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PowerPoint® Lecture Slide Presentation
by Patty Bostwick-Taylor,
Florence-Darlington Technical College
The Nervous
System
7
PART A
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
I can diagram the flow of information through the
nervous system
 Bell Ringer – List the two major divisions of the
nervous system
 Agenda
 BR
 Notes – overview of nervous system
 Lab activity – stimulus response time
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functions of the Nervous System
1. Sensory input—gathering information
 To monitor changes occurring inside and outside the body
 Changes = stimuli
2. Integration
 To process and interpret sensory input and decide if action is
needed
3. Motor output
 A response to integrated stimuli
 The response activates muscles
or glands
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functions of the Nervous System
Figure 7.1
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Classification
of the Nervous System
 Central nervous system (CNS)
 Brain
 Spinal cord
 Peripheral nervous system (PNS)
 Nerves outside the brain and spinal cord
 Spinal nerves
 Cranial nerves
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of
the Peripheral Nervous System
 Sensory (afferent) division
 Nerve fibers that carry information to the
central nervous system
 Motor (efferent) division
 Nerve fibers that carry impulses away from the
central nervous system
 Two subdivisions
 Somatic nervous system = voluntary
 Autonomic nervous system = involuntary
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Organization of the Nervous System
Figure 7.2
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
I can describe the supporting cells of the CNS and
PNS

Sensory Input
 _______________
 Central Nervous system
 ________________
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Support cells in the CNS are grouped together as
“neuroglia”
 Function: to support, insulate, and protect
neurons
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Astrocytes
 Abundant, star-shaped cells
 Brace neurons
 Form barrier between capillaries and neurons
 Control the chemical environment of
the brain
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
Figure 7.3a
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Microglia
 Spiderlike phagocytes
 Dispose of debris
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Ependymal cells
 Line cavities of the brain and spinal cord
 Circulate cerebrospinal fluid
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Oligodendrocytes
 Wrap around nerve fibers in the central
nervous system
 Produce myelin sheaths
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
Figure 7.3d
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells-PNS
 Satellite cells
 Protect neuron cell bodies
 Schwann cells
 Form myelin sheath in the peripheral nervous
system
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
Figure 7.3e
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
I can describe the Anatomy and Physiology of a
Neurons
Bell Ringer – Matching
A. Ependymal cells
B. Oligodentrocytes
C. Astrocytes
D. Microglia
1. Circulate cerebrospinal fluid
2. Spiderlike phagocytes
3. Control the chemical environment of
the brain, brace neurons
4. Produce myelin sheaths in CNS
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Neurons = nerve cells
 Cells specialized to transmit messages
 Major regions of neurons
 Cell body—nucleus and metabolic center
of the cell
 Processes—fibers that extend from the
cell body
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Cell body
 Nissl substance
 Specialized rough endoplasmic reticulum
 Neurofibrils
 Intermediate cytoskeleton
 Maintains cell shape
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
Figure 7.4
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Cell body
 Nucleus
 Large nucleolus
 Processes outside the cell body
 Dendrites—conduct impulses
toward the cell body
 Axons—conduct impulses away
from the cell body
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
Figure 7.4
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Axons end in axonal terminals
 Axonal terminals contain
vesicles with
neurotransmitters
 Axonal terminals are
separated from the next
neuron by a gap
 Synaptic cleft—gap
between adjacent neurons
 Synapse—junction
between nerves
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Myelin sheath—whitish,
fatty material covering
axons
 Schwann cells—produce
myelin sheaths in jelly roll–
like fashion
 Nodes of Ranvier—gaps in
myelin sheath along the
axon
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
Figure 7.5
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Cell Body Location
 Most neuron cell bodies are found in the central
nervous system
 Gray matter—cell bodies and unmyelinated
fibers
 Nuclei—clusters of cell bodies within the white
matter of the central nervous system
 Ganglia—collections of cell bodies outside the
central nervous system
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of Neurons
 Sensory (afferent) neurons
 Carry impulses from the sensory receptors to
the CNS
 Cutaneous sense organs
 Proprioceptors—detect stretch or tension
 Motor (efferent) neurons
 Carry impulses from the central nervous
system to viscera, muscles, or glands
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of Neurons
Figure 7.7
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of Neurons
 Interneurons (association neurons)
 Found in neural pathways in the central
