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Breathing and Respiration State some diseases of the respiratory system Explain how these affect breathing and respiration Tuberculosis •Mycobacterium tuberculosis •Reach the alveoli •Ingested by macrophage •B cells, T cells and macrophages form granuloma •Contain bacteria that cannot be killed •Causes necrosis of lung tissue Asthsma •Narrowing and inflammation of airways •Environmental/genetic Fibrosis •Defect in gene that makes mucus and sweat glands •Large amounts of mucus in lungs •Necrosis & infection Emphysema Loss of lung surface through smoking or infection Reduced oxygen carrying capacity Diseases How does tuberculosis affect breathing and therefore respiration? How does Asthma affect breathing and therefore respiration? How does cystic fibrosis affect breathing and therefore respiration? How does Emphysema affect breathing and therefore respiration?