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CNS Sequence CNS Histology March 8, 2010 Spinal cord Dorsal horns: Interneurons Ventral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic (S2-4) neurons DRG: Sensory (pseudounipolar) neurons Autonomic ganglia: Post ganglionic neurons with unmyelinated axons. Sympathetic: paravertebral ganglia Parasympathetic: In organs 65-2 Lumbar Spinal Cord, H&E Dura mater D.R.G. Spinal Cord Myelinated nerves #65-1N Spinal cord and DRG Dorsal horn Lateral horn Ventral horn Dorsal root ganglion (DRG) Dorsal median sulcus 66a Thoracic Spinal Cord Dorsal horn Lateral horn Ventral horn Ventral median fissure 66a Thoracic Spinal Cord Neurons in Lateral Horn Neurons in ventral Horn 65-1N Motor neurons, glial cells and neuropil Glial cells Neuropil Dorsal root ganglion cells Brain Cerebrum Sulcus (sulci) Gyrus (gyri) 3rd ventricle Cerebellum 4th ventricle Pons Medulla oblongata Cerebrum and Cerebellum 76b 77 #77 Cerebellum #76b C: Cortex of gray matter Cerebrum W: White matter C C C W W W #77 Cerebellum Cortex White matter #77 Cerebellum Purkinje neurons (cells) #77a Cerebellar Cortex #76 Cerebrum #76 Cerebral cortex Ross and Pawlina, p.311 Cerebellum Cerebrum C: Cortex of gray matter W: White matter Purkinje cells (neurons) C C Pyramidal cells (neurons) W W Hippocampal Formation Lateral View Posterior View #NP004N Hippocampal region CA: Cornus ammonis Choroid plexus CA2 CA3 Hippocampus CA1 Dentate gyrus 3 layers of Hippocampal region Polymorphic layer Pyramidal cell layer Pyramidal cells 3 layers of Dentate gyrus Molecular layer (dendrites of granule cells) Granule cell layer (neurons) Polymorphic layer Polymorphic layer (interneurons) #74 Sympathetic ganglion cells #75 Parasympathetic ganglion cells Seminal vesicle Sensory and Autonomic Neurons (DRG) (Parasympathetic)