITAE

CURRICULUM VITAE
Stefan W. Stoll, Ph.D.
Research Assistant Professor
Department of Dermatology
University of Michigan
7415 Medical Science Building I
1301 E. Catherine St.
Ann Arbor, MI 48109-5675
Phone: 734-763-5033
Fax: 734-615-7277
[email protected]
EDUCATION AND TRAINING
1989
1993
1993-1996
1997-1998
Eberhard Karls University, Tübingen, Germany
Biology, Diplom (M.S.)
Mentor: Prof. Dr. Hans J. Lipps
Eberhard Karls University, Tübingen, Germany
Genetics, Dr. rer. nat. (Ph.D.)
Mentor: Prof. Dr. Hans J. Lipps
Postdoctoral Research Fellow, Department of Dermatology,
University of Michigan, Ann Arbor, Michigan
Mentor: Dr. James T. Elder
Research Associate, Department of Dermatology, University of
Michigan, Ann Arbor, Michigan
ACADEMIC APPOINTMENTS
1998–2007
2007-
Research Investigator, Department of Dermatology,
University of Michigan, Ann Arbor, Michigan
Research Assistant Professor, Department of Dermatology,
University of Michigan, Ann Arbor, Michigan
RESEARCH INTERESTS
Epidermal growth factor receptor (EGFR) signaling in skin
Keratinocyte migration, proliferation, differentiation and survival
Metalloproteinase regulation of ErbB signaling
Epithelial-mesenchymal transition
Psoriasis
Wound Repair
C.V. Stefan W. Stoll
December 2014
1
RESEARCH SUPPORT
Active
National Institutes of Health
“Functional Genomics of Psoriasis”
1R01-AR065183-01
Co-Investigator
09/15/13 - 07/31/17
Pending
National Institutes of Health
“Novel Functions of HB-EGF in Breast Cancer”
1R21-CA195289-01
Principal Investigator
04/01/15 - 03/31/17
Veterans Administration Merit Review
“Novel Functions of EGF Receptor Ligands in Head and
Neck Cancer”
Co-Investigator
10/01/14 - 09/30/18
Recent
National Psoriasis Foundation
Discovery Research Grant Award
“Functional analysis of the psoriasis susceptibility gene
TRAF3IP2 in human keratinocytes”
Principal Investigator
07/01/11–06/30/12
National Institutes of Health
“Metalloproteinase regulation of ErbB signaling in skin”
1K01-AR050462
Principal Investigator
07/15/06 – 06/30/11
National Institutes of Health
“Metalloproteinase regulation of ErbB signaling in skin”
5R03-AR049420
Principal Investigator
04/01/04 – 03/31/07
Dermatology Foundation Research Career Development Award
C.V. Stefan W. Stoll
December 2014
2
“ErbB / Integrin Regulation of Re-epithelialization”
Principal Investigator
07/01/98–02/28/02
University of Michigan Medical School Clinical Research
Partnership Fund
“JNK/TGF-Beta Signaling in Cutaneous Wound Healing”
Co-Investigator
02/01/99 – 01/31/01
Dermatology Foundation Research Grant
“ErbB / Integrin Regulation of Re-epithelialization”
Principal Investigator
07/01/99 – 06/30/00
Dermatology Foundation Research Fellowship
“EGF Receptor Regulation of Apoptosis in Wound Healing”
07/01/97 - 06/30/98
Dermatology Foundation Research Grant
“Role of Keratinocyte EGF Receptor Activation in Human Skin
Angiogenesis”
07/01/95– 06/30/96
HONORS AND AWARDS
1991
1993
1995
1997
1998 -2001
1999
Ph.D. Student Travel Award (IV. Int. Congress in Ciliate
Molecular Biology, Asilomar, California), Teufel Foundation,
Germany
Magna cum Laude, University of Tübingen, Germany
American Society for Dermatologic Surgery Research Grant
Award
Paul Janssen Dermatology Foundation Research Fellowship
Award
Arden/Lever/Chesebrough-Pond’s Dermatology Foundation
Research Career Development Award
Dermatology Foundation Research Grant Award
SEMINARS AND INVITED PRESENTATIONS
C.V. Stefan W. Stoll
December 2014
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1992
1994
1995
1996
1996
1997
1998
1998
1999
2000
2002
2003
2006
C.V. Stefan W. Stoll
Annual Meeting of the German Society of Genetics, Tübingen,
Germany, “The organization of internal telomeric repeats in the
polytene chromosomes of Stylonychia lemnae”.
