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Prostate Anatomy of the prostate. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate Zonal anatomy of the prostate, a transverse view as seen on ultrasound. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate Zonal anatomy of the prostate, a sagittal view as seen on ultrasound. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate Locations of the prostate for systematic biopsy schemes. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate Lymph nodes of the prostate. The shaded area represents regional distribution of lymph nodes. The non-shaded area indicates nodes outside of regional distribution. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T1a (left) is defined as an incidental histologic finding of tumor in 5% or less of tissue resected, shown here as tissue fragments from a transurethral resection. T1b (right) is defined as an incidental histologic finding of tumor in more than 5% of tissue resected. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T2a (left) is defined as tumor that involves one-half of one lobe or less, whereas T2b (right) is defined as tumor that involves more than one-half of one lobe but not both lobes, without extracapsular extension. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T2c is defined as tumor that involves both lobes, without extraprostatic extension. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T3a is defined as a tumor with unilateral extracapsular extension. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T3a is defined as tumor with bilateral extracapsular extension. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T3b is defined as tumor that invades seminal vesicle(s). Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T4 is defined as tumor that invades adjacent structures other than seminal vesicles such as bladder, as shown here, external sphincter, rectum, levator muscles, and/or pelvic wall. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate T4 is defined as tumor that is fixed to adjacent structures. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate N1 is metastasis in regional lymph nodes, here shown unilaterally. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer Prostate N1 is metastasis in regional lymph nodes, here shown bilaterally. Compton, C.C., Byrd, D.R., et al., Editors. AJCC CancerStaging Atlas, 2nd Edition. New York: Springer, 2012. ©American Joint Committee on Cancer