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TORTORA • FUNKE • CASE Microbiology AN INTRODUCTION EIGHTH EDITION B.E Pruitt & Jane J. Stein Chapter 24, part B Microbial Diseases of the Respiratory System PowerPoint® Lecture Slide Presentation prepared by Christine L. Case Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis • Mycobacterium tuberculosis: Acid-fast rod. Transmitted from human to human • M. bovis: <1% U.S. cases, not transmitted from human to human • M. avium-intracellulare complex infects people with late stage HIV infection Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.9 Tuberculosis Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.10.1 Tuberculosis Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.10.2 Tuberculosis Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.10.3 Tuberculosis • Treatment of Tuberculosis: Prolonged treatment with multiple antibiotics • Vaccines: BCG, live, avirulent M. bovis. Not widely used in U.S. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Tuberculosis • Diagnosis: Tuberculin skin test screening • + = current or previous infection • Followed by X-ray or CT, acid-fast staining of sputum, culturing bacteria Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.11 Tuberculosis Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 14.11c Tuberculosis Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.12 Pneumomoccal Pneumonia • Streptococcus pneumoniae: Gram-positive encapsulated diplococci • Diagnosis by culturing bacteria • Penicillin is drug of choice Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 24.13 Pneumomoccal Pneumonia Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Haemophilus influenzae Pneumonia • Gram-negative coccobacillus • Alcoholism, poor nutrition, cancer, or diabetes are predisposing factors • Second-generation cephalosporins Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
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