Annual Meeting of the Society of Investigative Dermatology,
Baltimore, MD, “Selective overexpression of heparin-binding
EGF-like growth factors in malignant and regenerative
epidermal hyperplasia”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “EGF receptor regulation
of EGF-like growth factor mRNA stability in keratinocytes”.
Annual Meeting of the Society of Investigative Dermatology,
Washington DC, “Autoinductive EGF receptor activation is an
important early event in cutaneous wound healing”.
Monthly Research Conference of the Cancer Research Division
of Parke Davis Pharmaceutical Research/Warner Lambert, Ann
Arbor, MI, “Autoinductive EGF receptor activation is an
important early event in cutaneous wound healing”.
Annual Meeting of the Society of Investigative Dermatology,
Washington DC, “Epidermal growth factor receptor activation
mediates keratinocyte survival via bcl-XL”.
Scientific Symposium at Unilever Research US Laboratory,
Edgewater, NJ, “ErbB receptor expression and function in
cutaneous wound healing”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “EGF receptor activation
and function in wound healing”.
Annual Meeting of the Society of Investigative Dermatology,
Chicago, IL, “Early gene responses in organ culture are MAP
kinase-dependent, whereas keratinocyte outgrowth is p38dependent”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Multiple ErbB receptors
are expressed and functional in keratinocytes and skin”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Metalloproteinases
stimulate ErbB-dependent ERK signaling in human skin organ
culture”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Metalloproteinasemediated, context-dependent activation of EGF-like growth
factors in keratinocytes”.
Annual Meeting of the Society of Investigative Dermatology,
Philadelphia, PA, “Differential expression and function of EGF
December 2014
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2006
2007
2008
2009
2009
2010
2010
2012
2013
2014
2014
receptor ligands influence autocrine keratinocyte proliferation
and morphology”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “EGFR ligand
expression and function in human keratinocytes and skin”.
Annual Meeting of the Society of Investigative Dermatology,
Los Angeles, “Inducible expression of amphiregulin-specific
small hairpin RNA blocks autocrine growth of human
keratinocytes”.
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Inhibition of human
keratinocyte growth by amphiregulin-specific shRNA”
Department of Urology Research Conference, University of
Michigan “Differential expression and function of EGFR ligands
influence keratinocyte proliferation and migration”.
Department of Surgery, University of Michigan“ “Differential
EGFR ligand expression and function influence keratinocyte
proliferation and migration”.
Annual Meeting of the Society of Investigative Dermatology,
Atlanta, GA, “Amphiregulin carboxyterminal domain is required
for autocrine keratinocyte growth.”
