Download Coding in the CNS

Structure and functions of cells of the nervous
system
Chapter 2
Localization of brain functions:
System approach
Gall
Brocka, Wenicke
Brain functions:
The neuron approach
Neuron is the basic computational
unit:
Input - synapse.
Analysis – integrate and fire.
Output – synapse. 12/11/06
Brain and basic functions:
The reflexes
Communication between neurons
Arousal system wakes up
the rest of the brain
Divergence
‫ביזור‬
Integration of sensory modalities
to a common concept
Convergence
‫התלכדות‬
How neurons decode the signal?
The brain contains a network of ~ 1010 interconnected
neurons. In every small volume of cortex, thousands of spikes
are emitted each millisecond. What is the information
contained in such spatio-temporal pattern of pulses?
What is the code used by the
neurons to transmit that
information? How might
other neurons decode the
signal?
Coding in the CNS
Integration in the neuron
Measuring the potential of a neuron
Stimulation and
recording of a neuron
Action potential
Relative concentration of ions inside and
outside of the neurons
Sodium-potassium pump
Ion movements
during action
potential
Membrane permeability during action potential
Conductance of action potential
Coding in the CNS
Decremental conduction
Saltatory conduction
Synaptic variations
Details of the
synapse
EM of a synapse
Release of neurotransmitter
Release of
neurotransmitter
Recycling of the membrane
Ionotropic
receptors
Metabotropic receptors
Ionic movement during postsynaptic potentials
Reuptake of the neurotransmitter
END