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Dermatology for the Family Physician Student Teaching Session May, 2009 Dr. Laura Lyons St. Joseph’s Family Medical Centre Objectives 1) To review the approach to dermatological complaints in primary care 2) To discuss common dermatological infestations 3) To review frequently encountered viral skin infections 4) To discuss: when to refer, to whom to refer - the multidisciplinary team In Primary Care • • 10 - 15% of clinical work 11,191 patients seen - 2,386 with dermatological concerns - Warts 23% – Benign tumours 16% – Eczema 14% – Infectious 6% – 3% premalignancies, malignancies, acne, psoriasis Julian CG, Dermatology in General Practice, British Journal of Dermatology, 1999;141,51-520 Oh Doctor, just one more thing” “ Approaches in Primary Care 1) Definitive diagnosis - Reassurance Treat as required Refer for treatment (UV-psoriasis) 2) Differential diagnosis - monitor treat for relief/cure = diagnosis procedural diagnosis refer for diagnosis 3) Surveillance/refer for surveillance What’s the Story? Putting the Patient’s Concern in Context Demographics • What is it? What else is there? • Onset, duration, events • Distribution, geography • Any historical triggers or clues • Has it responded to Rx • Bill Longsworth 25 year old male • History of mild asthma and atopic eczema • Recent trip to Punta Cana, spent time in farm region • Seven days ago, on the flight home he began to itch • Other family members similarly affected • Bill’s Rash Infestations Harbouring of insect or worm parasites in or on the body • Worm infestations are rare except in tropical countries • Insect life on the skin is usually transient in temperate climates • Skin Reactions to Infestations Insect Animal ticks Ants, bedbugs, flies Bees, wasps Caterpillars Food and Harvest Mites Lice Mosquitoes Sarcoptes scabei Effect Bites, disease vector Bites Stings Dermatitis Bites Infestation, disease vector Bites, myiasis, disease vector Burrows (scabies), dermatitis Insect Bites Presentation: Uritarica Wheals - papules to Large bulla Cutaneous Reactions: pharmacological irritant allergic Complications: secondary bacterial infection of excoriations Myiasis: parasitic dipterous fly larvae Lice Infestation (pediculosis) Two species Pediculus humanus var capitis and var corporis Phthirus pubis Lice Clinical Presentation Itching of head lice starts at the sides and back of scalp. May develop secondary impetigo • Body lice result in excoriations on the trunk and in chronic infestation, lichenification and pigmentation. These lice are found in the seams of clothes • Pubic lice result in severe itching and secondary eczema and infection • They may involve eyelashes • Scabies Ectoparasitic infection caused by Scarcoptes scabiei var hominis • Cannot be visualized without a microscope upon examination of a scrapping from unexcoriated lesion • Mites burrow in be startum corneum • Pruritis results from a hypersensitivity to the organism • Scabies (continued) Skin lesions are widely scattered macules, papules or pustules, with common findings in the finger webs, axillae, breasts, and genitals • Nodular lesions are a result of epithelial hyperplasia and inflammation • Crusted lesions (Norwegian scabies) are thick crusted or hyperkeratotic infestation by numerous mites, and is often not pruritic • Most commonly seen in immunocompromised patients, neurologically impaired patients and in nursing homes • Scabies Treatment Topical Lotions - repeat after 7 days Permethrin Phenothrin Oral treatment Ivermectin single dose - 150-200mcg/kg Sanitizing bedding and clothing Treat all contacts VIRAL INFECTIONS WARTS Verrucae are common and benign cutaneous tumours due to infection of epidermal cells with human papillomavirus (HPV) • Over 80 subtypes of DNA HPV have been identified • Types 1, 2, and 4 are associated with plantar warts • Types 3 and 10 are common hand warts • Types 6, 11, 16 and 18 are associated with genital warts • The virus infects by direct inoculation and is caught by touch, sexual contact or at the pool (or gym) Immonusuppressed patients are particularly susceptible to viral warts Common Warts - Verrucae vulgares The epidermis is thickenened and hyperkeratotic • Keratinocytes in the granular layer are vacuolated due to being infected with the wart virus • Usually multiple, common on hands and feet but also affect the face and genitalia • Rare in infants, incidence rises in school years. 10% of children between the ages of 2 and 12 have warts. Incidence peak between 12 - 16 • Plantar Warts - Verrucae planae On the soles of the feet, most common in children and adolescents - painful • Pressure causes them to grow into the dermis • Covered in callus, which when pared reveals dark thrombosed capillaries • Mosaic warts are plaques on the soles that comprise multiple individual warts • Genital and Peri-anal Warts Condylomata acuminata Discrete sessile, smooth surfaced papillomas that can be flesh coloured, brown or whitish • They are most commonly found on the external genitalia, perineum and peri-anal areas • Peak incidence between 25 - 45 years of age • Risks for Cervical Cancer GARDASIL is a vaccine indicated in girls and women 9 to 26 years of age for the prevention of cervical cancer, precancerous or dysplastic lesions, and genital warts caused by human papillomavirus (HPV) Types 6, 11, 16, and 18. • Test for HPV • What is this? Molluscum Contagiosum Mainly affects children and young adults Spread by contact including sexual transmission or on towels Clinical Presentation Discrete pearly-pink umbilicated papules a that are caused by a DNA pox virus Dome shaped and a few millimeters in diameter If squeezed releases a cheesy material Usually multiple or grouped, sometimes with localized eczema Untreated they may persist for several months Treatment Options Topical Salicylic and lactic acids Glutaraldehyde Formaldehyde Podophyllotoxin 0.15% cream Imiquimod cream Other Treatments Cryotherapy Curretage and Cautery Laser Surgery Interferon Intralesional Bleomycin It is a cold wet day in early March. Peter Graham, a 57 year old homeless man arrives in your community clinic requesting a prescription for pain medication…. What you observe Peter is limping on the way to the exam room • He looks flushed and fatigued • He sits down while scratching his neck and waist • You notice he has multiple warts on his knuckles • What are your concerns? • Pediculosis corporis Condylomata Immersion Foot To Whom to Refer: The multidisciplinary team - Family physician Dermatologist Rheumatologist Plastic surgeon Pathologist Internist / infectious disease Psychologist / Social Worker Nurse / Wound Care Specialist Community Care Access Centre Vascular surgeon General surgeon Shoppers Home Health Care THE END