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					Chapter Fifteen Sexually Transmitted Infections and HIV/AIDS Agenda  Discuss Attitudes and STIs  Review Information about Sexually Transmitted Infections  Discuss Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS)  Review Cross-Cultural Aspects of AIDS  Discuss Preventing STIs and AIDS Introduction  Over 65 million people in the U.S. are living with an incurable STI  19 million STI infections occur each year, half to those to people 15-24 years old  There are more than 25 infections that spread mainly through sexual activity Design a Campaign  You have been chosen to develop a campaign aimed at developing healthy sexuality for high school students.  In this particular city the rate of STIs is the highest in the country.  Develop the components of your ad campaign.  Present your campaign plan to class. Self Reflection Exercise Do NOT discuss. Write down your thoughts privately. If I found out I was infected with herpes or genital warts, I would … If my partner were infected with chlamydia, I would … If I found out I had AIDS, I would … Attitudes about Sexually Transmitted Infections Attitudes and the STI Epidemic  STIs have been viewed as a sign of corrupt sexuality  Punishment concept of disease – that a person got what they deserved  Negative beliefs and stigma about STIs currently exist These negative attitudes can interfere with getting tested for an STI Attitudes and the STI Epidemic  College students believe they are immune to STIs and engage in high-risk sexual behaviors e.g. multiple partners, unprotected intercourse  2/3 of STIs occur in people under 25 Sexually Transmitted Infections: Trends Reporting Pregnancy Complications Protection Reporting Issues  All states must report syphilis, gonorrhea, chancroid, chlamydia, HIV, & AIDS cases  Many states require that genital warts and herpes be reported  Women are more susceptible to gonorrhea, chlamydia, HIV  Women have more risk of complications from STIs because vaginal tissue is fragile  Women are more likely to be asymptomatic Pregnancy Complications  STIs can affect pregnancies  30-40% of preterm births and infant deaths are due to STIs  Some can cross the placenta (syphilis, HIV)  Some can infect the newborn during delivery (chlamydia, gonorrhea, herpes, HIV)  HIV can be transmitted through breastfeeding  Antibiotics and c-sections can minimize harm Protection  Barrier methods can decrease the risk of STIs  Non-oxynol 9 may increase the risk of infection by irritating the skin  Condoms are the most effective contraceptive that reduces the STI risk  Condoms cannot cover all of the penis, vulva, or scrotum Protection: Partner Issues  Most effective way of avoiding STIs is to abstain from oral, vaginal, and anal sex or be in a long-term, mutually monogamous relationship with someone free from STIs  If a person does have an STI, treatment should include treatment of their sexual partner(s) Class Exercise: Condom Line Up  Penis becomes erect  Carefully open package and remove condom  Buy/Get condoms  Store condoms in cool, dry place  Check expiration date  Decide with partner to have sexual intercourse  Check to see which way condom unrolls  Talk about protection and safer sex  Lose erection  Pull back foreskin if uncircumcised  Place condom on head of penis  Orgasm and ejaculation  Gently squeeze air out of tip of condom  Roll condom all the way down erect penis  Intercourse  Throw away condom in garbage – don’t flush  Hold condom at base of penis and withdraw penis  Remove condom from penis  Lose erection 1. Decide with partner to have sexual intercourse 2. Talk about protection and safer sex 3. Buy/Get condoms 4. Store condoms in cool, dry place 5. Check expiration date 6. Penis becomes erect 7. Carefully open package and remove condom 8. Check to see which way condom unrolls 9. Lose erection 10. Pull back foreskin if uncircumcised 11. Place condom on head of penis 12. Gently squeeze air out of tip of condom 13. Roll condom all the way down erect penis 14. Intercourse 15. Orgasm and ejaculation 16. Hold condom at base of penis and withdraw penis 17. Remove condom from penis 18. Lose erection 19. Throw away condom in garbage – don’t flush Sexually Transmitted Infections Ectoparasitic Infections Bacterial Infections Viral Infections Ectoparasitic Infections  Parasites that live on the skin’s surface  Two sexually transmitted varieties: Pubic Lice Scabies Pubic Lice  Also called “crabs”  Small, wingless insects that are difficult to detect on light-skinned people  Attach to pubic hair (preferred) by their claws & drink from tiny blood vessels under the skin  Cannot survive more than 24 hours off of the body, however, they reproduce rapidly and eggs