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Novel Functions of
Amphiregulin in Keratinocyte Growth and Differentiation”
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Amphiregulin
Cytoplasmic Domain Controls Cell Cycle Regulatory Gene
Expression in Human Keratinocytes”
Cell Division Club, University of Michigan, Ann Arbor, MI,
“Amphiregulin Cytoplasmic Domain Controls Cell Cycle
Regulatory Gene Expression in Human Keratinocytes”
Annual Meeting of the Society of Investigative Dermatology,
Albuquerque, NM, “Amphiregulin supports G2/M progression
via FoxM1 and inhibits differentiation in human
keratinocytes“
Research Conference of the Department of Dermatology,
University of Michigan, Ann Arbor, MI, “Novel Functions of
Amphiregulin and HB-EGF in Epithelial Cell Growth and
Survival"
MEMBERSHIPS IN PROFESSIONAL SOCIETIES AND
ORGANIZATIONS
1996
1998
2009
C.V. Stefan W. Stoll
Center for Organogenesis, University of Michigan
Society of Investigative Dermatology, Cleveland, OH
Comprehensive Cancer Center, University of Michigan
December 2014
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SCIENTIFIC ACTIVITIES
Ad Hoc Reviewer
1998 –
to present
American Journal of Pathology, American Journal of
Physiology, Archives of Dermatological Research, British
Journal of Dermatology, Cell Biology and Toxicology,
Biochemical Journal, Drug Discovery Today, Experimental
Dermatology, International Journal of Nanomedicine, Journal of
Dermatological Science, Journal of Investigative Dermatology,
Plos One, Nature Biotechnology, Oncogene, Trends Journals,
Wound Repair and Regeneration
BIBLIOGRAPHY
Completed Publications in Scientific Journals
Peer-Reviewed Publications
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Stoll S, Schmid M, and Lipps HJ: The organization of macronuclear
sequences associated with C4A4-repeats in the polytene chromosome
stage of Stylonychia lemnae. Chromosoma 100:300-304, 1991.
Stoll S, Zirlik T, Maercker C, and Lipps HJ: The organization of
internal telomeric sequences in the polytene chromosomes of
Stylonychia lemnae. Nucleic Acids Research 21:1783-1788, 1993.
Hardas BD, Zhao XP, Zhang J, Xia L-Q, Stoll S, Elder J T:
Assignment of psoriasin to human chromosomal band 1q21. Journal of
Investigative Dermatology 106:753-758, 1996.
Andersen LB, Xia L-Q, Stoll S, Zhao XP, Elder JT: Lineage-specific
CaN19 expression in human skin: lack of expression in normal
melanocytes. Journal of Dermatological Science 12:69-72, 1996.
Xia L-Q, Stoll SW, Liebert M, Ethier SP, Carey T, Esclamado R,
Carroll W, Johnson T, Elder JT: CaN19 expression in benign and
malignant hyperplasia of the skin and oral mucosa: Evidence for a role
in regenerative differentiation.
Cancer Research 57: 3055-3062,
1997.
Maercker C, Stoll S, Rosenkranz K, Becker E-M, Lipps HJ: A family of
repetitive sequences eliminated late during macronuclear development
of the hypotrichous ciliate Stylonychia Lemnae.
Developmental
Genetics 21 (3): 201-211, 1997.
Stoll S, Garner W, Elder J: Heparin-binding ligands mediate autocrine
EGF receptor activation in skin organ culture. Journal of Clinical
Investigation 100 (5): 1271-1281, 1997.
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Stoll SW, Zhao XP, Elder JT: EGF receptor activation stimulates
transcription of CaN19 (S100A2) in human keratinocytes. Journal of
Investigative Dermatology 111: 1092-1097, 1998.
Stoll SW, Benedict M, Mitra R, Hiniker A, Elder JT, Nuñez G: EGF
receptor signaling promotes keratinocyte survival by inhibiting
apoptosis through bcl-XL. Oncogene 16: 1493-1499 1998.
Stoll SW and Elder JT: Retinoid regulation of heparin-binding EGFlike growth factor expression in human keratinocytes and skin.
Experimental Dermatology 7: 391-397, 1998.
Varani J, Kang S, Stoll S, Elder JT: Human psoriatic skin in organ
culture: Comparison with normal skin exposed to exogenous growth
factors and effects of an antibody to the EGF receptor. Pathobiology
66: 252-259, 1998.
Stoll SW and Elder JT: Differential regulation of EGF-like growth
factor genes in human keratinocytes. Biochemical and Biophysical
Research Communications 265: 214-221, 1999.
Deshpande R, Woods TL, Fu J, Zhang T, Stoll SW, Elder JT:
Biochemical characterization of S100A2 in human keratinocytes:
subcellular localization, dimerization, and oxidative cross-linking.
