Download inflammation & degeneration arthritis

INFLAMMATION & DEGENERATION
ARTHRITIS
DEFINITIONS
INFLAMMATORY JOINT DISEASE IS SYSTEMIC,
CAUSES STIFFNESS ALL OVER, SWELLING IN
JOINTS, PAIN AND FATIGUE
DEGENERATIVE JOINT DISEASE CAUSES PAIN
WITH MINIMAL STIFFNESS AND SWELLING
AND NO FATIGUE
DIFFERENCE
STIFFNESS IS FAR GREATER IN
INFLAMMATORY ARTHRITIS THAN
DEGENERATIVE AND SO IS THE
FATIGUE/WEAKNESS
ETIOLOGY
INFLAMMATORY IS AUTOIMMUNE (RA,
LUPUS), CRYSTAL INDUCED (GOUT),
INFECTIOUS, METABOLIC
(THYROID,PARATHYROID)
DEGENERATIVE IS GENETIC, END RESULT OF
INFLAMMATORY, TRAUMA, AGE...
CASE - 1
80 YEAR OLD WITH MODERATELY SEVERE
BACK PAIN AFTER WALKING LESS THAN A MILE,
SHE ALSO IS STIFF IN HANDS FOR 45 MIN IN AM
CASE - 2
45 YO WITH GENERALIZED SEVERE PAIN, IN ALL
JOINTS AND STIFFNESS THAT LASTS FOR HRS.
AFTER TREATMENT HER DEVELOPED
INCREASING LEFT HIP PAIN THAT IS
PROGRESSIVELY GETTING WORSE.
TREATMENT
HISTORY AND PHYSICAL
LAB
X-RAY/MRI
TREATMENT
PHYSICAL THERAPY
AQUA-THERAPY
FISH OIL/GLUCOSAMINE
EXERCISE
TOPICAL APPLICATIONS
TREATMENT
GLUTEN FREE
MSG, ALFALFA SPROUTS
MEAT, SEA FOOD, BBQ,
COOKED TOMATOES AND EGGPLANTS
ALCOHOL- BEER VERSUS OTHERS
TREATMENT
NSAIDs
DISEASE MODIFYING DRUGS-NON BIOLOGICS
DISEASE MODIFYING DRUGS-BIOLOGICS
RESEARCH
TREATMENT
NON BIOLOGICS EXAMPLES: MTX, SULFA,
LEFLUNOMIDE, PLAQUENIL (HCQ),
AZATHIOPRINE, CELLCEPT...
TREATMENT
TNF BIOLOGICS: ENBREL, HUMIRA,
REMICADE, CIMZIA, SIMPONI, ARIA
TREATMENT
NON-TNF: ORENCIA, RITUXAN, ACTEMRA,
BENLYSTA, XELJANZ,
TREATMENT
HIGH RISK MEDS: EDUCATE, SCREEN,
VACCINE, HYGENE