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Retinoblastoma
By
Toni Dempsey
Ben Landry
Natalie Parsley
Guy Staton
Tiffany Wilcox
Ashley Willmann
What is Retinoblastoma?
Childhood cancer
 Caused by immature retinal cells in one or
both eyes
 It is most common eye cancer in children
 350 new cases in US each
year and over 5000 cases
worldwide
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Common Signs
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A white “glow” in the pupil of the eye
in dim lighting
Crossed or misaligned eyes
Poor vision
Swollen tissue around the eye
Diagnosis
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Fundoscopic examination
Computed tomography scan
MRI
Blood tests
Genetic and/or DNA testing
Treatment
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Individualized for each patient –
patients survival is primary goal
Enucleation
External Beam Radiation
Radioactive Plaques
Treatment (cont.)
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Laser Therapy
Cryotherapy
Chemoreduction/Chemotherapy
New Clinical Trial Treatments
Case Study
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Child diagnosed at 2 years of age with
Bilateral Retinoblastoma
Treated with Chemotherapy and
Radiation
Both eyes eventually had to be
enucleated
He developed unique adaptations
Implications
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Early diagnosis is critical
If left untreated cancer can spread
Over 95% of children in US survive
and lead normal lives
Follow up appointments are important
to detect possible secondary cancers