Journal of Investigative Dermatology 115:477-85, 2000.
Stoll SW, Chia NVC, Nair RP, Woods TL, Stuart P, Henseler T,
Jenisch S, Christophers E, Voorhees JJ, Elder JT: S100A2 coding
sequence polymorphism: Characterization and lack of association with
psoriasis. Clinical and Experimental Dermatology 26: 79-83, 2001.
Stoll SW, Kansra S, Peshick P, Fry D, Leopold W, Wiesen JF, Sibilia
M, Werb Z, Derynck R, Wagner E, Elder JT: Differential utilization and
localization of ErbB Receptor tyrosine kinases in skin compared to
normal and malignant keratinocytes. Neoplasia 3: 339-350, 2001.
Varani J, Zeigler M, Dame MK, Kang S, Fisher GJ, Voorhees JJ, Stoll
SW, Elder JT: Heparin-binding epidermal-growth-factor-like growth
factor activation of keratinocyte ErbB receptors mediates epidermal
hyperplasia, a prominent side-effect of retinoid therapy. Journal of
Investigative Dermatology 117: 1335-1341, 2001.
Stoll SW, Kansra S, Elder JT: Metalloproteinases stimulate ErbBdependent ERK signaling in human skin organ culture. Journal of
Biological Chemistry 277: 26839-45, 2002.
Kansra S, Stoll SW, Elder JT: Differential cytoskeletal association of
ErbB1 and ErbB2 during keratinocyte differentiation. Biochemical and
Biophysical Research Communications, 295: 1108-17, 2002.
Stoll SW, Kansra S, Elder JT: Keratinocyte outgrowth from human
skin explant cultures is dependent upon p38 signaling. Wound Repair
and Regeneration, 11: 346-53, 2003.
C.V. Stefan W. Stoll
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* Kansra S, * Stoll SW, Johnson JL, Elder JT: Autocrine ERK
activation in normal human keratinocytes: metalloproteinase-mediated
release of amphiregulin triggers signaling from ErbB1 to ERK.
Molecular Biology of the Cell, 15: 4299-4309, 2004.
* indicates equal contributions
Elder, JT, Kansra S, Stoll SW. Autocrine regulation of keratinocyte
proliferation. J Clin Ligand Assay, 27: 137-142, 2004.
Kansra S, Stoll SW, Johnson JL, Elder JT: Src family kinase inhibitors
block amphiregulin-mediated autocrine ErbB signaling in normal
human keratinocytes. Molecular Pharmacology, 67: 1145-57, 2005.
Rittié L, Kansra S, Stoll SW, Li Y, Gudjonsson JE, Shao Y, Michael
LE, Fisher GJ, Johnson TM, Elder JT: Differential ErbB1 signaling in
squamous cell versus basal cell carcinoma of the skin. American
Journal of Pathology, 170: 2089-99, 2007.
Li Y, Gudjonsson JE, Woods TL, Zhang T, Johnston A, Stoll SW,
Elder JT: Transgenic expression of S100A2 in hairless mouse skin
enhances CXCL13 mRNA in response to solar-simulated radiation.
Arch Dermatol Research, 301: 205-217, 2009.
Rittié L, Stoll SW, Kang S, Voorhees JJ, Fisher GJ: Hedgehog
Signaling Maintains Hair Follicle Stem Cell Phenotype in Young and
Aged Human Skin. Aging Cell, 8(6): 738-51, 2009.
Stoll SW, Johnson JL, Bhasin A, Johnston A, Gudjonsson JE, Rittie L,
Elder JT: Metalloproteinase-mediated, context-dependent function of
amphiregulin and HB-EGF in human keratinocytes and skin. Journal of
Investigative Dermatology, 130(1): 295-304, 2010.
Gudjonsson JE, Johnston A, Stoll SW, Riblett M, Xing X, Kochkodan
JJ, Ding J, Nair RP, Aphale A, Voorhees JJ, Elder JT: Evidence for
altered Wnt signaling in psoriatic skin. Journal of Investigative
Dermatology, 130(7): 1849-59 2010.
