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Cancer Clinical Trials: The Way We Make Progress Against Cancer What Are Cancer Clinical Trials? • Research studies to find better ways to prevent, detect, or treat cancer • Help doctors find ways to improve cancer care 2 Why Are Cancer Clinical Trials Important? • Most of the best cancer treatments we have today are based on what we learned from clinical trials • People with cancer are living longer because of clinical trials 3 Do Many People Take Part in Cancer Clinical Trials? • Few people take part • The more people who take part, the faster we will find better ways to treat and prevent cancer 4 What Are the Different Types of Clinical Trials? • • • • Treatment Prevention Diagnostic Screening/early detection • Quality of life 5 Treatment Trials • What new treatments can help people who have cancer? • What is the most effective treatment for people who have cancer? 6 Treatment Trials • Many treatment trials compare two or more different approaches to treating cancer • Participants will take either: – The best accepted cancer treatment – A new treatment 7 Prevention Trials What approaches can prevent a specific type of cancer from developing in people who don’t have cancer? 8 Prevention Trials Two kinds, that ask participants to either: 1. Do something 2. Take something 9 Protecting Patients’ Safety Informed Consent Before agreeing to take part, patients have the right to understand all that is involved in a clinical trial: • Procedures and treatments • Tests • Possible risks and benefits 10 Protecting Patients’ Safety Institutional Review Boards • Committee made up of experts 11 Benefits of Taking Part Possible benefits: • Patients will receive, at a minimum, the best standard treatment • If the new approach is proven to work, patients may be among the first to benefit • Patients have a chance to help others and improve cancer care 12 Risks of Taking Part Possible risks: • Unknown side effects or other risks • New treatment may not help every participant • Costs 13 Where to Find Clinical Trial Information • Your doctor or nurse • National Cancer Institute – www.cancer.gov • Cancer Information Service – 1-800-4-CANCER – TTY- 1-800-332-8615 14