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0,76WXGHQW | EMT variations in cancer My project tried to capture the transformative aspect of mesenchymal epithelial transition as it relates to the environment. The basis for cell growth is very heavily reliant on the amount of oxygen or rather the lack of oxygen. This project captures that environmental constraint. The cast ltranforms in the z direction based on shape. This is representative of the cells physically changing shape based on the environmental conditions (the z axis can be seen as time, where time is increasing in the positive z direction). However, the shapes and the movement for these structures is also informed by the amount of oxygen present locally which forces them to move in and out (in the x and y direction) depending on the amount of oxygen present. 2 MIT Student | EMT in Cancer 3 Plan Axon Section 4 Logic diagram MIT Student | EMT in Cancer 5 MIT OpenCourseWare http://ocw.mit.edu 4.112 Architecture Design Fundamentals I: Nano-Machines Fall 2012 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.