Stoll SW, Johnson JL, Li Y, Rittié L, Elder JT: Amphiregulin carboxyterminal domain is required for autocrine keratinocyte growth. Journal
of Investigative Dermatology, 130(8): 2031-40, 2010.
Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, Raelson JV,
Belouchi M, Fournier H, Reinhard C, Ding J, Li Y, Tejasvi T,
Gudjonsson J, Stoll SW, Voorhees JJ, Lambert S, Weidinger S,
Eberlein B, Kunz M, Rahman P, Gladman D, Gieger C, Wichmann HE,
Karlsen TH, Kabelitz D, Mrowietz U, Abecasis GR, Elder JT, Schreiber
S, Weichenthal M, Franke A. Genome-wide association study reveals
association of psoriasis with TRAF3IP2. Nature Genetics 42:991-995,
2010.
Johnston A, Gudjonsson JE, Aphale A, Guzman AM, Stoll SW, Elder
JT: EGFR and IL-1 synergistically promote keratinocyte antimicrobial
defenses in a differentiation-dependent fashion. Journal of
Investigative Dermatology 131: 329-37, 2011.
C.V. Stefan W. Stoll
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Stoll SW, Rittié L, Johnson JL, Elder JT: Heparin-binding EGF-like
growth factor promotes epithelial to mesenchymal transition in human
keratinocytes. Journal of Investigative Dermatology 32(9): 2148-57,
2012.
Foster AM, Baliwag J, Chen CS, Guzman AM, Stoll SW, Gudjonsson
JE, Ward NL, Johnston A: IL-36 promotes myeloid cell infiltration,
activation and inflammatory activity in skin. Journal of Immunology
192 (12): 6053-6061, 2014
Abstracts
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Stoll S, Eder C, and Lipps HJ: Macronuclear DNA sequence
organization in the polytene chromosomes of Stylonychia lemnae. IV.
Int. Congress in Ciliate Molecular Biology, Asilomar, California, 95:
1991.
Stoll S, Zirlik T, Lipps HJ: The organization of internal telomeric
repeats in the polytene chromosomes of Stylonychia lemnae. Annual
Meeting of the German Society of Genetics, Tübingen, Germany 1992.
Xia L-Q, Stoll SW, Hardas BD, Liebert M, Grossman HB, Carroll W,
Esclamado R, Beer DG, Nelson BR, Johnson TM, Elder JT: Loss of
CaN19 expression is a common event during epithelial tumor
progression in vivo.
Journal of Investigative Dermatology, 102
(4):652A, 1994.
Stoll SW, Xia L-Q, Elder JT: Selective overexpression of heparinbinding EGF-like growth factors in malignant and regenerative
epidermal hyperplasia. Journal of Investigative Dermatology, 102
(4):531A, 1994.
Stoll SW, Elder JT: EGF receptor activation regulates expression of
multiple keratinocyte-derived EGF-like growth factor mRNAs by
increasing transcript stability. Journal of Investigative Dermatology,
104 (4):675A, 1995.
Stoll SW, Elder JT: Heparin-binding EGF-like growth factors induce
vascular permeability factor via autocrine EGF receptor activation:
Early events in wound healing. Journal of Investigative Dermatology,
104 (4):678A, 1995.
Xia L-Q, Stoll SW, Nelson B, Elder JT: CaN19 expression is
perilesional in BCC and pan-epidermal in psoriasis: A marker for
regenerative hyperplasia? Journal of Investigative Dermatology, 104
(4):635A, 1995.
Stoll SW, Xia LQ, Zhao XP, Elder JT: CaN19 and keratin 6 gene
expression during regenerative hyperplasia: Antagonistic roles of EGF
receptor activation and calcium. Journal of Investigative Dermatology,
106:863A, 1996.
C.V. Stefan W. Stoll
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Zhao XP, Stoll SW, Elder JT: CaN19 is transcriptionally activated by
EGF in human KC. Journal of Investigative Dermatology, 106:817A,
1996.
