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Chapter 20 Childhood Diseases and Disorders Copyright © 2015 Cengage Learning®. Infectious Diseases • Four categories: – – – – Viral Bacterial Fungal Parasitic • Some infections can be prevented by immunization Copyright © 2015 Cengage Learning®. Infectious Diseases • Many have incubation period • Symptoms: – – – – – – Fever Malaise Coughing Anorexia Nausea and vomiting Rash Copyright © 2015 Cengage Learning®. Infectious Diseases • Treatment varies with the disease • Often consists of: – – – – – Symptom relief Good nutrition Rest Nonaspirin antipyretics Good hand washing Copyright © 2015 Cengage Learning®. Viral Diseases • Usually symptomatic treatment • Invade host and can lay dormant • Reactivated by certain triggers such as stress Copyright © 2015 Cengage Learning®. Viral Diseases • Measles – – – – Also known as rubeola One of the most serious childhood diseases Commonly spread by contaminated airborne droplets Symptoms: • • • • Fever Runny nose Red maculopapular rash Koplik’s spots Copyright © 2015 Cengage Learning®. Measles/Rubeola Photo courtesy the Centers for Disease Control and Prevention Copyright © 2015 Cengage Learning®. Koplik’s Spots Photo courtesy the Centers for Disease Control and Prevention Copyright © 2015 Cengage Learning®. Viral Diseases • Rubella – Type of measles • Also known as German measles • In pregnant women may lead to birth defects • Less contagious than rubeola – Symptoms: • Lymph node enlargement, nasal discharge, joint pain, chills, fever – Children and women of childbearing age should be immunized Copyright © 2015 Cengage Learning®. Rubella Rash Photo courtesy the Centers for Disease Control and Prevention Copyright © 2015 Cengage Learning®. Viral Diseases • Mumps – Inflammation of parotid glands – Symptoms: • • • • Chills Fever Ear pain Swelling of parotid glands – Complication: • Orchitis and nerve conduction deafness Copyright © 2015 Cengage Learning®. Mumps Photo courtesy the Centers for Disease Control and Prevention Copyright © 2015 Cengage Learning®. Viral Diseases • Varicella – Also known as chickenpox or herpes zoster – Highly contagious – Symptoms: • Classic rash that develops into vesicles • Rash on face, trunk, and extremities • Poliomyelitis – Causes: • Polio virus – Immunization has reduced threat of disease Copyright © 2015 Cengage Learning®. Varicella Photo courtesy Robert A. Silverman, MD, Pediatric Dermatology, Georgetown University Copyright © 2015 Cengage Learning®. Viral Diseases • Influenza – Acute infectious respiratory disease – Occurs late fall through early spring – Symptoms: • Sudden high fever • Dry, hacking cough • Chills, headache, joint or muscle aches – Prevention: • Vaccination Copyright © 2015 Cengage Learning®. Viral Diseases • Common cold – Most frequently occurring disease – Causes: • Rhinovirus – Prevention: • Good hand washing Copyright © 2015 Cengage Learning®. Viral Diseases • Mononucleosis – Primarily affects children and young adults – Causes: • Epstein-Barr virus – Symptoms: • Fatigue, sore throat, fever, swollen lymph glands Copyright © 2015 Cengage Learning®. Viral Diseases • AIDS (covered in detail in Chapter 5) • Has now affected thousands of children • Cause: – HIV • Most cases result from maternal–fetal transfer • Children suffer symptoms and often are orphaned • Treatment: – Treatment focuses on prevention Copyright © 2015 Cengage Learning®. Bacterial Diseases • Causes: – Pathogens • E.g., Staphylococcus, Streptococcus, Haemophilus, Clostridium • Symptoms: – – – – – Cough Fever Headache Difficulty breathing Sore throat • Treatment based on causative agent Copyright © 2015 Cengage Learning®. Bacterial Diseases • Pertussis – Also known as whooping cough – Symptoms: • Catarrhal • Paroxysmal spasm • Violent whooping coughing • Diphtheria – Severe inflammation of respiratory system – Was a leading cause of death in children – Rarely seen now due to vaccination Copyright © 2015 Cengage Learning®. Bacterial Diseases • Tuberculosis – Most commonly affects the respiratory system • But can be systemic to bone, brain, lymph nodes – Increasing number of cases in children • Tularemia – Also known as rabbit fever – Transmitted by bite of infected insect or direct contact with infected animal – Prevention is avoiding tick bites Copyright © 2015 Cengage Learning®. Bacterial Diseases • Impetigo – Contagious superficial pyoderma – Causes: • Staphylococcus • Group A Streptococcus – Prevention: • Good hand washing Copyright © 2015 Cengage Learning®. Bacterial Diseases • Acute tonsillitis – Infection of palatine tonsils located on posterior wall of nasopharynx – Cause: • Commonly group A beta-hemolytic streptococci – Symptoms: • Sore throat • Enlarged tonsils – Treatment: • Antibiotics • Tonsillectomy Copyright © 2015 Cengage Learning®. Bacterial Diseases • Otitis media – Acute bacterial infection of middle ear – Untreated, chronic infection develops – Symptoms: • Pain, fever, ear drainage – Treatment: • Antibiotics • Myringotomy with tympanoplasty Copyright © 2015 Cengage Learning®. Fungal Diseases • Affect skin or mucous membranes in children – Sometimes more common in infants • Usually not severe – But irritating • May need medical attention to prevent spread Copyright © 2015 Cengage Learning®. Fungal Diseases • Candidiasis – Also known as a yeast infection • Common in infants’ mouths and called thrush • In diaper area, called diaper rash – Cause: • Oral fungal infection – Prevention: • Thrush can be prevented by breast feeding; common in infants • Diaper rash treated by keeping the area clean and dry Copyright © 2015 Cengage Learning®. Fungal Diseases • Tinea (discussed in detail in Chapter 18) – Also known as ringworm – Group of diseases • Tinea capitis – Scalp • Tinea pedis – Feet • Tinea cruris – Groin and scrotum Copyright © 2015 Cengage Learning®. Parasitic Diseases • Caused by organism that feeds on another organism • Mostly found in places of poor nutrition, contaminated water, and low socioeconomic conditions • Only a few common in United States Copyright © 2015 Cengage Learning®. Parasitic Diseases • Giardiasis – Infection by caused by protozoa called Giardia lamblia – Young children are most often affected – Protozoa lodge in lining of the small intestine – Symptoms: • • • • Diarrhea Nausea Cramping Flatulence Copyright © 2015 Cengage Learning®. Parasitic Diseases • Pediculosis – Infestation with lice – Transmitted human to human by direct contact – Nits • Lice eggs – Epidemic among school children – Treatment with permethrin (more information in Chapter 18) Copyright © 2015 Cengage Learning®. Parasitic Diseases • Pinworms – Parasitic nematodes that infect intestines and rectum – Transmitted by ingestion or inhalation of eggs – Symptoms: • Anal itching; worms appear as tiny white threads • Roundworms – – – – Found in soil Parasites lodge in intestines Spread by hand-to-mouth activity Absorb nutrients from host Copyright © 2015 Cengage Learning®. Respiratory Diseases • Most common childhood diseases seen by physicians – Children very vulnerable due to continuous person-toperson contact • Infants most susceptible Copyright © 2015 Cengage Learning®. Respiratory Diseases • Sudden infant death syndrome (SIDS) – Abrupt, unexplained death of infant under age 1 – Symptom: • Only symptom is death of unknown cause in an infant • Croup (laryngotracheobronchitis) – Upper respiratory infection – Affects children ages 3 months to 3 years – Symptoms: • Inspiratory stridor Copyright © 2015 Cengage Learning®. Respiratory Diseases • Adenoid hyperplasia – Enlargement of pharyngeal tonsils – May require adenoidectomy • Asthma – Serious chronic respiratory disease in children – Symptoms: • Acute coughing, wheezing, shortness of breath – Cause: • Unknown – Triggers: Stimuli that cause attack Copyright © 2015 Cengage Learning®. Respiratory Diseases • Pneumonia – Infection of lung parenchyma – Symptoms: • • • • Cough Fever Wheezing Malaise – Treatment: • Antibiotics if bacterial • If viral, runs course in 5-7 days Copyright © 2015 Cengage Learning®. Digestive Diseases • Children may experience serious development problems due to lack of appropriate ingestion, digestion, absorption, or elimination • Fluid and electrolyte imbalance frequently more severe in children • May be caused by vomiting and diarrhea • Colic is a common symptom of digestive problems – Gastrointestinal pain, crying, irritability Copyright © 2015 Cengage Learning®. Digestive Diseases • Fluid imbalances – Vomiting or diarrhea can be serious – Dehydration • Life-threatening in children • Food allergies – – – – Most often in children under age 1 Most common allergies are cow’s milk and eggs Many disappear after age 5 If allergy develops after age 3, it usually continues into adult life Copyright © 2015 Cengage Learning®. Digestive Diseases • Eating disorders – Major problem among children • Especially adolescent females – Most common types: • Anorexia nervosa • Bulimia (discussed in detail in Chapter 21) Copyright © 2015 Cengage Learning®. Cardiovascular Diseases • Most cardiovascular diseases in children are related to genetic or developmental disorders (discussed in detail in Chapter 19) Copyright © 2015 Cengage Learning®. Musculoskeletal Diseases • Common in children due to high activity level • Range from soft tissue injuries and fractures to joint and bone deformities or degenerative muscle disorders Copyright © 2015 Cengage Learning®. Musculoskeletal Diseases • Legg-Calvé-Perthes (LCP) – Avascular necrosis of upper end of femur – Causes changes in bone growth – Untreated, it may lead to permanent deformity • Ewing’s sarcoma – Malignant neoplasm occurring before age 20 • Usually in long bones – More common in males – Quickly metastatic and highly malignant Copyright © 2015 Cengage Learning®. Blood Diseases • Leukemia – Malignancy of blood-forming cells in bone marrow – Most common disorder of blood and blood-forming organs in children – Symptoms: • Pallor, bleeding or bruising, fatigue, joint/bone/abdominal pain – Treatment: • Among the most curable diseases of childhood cancers • Chemotherapy Copyright © 2015 Cengage Learning®. Neurologic Diseases • Reye’s syndrome – Acute encephalopathy in children under age 15 who have had viral infection – Cause: • Unknown, there is a relationship between the disease and use of aspirin for febrile illnesses in children – Symptoms: • • • • Nausea and vomiting Liver enlargement Lethargy Seizures, coma, and in many cases death Copyright © 2015 Cengage Learning®. Eye and Ear Diseases • Have profound effects on child’s ability to learn and develop • Strabismus – Lazy or cross-eye • Deafness – Causes: • • • • Genes Trauma Infections Exposure to ototoxic drugs Copyright © 2015 Cengage Learning®. Trauma • Child abuse – Serious problem in United States – Often fatal – Emotional, physical, or sexual harm or neglect • Emotional abuse harder to diagnose than physical abuse • Sexual abuse occurring in epidemic proportions • Suicide – Third leading cause of death among young people – Prevention • Early intervention most important Copyright © 2015 Cengage Learning®. Trauma • Drug abuse – Illicit drug, alcohol, and tobacco use – Epidemic problem among children • Especially adolescents • Poisoning – Among top five causes of accidental death under age 10 – Most poisonings due to common substances found at home • E.g., cleaning products, medicines, plants Copyright © 2015 Cengage Learning®.