Download CASE #14

CASE #14
LEPTOSPIROSIS
PATIENT PRESENTATION
PATIENT PRESENTATION
• SIGNALMENT: 2 yr old, neutered male, Shepherd mix
• Hx: Dog goes with his owner camping and hunting twice a month.
Dog is current on DHPP vaccination, Rabies, HW & Flea prevention.
• Presenting complaint: dog is lethargic, vomiting, and seems very
thirsty.
PATIENT PRESENTATION
• PHYSICAL EXAM FINDINGS:
• ~8% dehydrated
• Temp: 103.9, HR: 100, RR:36
• Mm: icteric, CRT:2.5 sec
• DIAGNOSTIC TESTS:
• CBC: leukocytosis, thrombocytopenia
• SERUM CHEMISTRIES: increased kidney and liver enzymes
PATIENT PRESENTATION
• Vet suspects an infectious disease causing acute renal and liver failure such as
leptospirosis.
• FURTHER DIAGNOSTICS:
• URINALYSIS: low urine specific gravity
• Increase in serum titers
• Fluorescent antibody
• PCR
LEPTOSPIROSIS
• TREATMENT
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Hospitalization
IV Fluid therapy
Antibiotics: Penicillin, Doxycycine
Antibiotics
• Leptospirosis is caused by the bacteria Leptospira interrogans, a spirochete bacteria
• There are many serovars of this organism:
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Canicola
Icterohemorrhagica
Pomona
Grippotyphosa
bratislavia
LEPTOSPIROSIS
• The natural hosts of Leptospirosis are skunks, raccoons, opossums, &
pigs.
• Infection occurs through mucosal contact
(even through aerosolization) with water or soil contaminated with
urine from infected animals
LEPTOSPIROSIS
• CLIENT INFO
• Animals with Leptospirosis are contagious to humans and other animals
• Diagnosis and treatment are expensive
• Vaccination is best for prevention of clinical disease, but infected animals can
still shed the organisms in the urine.
• Current vaccines do not protect against all serovars