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a Structures
Coiled-coil structureknob in hole
Source: Introduction to Protein Structure by Branden & Tooze
Coiled-coil structure. Two a helices are interwined
and gradually coil around each other.
Source: Introduction to Protein Structure by Branden & Tooze
Repetitive pattern of amino acids in a coiledcoil a helix.
Source: Introduction to Protein Structure by Branden & Tooze
Packing of hydrophobic side chains between
the two a helices in a coiled-coil structure.
Source: Introduction to Protein Structure by Branden & Tooze
Salt bridge in a coiled-coil a helix.
Source: Introduction to Protein Structure by Branden & Tooze
“Knobs in holes” in a coiled-coil a helix.
Source: Introduction to Protein Structure by Branden & Tooze
Dimeric Rop molecule“knobs in holes” + “ridges in grooves”
Source: Introduction to Protein Structure by Branden & Tooze
Globin Domain
Source: Introduction to Protein Structure by Branden & Tooze
Ridge on groove
Source: Introduction to Protein Structure by Branden & Tooze
ridges & groovessurface of side chains of a helix
Source: Introduction to Protein Structure by Branden & Tooze
Helix packing by “ridges in grooves”
Source: Introduction to Protein Structure by Branden & Tooze
Sickle-cell hemoglobin
Source: Introduction to Protein Structure by Branden & Tooze
Hemoglobin molecule
Source: Introduction to Protein Structure by Branden & Tooze
Sickle-cell hemoglobin molecules polymerization.
Source: Introduction to Protein Structure by Branden & Tooze
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