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Creutzfeld Jakob Disease Alexia Constanza Espiño Álvarez What’s CJD? •CJD is a form of brain damage that causes a rapid decrease of mental function and movement. •CJD is believed to result from a protein called a prion. •CJD can beare grouped intotypes classicofor new •There several variant disease. CJD. The disorder is rare, The occurring classic types of CJD1are: in about out of 1 million CJD people. It usually first cases. It Sporadic makes up the most between ages 20 oftenappears occurs for no known reasons. and 70, with average age and Familial CJD results when a person the symptoms start in the late inherited 50s. the abnormal protein (prion). This type is rare. The new variant CJD (nvCJD) is an infectious form that is related to mad cow disease Symptoms Here is a list of some of the common signs and symptoms of Creutzfeldt Jakob Disease: -Muscle weakness on one side of body -Blindness -Muscular coordination problems -Confusion -Mutism -Decreased abdominal reflexes -Dementia -Personality changes -Progressive muscular atrophy -Depression -Rapid involuntary eye movements -Disorientation -Rigidity -Hallucinations -Insomnia -Involuntary movements -Sensory disturbances -Speaking difficulty -Memory failure -Tremor -Mental deterioration -Unusual sensations Diagnosis Tests used to diagnose this condition may include: A neurological and motor system examination shows muscle spasm. -EEG : electroencephalogram. EEG: There -Spinal tapis loss of coordination related to visual-spatial electroencephalogram perception changes and changes in the cerebellum, the area the brain controls coordination. Ultimately, theof disease can that only be confirmed by brain biopsy or autopsy. An eye examination shows areas of blindness. Lumbar Spinal Tap Treatment Here is a list of treatments and procedures that are commonly used to treat Creutzfeldt Jakob Disease: -Blood Transfusion. There is no known cure. -Clonazepam: a highly potent anticonvulsant and muscle relaxant. -Deep Brain Stimulation. Medications may be needed to control -Opiate drugs. aggressive behaviors, like: sedatives, antipsychotics… -Sodium valproate: an anticonvulsant, •Also, controlling aggressive or agitated behavior, and meeting physiologist, support from the family may be good for people with CJD. Prevention To reduce the already very low risk of CJD transmission people should never donate blood, tissues, or organs if they have suspected or confirmed. Most countries now have strict guidelines for management of infected cows and strict restrictions regarding what they are fed, to avoid the potential for transmission of CJD to humans. What research is taking place? Many researchers are studying CJD They are investigating how CJD can be transmitted and how it damages the brain. They want to know the development of this disorder to find treatments and a effective cure News Blood test for vCJD 'unrealistic' In Jaffrey, a woman’s death is probed Former Buffalo mayor died from brain disease CJD 14 cases of 'mad cow disease' found in NI A video about CJD