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Biochemistry Matter & Elements •All matter made of elements (atoms) •All atoms have structure •Protons/electrons/neutrons? Charge? Mass? (Chart) •# of protons in nucleus determines atom’s identity •Ions atoms that gain or lose electrons Hemoglobin Atom Atomic Structure Protons carry a +1 charge, mass of 1 AMU Neutrons carry a 0 charge; mass of 1AMU Electrons carry a –1charge; mass of 0 AMU Nucleus consists of protons and neutrons; central part of the atom Electrons move around the nucleus Why Atoms Form Bonds •2 or more elements = compound •1st 20 elements have up to 3 energy levels/ 2 electrons on 1st level, up to 8 on 2nd level, and 8 on the 3rd level •Most elements want to have 8 electrons in outer shell •Atoms will share or steal to get 8 electrons in outer shell •Sharing electrons covalent bonds •Stealing electrons ionic bonds Covalent Bond In Action Ionic Bond In Action NaCl- Ionic Bond CH4- Covalent Bond Chemical Changes, Chemical Symbols, & Formulas Chemical Symbols- look at P.T. Chemical Formulas group of symbols together Exp. H2O, CO2, 5H2O Acids and Bases Pure water has equal amounts of H+ and OHIf equal number of H+ and OH-, solution is neutral pH Scale Scale measures amount of H+ ions in solutions pH = 7-neutral pH< 7 –acidic pH > 7--basic Polarity of Water Structure of water is VERY unique H2O •Oxygen has 8 protons & 8 electrons •Opposites attract, and electrons are pulled in close to the nucleus •Hydrogen has 1 proton & 1 electrons •Not held together very closely Water’s Structure •In H2O, Oxygen slightly pulls the electrons away from the 2 Hydrogen molecules •Oxygen becomes partially negative •Hydrogen becomes partially positive •Water is a POLAR molecules (slightly charged) •Polarity makes water stick together Polarity of Water Polarity of Water Physical Properties of water •Ice floats •Water absorbs and retains heat •Water molecules stick to each other •Water molecules stick to other polar substances Ice floats: •When water freezes, hydrogen bonds lock water molecules into a structure that has empty spaces, making it less dense than liquid water Water absorbs and retains heat Because of hydrogen bonds, water can absorb large amounts of energy Absorbs lot of heat before it boils Helps keep cells at an even temperature despite changes in the environment – homeostasis again!! Allows large bodies of water to maintain a relatively constant temperature. Energy In living organisms, energy is stored as chemical, mechanical, and thermal energy Types of Energy Potential Energy – stored energy; energy of position Kinetic Energy- Energy of motion Law of Conservation of Energy- energy is not created or destroyed in a chemical reaction (1st Law of Thermodynamics) Energy & Chemical Reactions Reactants = substances that begin a chemical reaction Products = substances that are made from a chemical reaction A + B AB Reactants Products Different Types of Reactions Exergonic Reaction = releases energy Endergonic Reaction = absorbs energy Oxidation Reactions = reactant loses electrons Reduction Reaction = reactant gains electrons Organic Examples Carbohydrates •provide energy to cells •help build cell structures •monosaccharides= 1 sugar unit •disaacharides = 2 connected sugar units •polysaccharides = more than 2 connected sugar units Glucose- The Ultimate Carbohydrate Lipids Fats (triglycerides) Used for energy Long chain molecules Triglyceride = 3 FA’s + glycerol Saturated= not easily broken down (all single bonds) Unsaturated= easily broken down (double bonds) The Phospholipid Bilayer Proteins THE structural material of the body! 1. Hormones 2. Receptors 3. Enzymes Made from Amino Acids (connected via peptide bonds) Collagen Hemoglobin Levels of organization: Keratin-The Protein of Hair and Fingernails Hemoglobin = Transport Protein Nucleic Acids •Make our genes •Instruct body which proteins to make •Made from nucleotides •DNA + RNA