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Participants:林宇洲,王千一,王子文,杨哲宇 Speaker:杨哲宇 SWINE COCCIDIA 猪球虫 2008级动物医学3班 1.introduction Swine coccidium, an parasitic protozoa, parasitize in small intestine of pigs, causes the coccidiosis of pigs. The disease occurs mainly in piglets at 7 ~ 11 days age. 华山宿舍2栋413室出品 华山宿舍2栋413室出品 Morphology Toxonomy: Sporozoa, Eucoccidia, Eimeriina, Eimeriidae Eimeria and Isospora. Coccidia: 17 species, five of them are still controversial. Common species: I. suis E. debliecki, E. scabra and E. spinosa. Swine coccidium belong to Genus Eimeria and Isospora. 华山宿舍2栋413室出品 The oocysts of Isospora suis contain 2 sporoblasts . The oocysts of Eimeria contain 4 sporoblasts . 猪等孢球虫含2个孢子囊,艾美球虫则含4个孢子囊。 Isospora suis(猪等孢球虫) Eimeria艾美球虫 华山宿舍2栋413室出品 华山宿舍2栋413室出品 Life cycle The general form of swine coccidian life history is represented by the genus/sospora. This life history includes both asexual and sexual multiplication. Sexual multiplication culminates in the formation of oocysts, which are discharged with the feces. Epidemiology For clinically significant disease to occur, piglets need to be infected with relatively high numbers of oocysts Oocysts are resistant to drying and most disinfectants Most piglets are infected by oocysts carried over from previous litters Once the piglet starts scouring, the intestinal wall is damaged, and treatment will not work effectively. Symptoms Acute Scour(腹泻) tends to occur in individual pigs from approximately 6 days of age, but most of the litter scour at 8-10 days. At the start of scouring, vomiting may be seen. Scour ranges from white to pasty cream feces through to a yellowy watery scour. Piglets tend to be in poor condition, hairy and growing more slowly than other piglets within the litter Mortality rates reach 20% in acute cases Subclinical Most farms will have coccidosis at a low level affecting piglet performance Lesions The main pathological changes of piglet coccidiosis is acute enteritis, confined to the jejunum and ileum, visible serious enteritis, yellow cellulose necrotizing pseudomembrane loosely attached to the mucosal surface. 华山宿舍2栋413室出品 华山宿舍2栋413室出品 Gross lesion Microscopic lesion 华山宿舍2栋413室出品 Diagnosis According to the main symptom diarrhea and piglet age at 7 to 14 days age, and this kind of diarrhea treated invalid with antibiotics Differential diagnosis: other pathogens caused piglet diarrhea, such as E. coli, infectious virus, rotavirus, Strongyloides sterocoralis. 华山宿舍2栋413室出品 Treatment and Prevention (1)Treatment: Treat with Baycox(百球清) an oral preparation given at 4 and 10 days of age. Sulfonamides(磺胺) may also be used as treatment. 华山宿舍2栋413室出品 (2)Prevention Clean the farrowing house(分娩房) with an coccida disinfectant such as Oocide (Antec International) Reduce/cease cross-fostering(寄养) after 2-3 days of age Sows should be washed/disinfected before entering the farrowing house Use separate brushes, forks, shovels in each farrowing room Control flies Reduce draughts(賊风) and other environmental stress factors 华山宿舍2栋413室出品 欢迎观看 林宇洲,王千一,王子文,杨哲宇