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Chapter 2: Brain and Behavior Neuron and Its Parts • Neuron: Individual nerve cell; 100 billion in brain – Dendrites: Receive messages from other neurons – Soma: Cell body; body of the neuron – Axon: Carries information away from the cell body – Axon Terminals: Branches that link the dendrites and soma of other Figure 2.1 Main Parts of the Neuron Figure 2.2 The Nerve Impulse • Resting Potential: Electrical charge of an inactive neuron • Threshold: Trigger point for a neuron’s firing • Action Potential: Nerve impulse More on Nerves • Ion Channels: Tiny holes through the axon membrane • Negative After-Potential: When a neuron is less willing to fire • Synapse: Microscopic space between two neurons over which messages pass Figure 2.3 Figure 2.4 Neuron and Neural Impulse Windows Mac OS 8-9 Mac OS X Neurotransmitters • Chemicals that alter activity in neurons; brain chemicals – Acetylcholine: Activates muscles – Dopamine: Muscle control – Serotonin: Mood and appetite control • Receptor Site: Areas on the surface of neurons and other cells that are sensitive to neurotransmitters or Normal Synaptic Transmission of Dopamine Synaptic Transmission Windows Mac OS 8-9 Mac OS X Figure 2.6 Neural Regulators • Neuropeptides: Brain chemicals that regulate activity of other neurons – Enkephalins: Relieve pain and stress; similar to endorphins – Endorphins: Released by pituitary gland; also help to relieve pain • Placebos raise endorphin levels Interaction of Endorphins & Opiates Nerves and Neurons • Nerves: Large bundles of axons and dendrites • Myelin: Fatty layer of tissue that coats axons – Multiple Sclerosis (MS) occurs when myelin layer is destroyed; numbness, weakness, and paralysis occur Nerves and Neurons (cont.) • Neurilemma: Thin layer of cells wrapped around axons outside brain and spinal cord; forms a tunnel that damaged fibers can follow as they repair themselves • Neurogenesis: Production of new brain cells; brain loses thousands of cells each day and grows new Neural Networks • Central Nervous System (CNS): Brain and spinal cord • Peripheral Nervous System: All parts of the nervous system outside of the brain and spinal cord Two Divisions of the Peripheral Nervous System • Somatic System: Links spinal cord with body and sense organs; controls voluntary behavior • Autonomic System: Serves internal organs and glands; controls automatic functions such as heart rate and blood pressure Two Divisions of the Autonomic Nervous • Sympathetic:System Arouses body; emergency system • Parasympathetic: Quiets body; most active after an emotional event Figure 2.7 Figure 2.8 Figure 2.9 The Spinal Cord • Spinal Nerves: 31 of them; carry sensory and motor messages to and from the spinal cord • Cranial Nerves: 12 pairs that leave the brain directly without passing through the spinal cord; also work to communicate messages The Spinal Cord and Behavior • Reflex Arc: Simplest behavior in which a stimulus provokes an automatic response • Sensory Neuron: Nerve cell that carries messages from the senses toward the CNS • Motor Neuron: Cell that carries commands from the CNS to the Researching the Brain • Ablation: Surgical removal of tissue • Deep Lesioning: A thin wire electrode is lowered into a specific area inside the brain; Electrical current is then used to destroy a small amount of brain tissue Figure 2.10 Brain Imaging Techniques • Computed Tomographic Scanning (CT): Computer-enhanced X-ray of the brain or body • Magnetic Resonance Imaging (MRI): Uses a strong magnetic field, not an X-ray, to produce an image of the brain and body More Brain Imaging Techniques • Functional MRI (fMRI): MRI that makes brain activity visible • Positron Emission Tomography (PET): Computer-generated color image of brain activity, based on glucose consumption in the brain Figure 2.11 Figure 2.16 Cerebral Cortex • Outer layer of the cerebrum • Cerebrum: Two large hemispheres that cover upper part of the brain • Corticalization: Increase in size and wrinkling of the cortex • Cerebral Hemispheres: Right and left halves of the cerebrum Split Brains • Corpus Callosum: Bundle of fibers connecting cerebral hemispheres • In Split Brains, Corpus Callosum is cut; done to control severe epilepsy (seizure disorder) • Result: The person now has two brains in one body • This operation is rare and is often Figure 2.21 The Corpus Callosum Figure 2.18 Right Brain/Left Brain • Humans use 95 percent of our left brain for language The Left Hemisphere • Left hemisphere is better at math, judging time and rhythm, and