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Chapter 3: Genetics Mendel’s Peas Discreet Units of Inheritance (genes) Genes Inherited Independently (Independent Assortment) Cells Cell Cytoplasm Nucleus Chromosomes Diploid Organisms Have Chromosomes Organized in Homologous Pairs Humans have 46 Chromosomes (23 Homologous Pairs) Cell Division Mitosis Making Somatic Cells Diploid Daughter Cells Meiosis Making Sex Cells Haploid Gametes (eggs & sperm) Genes: DNA Alleles (different varieties of genes) Homozygous Heterozygous Terms • Genotype = the particular genes or alleles that an individual has • Phenotype = the observable trait of a individual’s genotype • Dominant = individuals with only one copy of the allele have the same phenotype • Recessive = individuals need two copies of the allele, no effect in the heterozygotes Mendel’s Peas Again F0 to F1 Parent Generation (F0) True Breeding for Seed Color Homozygous Genotypes = AA & aa Phenotype = Yellow & Green Meiosis Haploid Sex Cells Sex Daughter Generation (F1) Heterozygous Genotype = Aa Phenotype = Yellow Mendel’s Peas Again F1 to F2 Genotype = Aa Phenotype = Yellow F1 Generation Meiosis Sex F2 Generation Punnett Square A a A AA Aa a Aa aa Genotype = 1:2:1 Phenotype = 3:1 Punnett Square A a A AA Aa A AA Aa Genotype = 1:1 Phenotype = 1 Punnett Square a a A Aa Aa A Aa Aa Genotype = 1 Phenotype = 1 Punnett Square a a A Aa Aa a aa aa Genotype = 1:1 Phenotype = 1:1 Punnett Square 2 Genes/Traits ab ab A B Aa Bb Aa Bb A B Aa Bb Aa Bb Genotype = 1:1 Phenotype = 1:1 Punnett Square 2 Genes/Traits AB Ab AB Ab aB ab aB ab AA BB AA Bb Aa BB Aa Bb AA Bb AA bb Aa Bb Aa bb Aa BB Aa Bb aa BB aa Bb Aa Bb Aa bb aa Bb aa bb Genotype = All Different Phenotype = 9:3:3:1 Crossover DNA = Deoxyribonucleic Acid Bases: Backbone Is made of Phosphates & Sugars Adenine Thymine Guanine Cytosine A G T C T C A G Paired Making an Exact Copy Making a Protein DNA A T T C G A C C G U A A G C U G G C Amino Acid 1 mRNA Amino Acid 2 tRNA C G A U A A G C U G G C Cytoplasm mRNA