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ABO System • H gene • Se gene • AB genes • • • • L – Fucose N –acetyl galactosamine Galactose N-acetylglucosamine ABO Blood Group Antigens A NAG Gal Precursor oligosaccharide NAcGA Fuc H NAG Gal NAG Gal A antigen Fuc B antigen H antigen NAcGA (N-acetylgalactoseamine) Gal (galactose) NAG B Gal Fuc Gal ABO Blood Group Reactivity blood group to (phenotype) A B AB O O genotypes antigens antibodies AA, AO BB, BO AB OO hh ABO in serum A anti-B B anti-A A and B none H anti-A/B none anti A,B,H روشهای انجام گروه خون • Direct method (cell type) Unknown RBC + anti A ,anti B • Indirect method (back type) A cell , B cell + unknown serum Rh system • D ,C,c,E,e genes DCe / c E DCE / ce Ce / CE Dce / DCE Cell type RBC + anti D