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Transcript 
(black)
1 gene with 2 alleles
we’ve seen 4 cases:
complete dom/rec
incomplete dominance
codominant
recessive lethal (dom. marker)
1 AA :
dom
dom
dom1
dead
2 Aa
:
1 aa
dom
rec
blend dom-rec
rec
dom1+ dom2
dom2
dom
rec
IC. Genes with multiple alleles
1 Gene with 3 alleles
IA & IB are co-dominant; i is recessive
IC. Genes with multiple alleles
Hierarchy of dominance:
C > cch > ch > c
IC. Genes with multiple alleles
chinchilla
cch
IC. Genes with multiple alleles
chinchilla
cch
IC. Genes with multiple alleles
chinchilla
cch
himalayan
ch
IC. Genes with multiple alleles
Hierarchy of dominance:
C > cch > ch > c
IC. Genes with multiple alleles
IC. Genes with multiple alleles
A short list of the 1587 known mutant alleles of the
Drosophila melanogaster eye color gene w (white)
ID. Two genes, interacting
Back to
2 genes
TIME
ID. Two genes, interacting
A/A ; B/B
a/a ; b/b
A/a ; B/b self-cross
A/_ ; B/_
A/_ ; b/b
a/a ; B/_
a/a ; b/b
ww
m+ & m
Coat color:
Genes
A, B, C, D, E, S
A
AY
B
cc
C
C
C
D
E
E
II. Mention epistasis versus suppression
S
III.
Genotype -> Phenotype
. . . but with interactions of unknown other genes, environment, + . . .
Lack of
Penetrance
Variable
Expressivity
Lack of
Penetrance
.4
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