Stoll SW, Elder JT: Autoinductive EGF receptor activation is an
important early event in cutaneous wound healing.
Journal of
Investigative Dermatology, 106:820A, 1996.
Stoll SW, Xia L-Q, Elder JT: Antagonistic effects of retinoic acid and
calcium on heparin-binding EGF-like growth factor expression in
human skin organ culture. Journal of Investigative Dermatology,
106:910A, 1996.
Stoll SW, Benedict M, Mitra R, Hiniker A, Nuñez G, Elder JT:
Epidermal growth factor receptor activation mediates keratinocyte
survival via bcl-XL. Journal of Investigative Dermatology, 108: 568A,
1997.
Stoll SW, Sciabica M, Wiesen J, Werb Z, Elder JT: Induction of HBEGF mRNA is intact in skin organ cultures of EGFR knockout mice.
Journal of Investigative Dermatology, 110: 625A, 1998.
Stoll SW and Elder JT: Early gene responses in organ culture are
MAP kinase-dependent, whereas keratinocyte outgrowth is p38dependent. Journal of Investigative Dermatology, 112: 554A, 1999.
Stoll SW and Elder JT: Normal human keratinocyte require ErbB
tyrosine kinases other than ErbB1/EGFR for growth. Journal of
Investigative Dermatology, 112: 642A, 1999.
Woods TL, Stoll SW, Elder JT: Identification of an S100A2 binding
protein in human keratinocytes. Journal of Investigative Dermatology,
112: 625A, 1999.
Woods TL, Fu J, Desphande R, Zhang T, Stoll SW, Elder JT:
Intermolecular disulfide crosslinking of S100A2 is induced by oxidative
stress in normal human keratinocytes.
Journal of Investigative
Dermatology, 114: 847A, 2000.
Chia NVC, Stoll SW, Woods TL, Nair RP, Stuart P, Elder JT: S100A2
coding sequence polymorphism is not associated with psoriasis.
Journal of Investigative Dermatology, 114: 866A, 2000.
Kansra S, Stoll SW, Elder JT:
EGF-dependent cytoskeletal
association of activated MAP kinase and other tyrosine
phosphoproteins in human keratinocytes. Journal of Investigative
Dermatology, 114: 735A, 2000.
Stoll SW, Kansra S, Elder JT: Expression of multiple members of the
ErbB receptor family in human skin organ culture. Journal of
Investigative Dermatology, 114: 744A, 2000.
Varani J, Zeigler M, Kang S, Fisher G, Voorhees J, Stoll SW, Elder J:
HB-EGF activation of keratinocyte ErbB receptors mediates epidermal
hyperplasia, a common side-effect of retinoid therapy. Journal of
Investigative Dermatology, 117:403A, 2001.
C.V. Stefan W. Stoll
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Stoll SW, Kansra S, Elder J: Metalloproteinases stimulate ErbBdependent ERK signaling in human skin organ culture. Journal of
Investigative Dermatology, 117: 279A, 2002.
Stoll SW, Kansra S, Elder JT: Lysophosphatidic acid-induced EGF
receptor internalization in human keratinocytes depends on
metalloproteinase activity. Journal of Investigative Dermatology, 121:
768A, 2003.
Kansra S, Stoll SW, Johnson JL, Elder JT: Blockade of ERKdependent autocrine keratinocyte proliferation by Src family kinase
inhibitors and calcium. Journal of Investigative Dermatology, 122: A99,
2004
Stoll SW, Elder JT: Metalloproteinase-mediated, context-dependent
activation of EGF-like growth factors in human keratinocytes. Journal
of Investigative Dermatology, 122: A101, 2004.
Stoll SW, Johnson JL, Elder JT: LPA stimulates amphiregulin
shedding in human kerationcytes: lack of evidence for ADAM10
involvement. J Invest Dermatol 124: A97, 2005 A97, 2005
Stoll SW, Johnson JL, Rittie L, Elder JT: Differntial expression and
function of EGF receptor ligands influence autocrine keratinocyte
proliferation and morphology. Journal of Investigative Dermatology,
126: A565, 2006.
