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Transcript 
gp120
env
gp41
p17
gag
p24
RNA genome
Integrase
Protease
Reverse transcriptase (RT)
The HIV virus
pol
Committee on Oversight and Government Reform. HIV/AIDS Today, 1(1):1, January 18, 2008
UNAIDS Global Report, 2012
UNAIDS Global Report, 2010
Percent of adults (15+) living with HIV who are female,
1990–2007
70
Sub-Saharan Africa
GLOBAL
Caribbean
Asia
E Europe & C Asia
Latin America
60
50
Percent
40
female
(%)
30
20
10
0
5
1990‘91 ‘92 ‘93 ‘94 ‘95 ‘96 ‘97 ‘98 ‘99 ‘00 ‘01 ‘02 ‘03 ‘04 ‘05 ‘06 2007
Year
The HIV/AIDS Epidemic in the U.S.
through 2011
Kaiser Family Foundation. Black Americans and HIV/AIDS. Fact Sheet, March 2013
Kaiser Family Foundation. Black Americans and HIV/AIDS. Fact Sheet, March 2013
El-Sadr WM, Mayer KH,
Hodder SL. AIDS in America Forgotten but not gone. NEJM
362(11):969, 2010.
El-Sadr WM, Mayer KH,
Hodder SL. AIDS in
America - Forgotten but not
gone. NEJM 362(11):968,
2010.
The HIV/AIDS Epidemic in
California
California Department of Health
Services, Office of AIDS, HIV/AIDS
Case Registry Section, Dec 2012
The HIV/AIDS Epidemic in Los
Angeles
County of Los
Angeles Public
Health. 2010
Annual HIV
Surveillance
Report, Jan 2011
County of Los Angeles Public Health. 2011 Annual HIV Surveillance Report
County of Los Angeles Public Health. 2011 Annual HIV Surveillance Report
County of Los Angeles Public Health. 2011 Annual HIV Surveillance Report
County of Los Angeles Public Health. HIV/AIDS Semi-Annual Surveillance Summary
County of Los Angeles Public Health. 2011 Annual HIV Surveillance Report
For males only –
HIV not in top 10
causes of
premature death
of women
http://publichealth.lacounty.gov/dca/data/documents/2009MortalityReport.pdf
CDC CLASSIFICATION OF HIV
DISEASE
Group I: Acute infection
Group II: Asymptomatic infection
Group III: Persistent generalized lymphadenopathy
Group IV: Other diseases
CDC CLASSIFICATION OF HIV
DISEASE (continued)
Group IV: Other diseases
Subgroup A: Constitutional disease
Subgroup B: Neurologic disease
Subgroup C: Secondary infectious disease
Subgroup D: Secondary cancers
Subgroup E: Other conditions
APPENDIX B. Conditions included in the 1993 AIDS surveillance case definition (CDC)
Candidiasis of bronchi, trachea, or lungs
Candidiasis, esophageal
Cervical cancer, invasive *
Coccidioidomycosis, disseminated or extrapulmonary
Cryptococcosis, extrapulmonary
Cryptosporidiosis, chronic intestinal (greater than 1 month's duration)
Cytomegalovirus disease (other than liver, spleen, or nodes)
Cytomegalovirus retinitis (with loss of vision)
Encephalopathy, HIV-related
Herpes simplex: chronic ulcer(s) (greater than 1 month's duration); or bronchitis, pneumonitis, or esophagitis
Histoplasmosis, disseminated or extrapulmonary
Isosporiasis, chronic intestinal (greater than 1 month's duration)
Kaposi's sarcoma
Lymphoma, Burkitt's (or equivalent term)
Lymphoma, immunoblastic (or equivalent term)
Lymphoma, primary, of brain
Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary
Mycobacterium tuberculosis, any site (pulmonary * or extrapulmonary)
Mycobacterium, other species or unidentified species, disseminated or extrapulmonary
Pneumocystis carinii pneumonia
Pneumonia, recurrent *
Progressive multifocal leukoencephalopathy
Salmonella septicemia, recurrent
Toxoplasmosis of brain
Wasting syndrome due to HIV
Added in the 1993 expansion of the AIDS surveillance case definition .
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