are cemented to the hair  Highly contagious Pubic Lice: Prevalence, Symptoms, Treatment  Incidence: common  Symptoms: mild to severe itching (particularly at night) thought to be due to allergic reaction from their saliva  Diagnosis: lice and eggs are visible  Treatment: kill eggs & lice with Kwell ointment (shampoo, cream); clothing & sheets dry cleaned, boiled, or washed in hot water Scabies  Mite Sarcoptes scabiei  Spread via any skin-to-skin contact  Mites can live up to 48 hours off of the body  Not visible to naked eye Scabies: Prevalence, Symptoms, Treatment  Incidence: millions worldwide  Symptoms: rash and severe itching  Diagnosis: examination of the rash and a skin scraping can confirm diagnosis  Typically less than 10 mites on the body during an infection  Treatment: topical creams; clothing and sheets washed in hot water Bacterial Infections  Gonorrhea  Syphilis  Chlamydia and Nongonococcal Urethritis  Chancroid  Vaginal Infections  Pelvic Inflammatory Disease Gonorrhea  Also called the “clap” or “drip”  Survives only in mucous membranes, such as the cervix, mouth, urethra, rectum, throat, eyes  Transmitted when mucous membranes contact each other  Incidence: second most commonly reported infectious disease in the U.S.; 600,000 to 1 million new cases each year Gonorrhea: Symptoms  Women: most are asymptomatic, cervix is most common infection site; urinary frequency, abnormal bleeding  Men: 25% are asymptomatic; epididymitis, urethral discharge, painful, frequent, & urgent urination  Swelling, pain, & pus in the joints  Rectal gonorrhea: bloody stools & pus Gonorrhea: Diagnosis & Treatment  Diagnosis: examine for bacteria in a sample of the discharge; can also run DNA testing of urine  Treatment: antibiotics (oral, injection) Note: there are rare cases when they have become drug-resistant Syphilis  Live in the mucous membranes  Typically first infects the cervix, anus, penis, lips, or nipples  Incidence: 7,177 cases reported in 2003  Symptoms: 3 stages Primary/Early Secondary (after chancres disappear) Tertiary (remission, but still infectious; can lead to long term health risks) Syphilis: Stage 1 1: primary/early syphilis 10-90 days after infection Chancres (small, round, red-brown, painless sores with a hard raised edge & sunken center) may appear on the vulva, penis, vagina, cervix, anus, mouth, lips Syphilis: Stage 2 2: secondary syphilis after chancres disappear Syphilis invades the central nervous system Reddish patches on the skin, possible wart-like growths in area of infection Lymph glands enlarge Headaches, fever, anorexia, flu-like symptoms, fatigue Syphilis: Stage 3 3: tertiary/late syphilis Stage of remission and a person feels fine, though able to transmit the disease for 1 year If not treated, this stage can cause neurological, muscular, sensory, & psychological difficulties and is eventually fatal Syphilis: Diagnosis & Treatment  Diagnosis: culture taken from a lesion; blood tests  Treatment: Penicillin; antibiotics can temporarily increase the symptoms for a few hours Chlamydia and Nongonococcal Urethritis  May also cause epididymitis and nongonococcal urethritis in men  Incidence: most commonly reported infectious disease in the U.S.; estimated 2.8 million new cases per year Highest among African Americans Higher in young women Underdiagnosed in men Chlamydia and Nongonococcal Urethritis: Symptoms  Chlamydia is highly contagious  Symptoms: asymptomatic in 75% of women and 50% of men Female symptoms: burning while urinating, painful intercourse, pain in lower abdomen, bleeding/spotting, rare for discharge 40% will get PID, 20% will become infertile Male symptoms: discharge from penis, burning while urinating, burning & itching at penile opening, pain or swelling of testicles Chlamydia and Nongonococcal Urethritis: Diagnosis & Treatment  Diagnosis: culture cervical discharge for women, blood test, urine test for men  Treatment: antibiotics for 7-10 days; some cases have become drug-resistant Vaginal Infections  There are many common vaginal infections related to sexual intercourse Trichomoniasis Bacterial vaginosis Candiasis Trichomoniasis  Trichomonas vaginalis  Female symptoms 3-28 days after infection: increase in yellowish, frothy, & foul-smelling vaginal discharge; burning/itching in vagina; asymptomatic  Male symptoms: asymptomatic, discharge at tip of penis, burning while urinating or ejaculating  Treatment: metronidazole (Flagyl™) Bacterial Vaginosis  Most common vaginal infection in women of childbearing age, though half are asymptomatic  Increased susceptibility with: multiple partners, douching, low concentrations of beneficial vaginal bacteria  Treatment: metronidazole or clindamycin Candidiasis  Vulvovaginal candiasis; yeast