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Cardiovascular Parameters Organisation of the Circulatory System • • • • Systemic and pulmonary circulations Pressure and body position alter volumes Volume alters pressure Autonomic regulation of pressure and distribution The Heart • Pericardium, Myocardium, Endocardium • Heart valves and Fibrous Skeleton • Cardiac conduction system Cardiac Cycle • Ventricular systole and diastole • Atrial filling and contraction • ECG Definitions • Systolic blood pressure: normal is 120 mm Hg • Diastolic blood pressure: normal is 80 mm Hg • Stroke volume (SV): the volume of blood ejected by contraction of the ventricle Definitions • End-systole and end diastole volumes: the volumes in the ventricle at the end of systole and the end of diastole • Heart rate (HR): the number of contractions per minute • Cardiac output (CO): CO = SV x HR • Ejection fraction: SV divided by end diastolic volume Definitions • Pulse pressure: the difference between diastolic and systolic pressures • Mean arterial pressure: the arithmetic mean of pressure in the arterial circuit ( diastolic pressure + 1/3 pulse pressure) Regulation of Cardiac Performance • • • • • • Preload Afterload Frank-Starling mechanism Cardiac contractility Inotropic effects Heart rate Blood Pressure • • • • • RAAS ADH ANP Autonomic control CNS control