Survey
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
Download Developmental Genetics
Document related concepts
no text concepts found
Transcript
Developmental Genetics Three Stages of Development • division • morphogenesis • differentiation What leads to changes? • Differential gene expression. • Caused by... Sequential Regulation • Gene Expression is sequentially regulated • Cells become determined before they differentiate Plant and animal devo • Plants have totipotent stem cells (meristems) throughout life • Animals have totipotent stem cells for short part of life • Animal cells move in development Of course we have videos • Human Development • Different types of potential cells • Embryonic stem cell lines • Nuclear transfer: cloning Cloning • Reproductive cloning • Many problems • Defects • Too many methyl groups Stem Cells • Adult stem cells • Bone marrow • Brain • Skin • Hair • Eyes • Dental pulp • Embryonic stem cells are pluripotent • Therapeutic cloning • New induced pluripotent stem cells from adult cells. Pattern Formation in Animals • Establishes major axes: • Anterior posterior • Right and left sides • Video Homeotic Genes • Homeotic genes contain homeobox sequences (180 nucleotides long) regulate body part formation • Homeobox codes for homeodomain (60 aa long) • Homeodomains are almost identical in animal kingdom • A video…of course
Related documents