infection  Caused by a variety of fungi, most commonly Candida albicans  Fungi normally common in vagina, but will multiply when the pH balance is disturbed  pH changes due to: pregnancy, oral contraceptives, douching, antibiotics, diabetes, fecal material contacting the vagina Candidiasis  Symptoms: burning, itching, and increase in vaginal discharge that may be thin, white, and including white chunks  75% of women will have at least one yeast infection  Recurrences are common  Treatment: antifungal prescription or over-thecounter drugs (cream is topical or inserted into the vagina); plain yogurt Pelvic Inflammatory Disease  Infection of the female genital tract  Most often caused by chlamydia and gonorrhea  PID can cause long-term complications such as ectopic pregnancies, chronic pelvic pain, infertility  Estimated to affect 1 out of 7 women by age 35 at least once Pelvic Inflammatory Disease: Symptoms & Tratment  Characteristics of a typical PID sufferer: young, unmarried, multiple partners, had an STI, early age at first intercourse, minority, use douches  Symptoms: acute pelvic pain, high fever, abnormal vaginal discharge Often asymptomatic  Treatment: antibiotics for 14 days Viral Infections  Once a virus enters a body, it can reproduce and the person will have it for the rest of their life Although they may not experience symptoms while the virus lies dormant, they are still infected  Common Viral STIs Herpes Human Papillomavirus Viral Hepatitis Herpes  Infection with herpes simplex virus (HSV)  The virus prefers the mouth and face (herpes simplex I) or the genitals (herpes simplex II)  The symptoms may be less severe if the virus infects a less preferred site  The virus exists in the sores, as well as from the infected skin without the sores present (viral shedding)  HSV can be spread without active symptoms  A person can reinfect themselves on another body part Herpes: Incidence & Symptoms  Incidence: one of the most common STIs in the U.S.; 1 million infected each year  Symptoms: sores that last 8-10 days, tingling/burning feeling, itching & red swollen genitals, painful urination, blisters with pus, fever, headaches, pain, itching, discharge, fatigue Over time, outbreak frequency diminishes Psychological reactions: guilt, anger, anxiety, helplessness, frustration, depression, lowered self-esteem Herpes: Diagnosis & Tratment  Diagnosis: presence of blisters, sometimes a scraping will be taken  Treatment: no cure; therapy with antiviral drugs (topical, oral, injected) to decrease outbreaks, prevent complications, & reduce viral shedding; ice pack; cooling or drying agent; L-lysine; decrease sugar & nuts Vaccines are undergoing trials Human Papillomavirus  Over 30 types of HPV  Almost all cervical cancers can be attributed to HPV and HPV can also cause genital warts  Transmitted through intercourse, oral sex, vulva-to-vulva sex, anal sex  Incidence: estimated 50% of sexually active people will get HPV Related factors: intercourse before 16, 2+ sexual partners in a year, Hispanic women Human Papillomavirus: Symptoms & Treatment  Symptoms: asymptomatic; genital warts in 10% of HPV cases (highly contagious); foulsmelling discharge; itching & pain  Diagnosis: visual inspection of warts, biopsies, Pap test  Treatment: chemical topical solutions, cryotherapy, electrosurgical interventions, laser surgery May resolve itself or need many treatments Viral Hepatitis  3 types & their transmission routes: Hepatitis A (HAV) – fecal-oral contact; vaccine-preventable Hepatitis B (HBV) – high-risk sexual behaviors Hepatitis C (HCV) – sexual behavior, drug use, unscreened blood transfusion  Incidence: HAV: 1/3 in the U.S. HBV: 1.25 million in the U.S. HCV: 3.9 million in the U.S. Viral Hepatitis: Symptoms  HAV: fatigue, abdominal pain, loss of appetite, diarrhea  HBV: asymptomatic, nausea, vomiting, headaches, jaundice, fever, fatigue, darkened urine, liver enlargement, chronic liver disease  HCV: asymptomatic, mild illness, chronic liver infection Viral Hepatitis: Diagnosis & Treatment  Diagnosis: blood test  Treatment: 3 drugs that interfere with the life cycle of the virus and induces an immune response Vaccines are available for HAV and HBV Recommended for high risk individuals HIV/AIDS Incidence Knowledge and Attitudes about AIDS Symptoms Diagnosis Treatment Prevention Families and AIDS CNN Video: Fighting AIDS in Africa Overview of HIV and AIDS  AIDS is caused by HIV  HIV is transmitted through bodily fluids (semen, vaginal fluid, blood) during vaginal & anal intercourse or by sharing needles  The virus may remain dormant, however, it is often fatal if untreated  Origin of HIV is unknown HIV and AIDS: Progression  HIV attacks T-lymphocytes (T-helper cells) in the blood, lowering the body’s ability to fight infections  Immune system releases antibodies & many white blood cells to fight the HIV infection  The lowered immune system response means many opportunistic diseases infect people with AIDS that a healthy person can easily fight Incidence of HIV/AIDS  Since 1981, 1.5 million Americans have become infected; 35-42 million worldwide  Women are the fastest growing group in the U.S. because vaginal tissue is more easily damaged during intercourse, although men drive the spread of HIV  Can be transmitted to a baby during pregnancy, labor & delivery, & breastfeeding  71% of new AIDS cases are in minorities Video: “One + One”  Discuss your response to this video.  