nervous system
 Connect sensory and motor neurons
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Classification
Figure 7.6
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Classification of Neurons
 Multipolar neurons—many extensions from the
cell body
Figure 7.8a
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Classification of Neurons
 Bipolar neurons—one axon and one dendrite
Figure 7.8b
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Structural Classification of Neurons
 Unipolar neurons—have a short single process
leaving the cell body
Figure 7.8c
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Properties of Neurons
 Irritability
 Ability to respond to stimuli
 Conductivity
 Ability to transmit an impulse
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Resting neuron
 The plasma membrane at rest is polarized
 Fewer positive ions are inside the cell than
outside the cell
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Depolarization
 A stimulus depolarizes the neuron’s
membrane
 A depolarized membrane allows sodium (Na+)
to flow inside the membrane
 The exchange of ions initiates an action potential
in the neuron
Figure 7.9a–b
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Action potential
 If the action potential (nerve impulse) starts, it
is propagated over the entire axon
 Impulses travel faster when fibers have a
myelin sheath
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
Figure 7.9c–d
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
 Repolarization
 Potassium ions rush out of the neuron after
sodium ions rush in, which repolarizes the
membrane
 The sodium-potassium pump, using ATP,
restores the original configuration
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulses
Figure 7.9e–f
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
 Impulses are able to cross
the synapse to another nerve
 Neurotransmitter is
released from a nerve’s
axon terminal
 The dendrite of the next
neuron has receptors
that are stimulated by the
neurotransmitter
 An action potential is
started in the dendrite
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Synapse
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Neurotransmitter binds
to receptor
on receiving
neuron’s
membrane
Neurotransmitter is released into
synaptic cleft
Neurotransmitter
molecules
Synaptic cleft
Ion channels
Receiving neuron
Neurotransmitter
broken down
and released
Neurotransmitter
Receptor
Na+
Na+
Ion channel opens
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Ion channel closes
Transmission of a Signal at Synapses
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Synapse
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Neurotransmitter is released into
synaptic cleft
Neurotransmitter
molecules
Synaptic cleft
Ion channels
Neurotransmitter binds
to receptor
on receiving
neuron’s
membrane
Receiving neuron
Neurotransmitter
Receptor
Neurotransmitter
broken down
and released
Na+
Na+
Ion channel opens
Ion channel closes
Figure 7.10
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Synapse
Figure 7.10, step 1
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Synapse
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Synaptic cleft
Ion channels
Receiving neuron
Figure 7.10, step 2
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Synapse
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Synaptic cleft
Ion channels
Neurotransmitter is released into
synaptic cleft
Neurotransmitter
molecules
Receiving neuron
Figure 7.10, step 3
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Synaptic cleft
Ion channels
Neurotransmitter is released into
synaptic cleft
Synapse
Neurotransmitter binds
to receptor
on receiving
neuron’s
membrane
Neurotransmitter
molecules
Receiving neuron
Figure 7.10, step 4
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Transmission of a Signal at Synapses
Axon of
transmitting
neuron
Axon
terminal
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Neurotransmitter is released into
synaptic cleft
Neurotransmitter binds
to receptor
on receiving
neuron’s
membrane
Neurotransmitter
molecules
Synaptic cleft
Ion channels
Synapse
Receiving neuron
Neurotransmitter
Receptor
Na+
Ion channel opens
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 7.10, step 5
Transmission of a Signal at Synapses
Axon
Axon of
terminal
transmitting
neuron
Vesicles
Action
potential
arrives
Synaptic
cleft
Receiving
neuron
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Neurotransmitter is released into
synaptic cleft
Neurotransmitter binds
to receptor
on receiving
neuron’s
membrane
Neurotransmitter
molecules
Synaptic cleft
Ion channels
Synapse
Receiving neuron
Neurotransmitter
Receptor
Na+
Ion channel opens
Neurotransmitter
broken down
and released
Na+
Ion channel closes
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 7.10, step 6
Transmission of a Signal at Synapses
Axon
terminal
Axon of
transmitting
neuron
Action
potential
arrives
Vesicles
Synaptic
cleft
Receiving
neuron
Synapse
Transmitting neuron
Vesicle
fuses with
plasma
membrane
Neurotransmitter is released into
synaptic cleft
Neurotransmitter
molecules
Synaptic cleft
Ion channels
Neurotransmitter binds
to receptor
on receiving
neuron’s
membrane
Receiving neuron
Neurotransmitter
Receptor
Na+
Ion channel opens
Neurotransmitter
broken down
and released
Na+
Ion channel closes
Copyright © 2009 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 7.10, step 7
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