Stoll SW, Johnson JL, Elder JT: Inducible expression of amphiregulinspecific small hairpin RNA blocks autocrine growth of human
keratinocytes. Journal of Investigative Dermatology, 127: A608, 2007.
Gudjonsson J, Tejasvi T, Aphale A, Stoll SW, Nair R, Voorhees J,
Elder JT: Differences in the expression of HLA class I molecules in
skin of uninvolved and lesional psoriatic skin. Journal of Investigative
Dermatology, 127: A435, 2007.
Stoll SW, Gudjonsson JE, Elder JT: Evaluation of candidate ligand
sheddases in psoriatic skin. Journal of Investigative Dermatology, 128:
A840, 2008.
Rittie L, Stoll SW, S. Kang, A. A. Dlugosz, J. J. Voorhees, G. J. Fisher:
Hedgehog signaling maintains hair follicle stem cell phenotype in
young and aged human skin in vivo.
Journal of Investigative
Dermatology, 129: A611, 2009.
Stoll SW, Rittie L, Elder JT: Inhibition of human keratinocyte growth by
amphiregulin-specific shRNA cannot be reversed by EGFR ligands.
Journal of Investigative Dermatology, 129: A573, 2009.
Stoll SW, Rittié L, Elder JT: Amphiregulin carboxyterminal domain is
required for autocrine keratinocyte growth. Journal of Investigative
Dermatology 130: A606, 2010.
Stoll SW, Rittie L, Lambert S, Prasad M, Gudjonsson JE, Li B, Wei Y,
Abecasis G, Stuart PE, Nair RP, Elder JT: Amphiregulin precursor
controls cell-cycle regulatory gene expression in human keratinocytes.
Journal of Investigative Dermatology, 131: A157, 2011.
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Lambert S, Stoll SW, Elder JT: TRAF3IP2 couples IL-17 to the
epidermal defense response. Journal of Investigative Dermatology,
131: A034, 2011.
Stoll SW, Rittié L, Elder JT: HB-EGF directly promotes epithelialmesenchymal transition and invasiveness in human keratinocytes.
Journal of Investigative Dermatology, 132: A160, 2012.
Lambert S, Stoll SW, Elder JT:
IKKi/IKK epsilon mediates
inflammatory induction of DEFB4 in keratinocytes. Journal of
Investigative Dermatology, 132: A071, 2012.
Stoll SW, Rittié L, Lambert S, Johnston A, Swindell WR, Stuart PE,
Elder JT: Amphiregulin cytoplasmic domain regulates G2/M in human
keratinocytes. Journal of Investigative Dermatology, 133: A928, 2013.
Li Y, Talsma C, Stoll SW, Elder JT: Amphiregulin increases
sebaceous gland size and tail epidermal thickness but not basal or
imiquimod-induced skin inflammation.
Journal of Investigative
Dermatology, 133: A903, 2013.
Lambert S, Swindell WR, Tsoi LC, Drumright BL, Stoll SW, Nair RP,
Elder JT: Gene expression signature of TRAF3IP2-silenced
keratinocytes reveals unexpected effects on KC differentiation and
cytokine responses. Journal of Investigative Dermatology, 133: A235,
2013.
Foster AM, Baliwag J, Chen CS, Guzman AM, Stoll SW, Gudjonsson
JE, Ward NL, Johnston A: IL-36 promotes myeloid cell infiltration,
activation and inflammatory activity in skin. Cytokine 63: A262, 2013.
Stoll SW, Rittié L, Lambert S, Johnston A, Swindell WR, Stuart PE,
Elder JT: Amphiregulin supports G2/M progression via FoxM1 and
inhibits differentiation in human keratinocytes. Journal of Investigative
Dermatology, 134: A508, 2014.
C.V. Stefan W. Stoll
December 2014
12