Download AA01 structure

L-Form Amino Acid Structure
Carboxylic group
Amino group
+
H3 N
R group
COO
a
-
H
H = Glycine
CH3 = Alanine
Juang RH (2004) BCbasics
Mirror Images of Amino Acid
a
Mirror
image
a
Same chemical properties
Stereo isomers
Juang RH (2004) BCbasics
Northwest line Chung-San line
-C-C-C-N-C-N
=
Aromatic
Trp W -C-
N+
Basic Arg R
This is NOT a metabolic pathway
N
-C-
-OH
Tyr Y
Lys K
+
-C-C-CONH2
Asn N
Gln Q Amide
Asp D
Glu E Acidic
-C-COOH
-C-C-COOH
-C-
-C-C C
N N+
His H
Central line Gly G
Phe F
Ala A
A
Val V
Ile I
-CH3
C C
-C
C
-C-C-C
-H
-C-OH
Ser S
Cys C
-C-SH
Circular line
South line
Non-polar
Polar
Nan-Kan line
-C-CONH2
-C-C
OH
Thr T
Met M
Hydroxy
Sulfur
-C-C-S-C
Aliphatic
Leu L
C
-C-C-C
C
C
C
HN C-COOH
a
Pro P
Imino,
Circular
Juang RH (2004) BCbasics
-C-C-C-C-NH3
Amino Acid Subway Map
Classification of Amino Acids by Polarity
NONPOLAR
POLAR
Acidic
Neutral
Basic
Asp
Asn Ser
Arg
Cys
Tyr
His
Gln
Thr
Lys
Glu
Gly
Ala Ile
Phe Trp
Val Leu Met Pro
Polar or non-polar, it is the bases of the amino acid properties.
Juang RH (2003) Biochemistry
Formation of Peptide Bonds by Dehydration
Amino acids are connected head to tail
NH2
1
COOH
NH2
2
COOH
Dehydration
Carbodiimide
-H2O
O
NH2
1
C N
2
COOH
H
Juang RH (2004) BCbasics
Peptide Bond Is Rigid and Planar
C
H
C
O
N
C
Juang RH (2004) BCbasics