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Maggot Debridement
Therapy
Give the “tiny surgeons” a chance!
History

Ancient Civilizations
– Maya, China, Australia

Army War Surgeons
– Napoleon, Civil War

William Baer
– John Hopkins


Ronald Sherman
House
– Burn Victim Episode
Importance to Healthcare




Diversity of wound
types
Remove necrotic
flesh
Antimicrobial
properties (MRSA)
Promote Wound
Healing
Wound Types

Any open purulent sore
– Diabetic ulcers
– Bed sores
– Burns
– Abscesses
– Basal cell carcinoma
– Vein and artery diseases
– Many more
Remove Necrotic Flesh


Mouthhooks
Excretory and
secretory products
– Enzymes


 liqification
 pH
Antibiotic Resistance




ES kill bacteria
“Gut” test
Identification of antimicrobial factors
Evolution
Healing factors




E/S stimulate EGF and IL-6
Destroy fibrin cuffs
Activate PAR system causing
vasodilation
Increase circulation thus oxygen to
wound
Maggot Biology
Application of Use




Make Pattern of
Wound
Place maggots
inside
Cover with mesh
Place gauze
bandage for
drainage
Cost and Insurance



$70/ 1000 larvae
Surgery
Antibiotics
– Vancomycin $138/day
Results

http://www.ucihs.uci.edu/com/patholo
gy/sherman/cases.htm
Results