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Introduction to Oral Cancer
Gene Database
．資訊三 朱民晃 B92902025
．資訊三 陳皓遠 B92902062
The Tumor Gene Family
Databases
Introduction(1/2)
• http://www.tumor-gene.org/
• The Tumor Gene Family of Databases contains
information about genes which are targets for
cancer-causing mutations; proto-oncogenes and
tumor supressor genes.
• These databases are designed to for
biomedical researchers who work with
tumor genes.
Introduction(2/2)
• Tumor Gene Database
• Breast Cancer Gene Database
• Oral Cancer Gene Database
Oral Cancer Gene Database
• What information dose the database
contain?
• This database contains information about
genes which are targets for cancercausing mutations in oral cancers.
• List of Oral Cancer Genes
• A member of the Tumor Gene Database
family
• http://www.tumor-gene.org/Oral/oral.html
Get the list of Oral Cancer Genes
(1/2)
Click here to get information
of the Oral cancer list
Get the list of Oral Cancer Genes
(2/2)
• List of Oral Cancer Genes
How to search the database (1/4)
Key in a Gene Name or
a word in a fact you
want to search
How to search the database (2/4)
Click the “Search” button to search
How to search the database (3/4)
Get 1 match of the gene “BAX”
Click the hyperlink of “BAX”
How to search the database (4/4)
OMIM ID Number of NCBI
OMIM ID Number
What can we get ? (1/2)
• Cell Type Distribution
• Clinical
• Complementation
• Function
• Gene Frequency (Tumors)
• Protein Binding
• Regulation
What can we get ? (2/2)
Link to Citation of NCBI
Flag
Flags
Primary Fact from a Full Paper
Primary Fact from an Abstract
Secondary Fact from a Full Paper
Secondary Fact from an Abstract
Primary Fact from a Review
Secondary Fact from a Review
Unknown
Link to GeneCards (1/2)
Click here to link to
GeneCards website
Link to GeneCards (2/2)
NCBI – OMIM (1/4)
Remember to choose “OMIM”
*600040 , the OMIM ID Number
NCBI – OMIM (2/4)
Click here; go to the OMIM homepage.
Click “FAQ” to get details about OMIM
NCBI – OMIM (3/4)
What do the symbols preceding
a MIM number represent?
NCBI – OMIM (4/4)
Ex:
An asterisk (*) before an entry number
indicates a gene of known sequence.
Conclusion
• We can search the information about oral
gene in the database.
• We can get the OMIM ID about the gene
in the NCBI database.
• We can get the list of genes in the oral
database.
• We can link to GeneCards website.
Thanks for your
attention.