What did you learn about HIV/AIDS? Knowledge and Attitudes about AIDS  More knowledge about AIDS in the U.S. has not been correlated with practice of safer sex or behavior changes  3 unique aspects of AIDS: Fear of transmission Social worth of those with the disease Incomprehensible magnitude of the disease  AIDS remains stigmatized in the U.S. Symptoms  Decline in T-helper cells takes 3 years if depressed, and 5+ years if not depressed  AIDS develops within 8-10 years without treatment  Early symptoms are flu like (fever, headaches, fatigue, sore throat, swollen lymph nodes)  Later symptoms: weight loss, severe diarrhea, night sweats, oral candidiasis, gingivitis, oral ulcers, fever, dizziness, confusion  Opportunistic diseases: pneumonia, toxoplasmosis, cryptococcosis, cytomegalovirus, Kaposi’s sarcoma Diagnosis  Tests typically look for antibodies that fight HIV, though some may look for HIV in blood  Antibody tests can require 2 weeks for the result  Rapid tests are less effective  False negative and false positive results are possible with all tests CNN Video: New HIV Testing Procedure Treatment  Before treatment, a viral load test and CD4+ T cell count are taken to determine how much HIV is in the system and to provide a baseline to assess the effectiveness of treatment  HAART – highly active antiretroviral therapy Blend of 3+ HIV drugs (drug cocktails) Can involve taking 25+ pills a day at different times on a strict schedule Expensive: $10,000 to $15,000 per year Side effects: fatigue, fever, rashes, nightmares, headaches, nausea, diarrhea, increased cholesterol, diabetes, lowered bone density, liver problems Prevention  Requires behavior change  Many schools now include AIDS education  HAART has been related to an increase in high risk sexual practices in homosexual men, but not among heterosexuals  If infected, inform past partners that they should be tested  Research into high risk behaviors is needed  First AIDS vaccine was found ineffective Families and AIDS  Due to the social stigma, caretakers often have no one to turn to  Adolescents that were told their parents had AIDS had more emotional distress and engaged in more high risk sexual practices Cross-Cultural Aspects of AIDS  95% of HIV cases lack access to treatment  AIDS has largely affected children  Areas throughout the world: Asia and the Pacific Europe and Central Asia Sub-Saharan Africa Latin America and the Caribbean The Middle East and North Africa Other Issues Asia and the Pacific  Over 7 million with HIV, many are young  Rising number of infections in India & China  China lacks an adequate supply of condoms  3% of Cambodia is infected  Indonesia’s rise in IV drug use adds to the HIV epidemic  Thailand has shown a decrease due to the copy of antiretroviral drugs for patients and a 100% condom use program for prostitutes Europe and Central Asia  2 million people  Large increase of HIV infections in the Russian Federation, mainly because of IV drug use Sub-Saharan Africa  Most of the people with HIV live in Africa  70% of HIV-positive people live in subSaharan Africa  Most people are not receiving HAART therapy due to costs, and they are also not being treated for opportunistic diseases  Male-female power disparity is problematic  HIV-positive men believe sex with a virgin will cure them Latin America and the Caribbean  2 million adults and children  Many countries offer free or low cost antiretroviral therapy to those with HIV/AIDS  They are able to reproduce the drugs that are not patented outside of the U.S. The Middle East and North Africa  480,000 people  Due to IV drug use, men having sex with men, prostitution, low condom usage Prevention Preventing STIs and AIDS  If sexually active, you should get tested  Have partner tested if in a sexual relationship  Carefully choose partners  Use barrier methods, such as condoms  Avoid high-risk sexual behaviors if not in a monogamous relationship  Early detection & treatment is important  Notify your sexual partners  Talking about STIs – honesty & trust