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You have a population of mice that you are breeding in the lab. There are 132 mice in the population. 48 of them are white, a recessive trait. What is the frequency of the recessive allele? 48/132 = .36 √.36 = .6 You have a population of mice that you are breeding in the lab. There are 132 mice in the population. 48 of them are white, a recessive trait. What is the frequency of the homozygous dominant genotype? q = .6 p = 1-.6 = .4 P2 = .16 You have a population of mice that you are breeding in the lab. There are 132 mice in the population. 48 of them are white, a recessive trait. What is the frequency of the heterozygous genotype? 2pq = 2 x .4 x .6 2pq = .48 After graduation, you and 24 friends build a raft, sail to a deserted island, and start a new population, totally isolated from the world. One of your friends carries (is heterozygous for) the recessive cf allele, which in homozygotes causes cystic fibrosis. Assuming that the frequency of this allele does not change as the population grows, what will be the instance of cystic fibrosis on your island? 25 people. One person carries cf. 49 alleles are dominant, 1 allele is recessive. q = 1/50 = .02 p = 49/50 = .98 q2 = .02 x .02 = .0004 (or .04%) If 9% of an African population is born with a severe form of sickle-cell anemia (ss), what percentage of the population will be more resistant to malaria because they are heterozygous(Ss) for the sickle-cell gene? q2 = .09 q = .3 p = .7 2pq = 2 x .7 x .3 = .42 Wing coloration of the scarlet tiger moth is controlled by a single gene in an incomplete dominance pattern. Data was collected for 1612 individuals. White-spotted (AA) =1469 Intermediate (Aa) = 138 Little spotting (aa) =5 Calculate the following frequencies for this population: A= a= AA = Aa = aa = Wing coloration of the scarlet tiger moth is controlled by a single gene in an incomplete dominance pattern. Data was collected for 1612 individuals. White-spotted (AA) =1469 Intermediate (Aa) = 138 Little spotting (aa) =5 Calculate the following frequencies for this population: A = 3076/3224 = .954 a = 148/3224 = .046 AA = 1469/1612 = .911 Aa = 138/1612 = .085 aa = 5/1612 =.003 57 high school students at Coral Shores were surveyed to see if they could taste the chemical PTC. 14 of them could not. What are the allele frequencies in the population? q2 = 14/57 = .25 q = .5 p = .5 57 high school students at Coral Shores were surveyed to see if they could taste the chemical PTC. 14 of them could not. What are the genotype frequencies in the population? q2 = .25 2pq = .5 p2 = .25 57 high school students at Coral Shores were surveyed to see if they could taste the chemical PTC. 14 of them could not. If the surveyed students are representative of the population, how many of the 743 students at the school would you expect will be able to taste PTC? If the surveyed students are representative of the population, how many of the 743 students at the school would you expect will be able to taste PTC? .75 x 743 = 557 If a specific, recessive allele is selected against, what would you expect to see in the allele frequencies over several generations? q would decrease p would increase If a specific, recessive allele is selected against, would you expect that allele to be lost from the population? No. Carriers would pass the allele to subsequent generations. If a specific, dominant allele is selected against, what would you expect to see in the allele frequencies over several generations? p would decrease q would increase If a specific, dominant allele is selected against, would you expect that allele to be lost from the population? Yes. There are no carriers. The allele may be eliminated over time. If there is an advantage to being heterozygous, what effect would this have on the allele frequencies of the population? q would be higher than if there was no benefit to being heterozygous How would immigration and emigration effect the allele frequencies of an established population? It would change the frequencies of the alleles in the gene pool. Equilibrium would eventually be reestablished, but the frequencies would probably be different. How does selective mating effect the allele frequencies within a population? The frequency of the selected FOR allele would increase. The frequency of the selected AGAINST allele would decrease. If a population is small and isolated, what might you expect to see in the allele frequencies? Random chance may cause aWhat shiftisinthis frequencies. process called? Either allele could become more prominent. Genetic Drift What is natural selection? What is artificial selection? What animals are currently undergoing artificial selection? What are some of the sideeffects of artificial selection?