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Figure removed due to copyright considerations. See Stix, Gary. “Trends in Micromechanics: Micron Machinations.” Scientific American (November 1992): 107-117. Figure removed due to copyright considerations. See Lodish, H., et. al. Molecular Cell Biology. 4th ed. New York: W. H. Freeman & Co., 1999, 284. [glycocalyx] IGF-1 Analog T G N-terminus Q A +R +R P I A D T E L 6 C D 47 C C C 52 48 70 L + R S Q +K N F V C C F L 61 Y L P +K E A T +K P E D G A M V G Y L S A L S +R F +R G S C-terminus V missing S A G Y P F D +R G 18 D = Asp E = Glu COOH K = Lys R = Arg NH+3 ( +) COO + H+ ( ) NH2 + H+ pK ~ 4 pK ~ 10.5 -12.5 Figure by MIT OCW. (9) (-) (9) (+) Figure removed due to copyright considerations. See Fig. 3-3 in Lodish, H., et. al. "Hydrophilic and Hydrophobic Amino Acid Structures." Molecular Cell Biology. 4th ed. New York: W. H. Freeman & Co., 1999. MEMs with Micro-Gel Electrophoresis Figures removed due to copyright considerations. See Burns, M. A., et. al. "An Integrated Nanoliter DNA Analysis Device." Science 282, no. 484 (Oct. 1998).