coordinating order of complex movements – Processes information sequentially The Right Hemisphere • Right hemisphere is good at perceptual skills, and at expressing and detecting other’s emotions – Processes information simultaneously Figure 2.20 Figure 2.30 Central Cortex Lobes • Areas bordered by major grooves or fissures or defined by their functions • Occipital Lobe: Back of brain; vision center • Parietal Lobe: Just above occipital; bodily sensations such as touch, pain, and temperature The Occipital Lobe The Parietal Lobe The Last Two Lobes • Temporal Lobe: Each side of the brain; auditory and language centers • Frontal Lobe: Movement, sense of smell, higher mental functions – Contains motor cortex; controls motor movement Figure 2.23 The Temporal Lobe The Frontal Lobe Figure 2.24 When the Brain Fails to Function Properly • Association Cortex: All areas of the cerebral cortex that are not primarily sensory or motor in function • Aphasia: Speech disturbance resulting from brain damage Broca’s Area • Language area related to grammar and pronunciation – If damaged, person knows what s/he wants to say but can’t say the words Wernicke’s Area • Wernicke’s Area: Related to language comprehension; in left temporal lobe – If damaged, person has problems with meanings of words, NOT pronunciation Figure 2.28 Subcortex • All brain structures below cerebral cortex; immediately below cerebral hemispheres • Hindbrain (Brainstem) • Medulla: Connects brain with the spinal cord and controls vital life functions such as heart rate and breathing More Subcortex Structures • Pons (Bridge): Acts as a bridge between brainstem and other structures; influences sleep and arousal • Cerebellum: Located at base of brain; regulates posture, muscle tone, and muscular coordination The Brainstem Subcortex: Reticular Formation (RF) • Reticular Formation: Inside medulla and brainstem – Associated with alertness, attention, and some reflexes (breathing, coughing, sneezing, vomiting) • Reticular Activating System (RAS): Part of RF that activates cerebral cortex – Its alarm clock Forebrain • Structures are part of Limbic System: System within forebrain closely linked to emotional response and motivating behavior • Thalamus: Relays sensory information on to the cortex; switchboard • Hypothalamus: Regulates More Forebrain Structures • Amygdala: Associated with fear responses • Hippocampus: Associated with storing permanent memories; helps us navigate through space The Limbic System Figure 2.27 Figure 2.26 Endocrine System • Glands that pour chemicals (hormones) directly into the bloodstream or lymph system • Pituitary Gland: Regulates growth via growth hormone Pituitary Problems • Too little means person will be smaller than average – Hypopituitary Dwarfs: As adults, perfectly proportioned but tiny – Treatable by using growth hormone; will add a few inches – Treatment is long and expensive Endocrine System (cont.) • Too much growth hormone leads to giantism (excessive body growth) • Acromegaly: Enlargement of arms, hands, feet, and facial bones; due to too much growth hormone released late in growth period – Andre the Giant • Pituitary also governs functioning of Figure 2.29 The Pineal Gland • Regulates body rhythms and sleep cycles – Releases hormone melatonin, which responds to daily variations in light The Thyroid Gland • Thyroid: In neck; regulates metabolism – Hyperthyroidism: Overactive thyroid; person tends to be thin, tense, excitable, nervous – Hypothyroidism: Underactive thyroid; person tends to be inactive, sleepy, slow, obese The Adrenal Glands • Adrenals: Arouse body, regulate salt balance, adjust body to stress, regulate sexual functioning; located on top of kidneys – Releases epinephrine and norepinephrine (also known as adrenaline and noradrenalin) The Adrenal Glands (cont.) • Adrenal Medulla: Source of epinephrine and norepinephrine • Adrenal Cortex: Produces hormones known as corticoids – Regulate salt balance – Deficiency in some types will cause powerful salt cravings in humans Adrenal Hormones • Epinephrine arouses body; is associated with fear • Norepinephrine arouses body; is linked with anger Adrenal Problems • Oversecretion of adrenal sex hormones can cause virilism: exaggerated male characteristics (Bearded woman) – May also cause premature puberty if occurs early in life Figure 2.31 Handedness • Preference for right or left hand in most activities • Dominant Hemisphere: Term usually applied to the side of the human brain that produces language • Lateralization: Specialization in abilities of brain hemispheres