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Components of Blood • Whole blood – RBCs – WBCs – Platelets: cell fragments that aid in clotting • Plasma – 90% water (allows materials to dissolve) – Amino acids, glucose, hormones, vitamins, salts, waste – Concentrations allows diffusion in/out of blood stream Red Blood Cells • • • • Job: Transport O2 to cells Produced from stem cells in bone marrow O2 binds to hemoglobin proteins Dead cells filtered by liver & spleen Sickle Cell Normal White Blood Cells • Remove foreign invaders & dead cells • Able to move through body tissue Platelets • Form clots when bleeding • Proteins form a web to trap cells & platelets ABO Blood Groups • Proteins on blood cells determine blood type • Antigen (markers) – proteins on cell’s surface that identify cells as foreign or natural • Antibodies: – proteins from B cells to attack invaders – Float freely in plasma Group A blood • A antigens on the surface of your RBCs • B antibodies in your blood plasma Group B blood • B antigens on the surface of your RBCs • A antibodies in your blood plasma Group AB blood • Both A and B antigens on the surface of your RBCs • Neither A or B antibodies in your blood plasma Group O blood • Neither A or B antigens on the surface of your RBCs • Both A and B antibodies in your blood plasma If you have type A blood, can you receive: Type B blood from a donor? Type AB blood from a donor? Type O blood from a donor? If you have type B blood, can you receive: Type A blood from a donor? Type AB blood from a donor? Type O blood from a donor? If you have type AB blood, can you receive: Type A blood from a donor? Type B blood from a donor? Type O blood from a donor? If you have type O blood, can you receive: Type A blood from a donor? Type B blood from a donor? Type AB blood from a donor? Rh Factors • If Rh+ – Cells contain the Rh antigen – Can receive Rh+ or Rh- blood • If Rh– Cells lack the Rh antigen – Plasma contains Rh antibody – Only receive Rhblood Francis was just in a bad accident and lost a lot of blood. He is blood type B+. Can you help save him? Blood type B+ Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh Francis has B+ blood type because of the B and Rh antigens. If he is given B+ blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive B+ blood? Yes. Vein Francis has B+ blood type because of the B and Rh antigens. If he is given B- blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive B- blood? Yes. Vein Francis has B+ blood type because of the B and Rh antigens. If he is given A+ blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive A+ blood? Agglutination: No. clumping of the blood Vein Francis has B+ blood type because of the B and Rh antigens. If he is given A- blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive A- blood? Agglutination: No. clumping of the blood Vein Francis has B+ blood type because of the B and Rh antigens. If he is given AB+ blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive AB+ blood? Agglutination: No. clumping of the blood Vein Francis has B+ blood type because of the B and Rh antigens. If he is given AB- blood in a transfusion… Will his antibodies attack this blood? Yes. His A antibodies will attack the A antigens. Can he receive AB- blood? Agglutination: No. clumping of the blood Vein Francis has B+ blood type because of the B and Rh antigens. If he is given O+ blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive O+ blood? Yes. Vein Francis has B+ blood type because of the B and Rh antigens. If he is given O- blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive O- blood? Yes. Vein Sebastian was just involved in an accident at work and lost a lot of blood. He is blood type A-. Can you help save him? Blood type AAntigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh Sebastian has A- blood type because of the A antigen. If he is given A- blood in a transfusion… Will his antibodies attack this blood? No. His B and Rh antibodies only attack B and Rh antigens. Can he receive A- blood? Yes. Vein Sebastian has A- blood type because of the A antigen. If he is given A+ blood in a transfusion… Will his antibodies attack this blood? Yes. His Rh antibodies will attack the donated Rh antigens. Can he receive A+ blood? No. Vein Agglutination: clumping of the blood Sebastian has A- blood type because of the A antigen. If he is given B- blood in a transfusion… Will his antibodies attack this blood? Yes. His B antibodies will attack the donated B antigens. Can he receive B- blood? No. Vein Agglutination: clumping of the blood Sebastian has A- blood type because of the A antigen. If he is given B+ blood in a transfusion… Will his antibodies attack this blood? Yes. Both his B and Rh antibodies will attack the donated B an Rh antigens. Can he receive B+ blood? No. Vein Agglutination: clumping of the blood Sebastian has A- blood type because of the A antigen. If he is given AB- blood in a transfusion… Will his antibodies attack this blood? Yes. His B antibodies will attack the donated B antigens. Can he receive AB- blood? No. Vein Agglutination: clumping of the blood Sebastian has A- blood type because of the A antigen. If he is given AB+ blood in a transfusion… Will his antibodies attack this blood? Yes. Both his B and Rh antibodies will attack the donated B and Rh antigens. Can he receive AB+ blood? No. Vein Agglutination: clumping of the blood Sebastian has A- blood type because of the A antigen. If he is given O+ blood in a transfusion… Will his antibodies attack this blood? Yes. His Rh antibodies will attack the donated Rh antigens. Can he receive O+ blood? No. Vein Agglutination: clumping of the blood Sebastian has A- blood type because of the A antigen. If he is given O- blood in a transfusion… Will his antibodies attack this blood? No. His A antibodies only attack A antigens. Can he receive O- blood? Yes. Vein Blood type AB+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh Blood type O+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh Blood type ABAntigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh Blood type B+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh Blood type OAntigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh 1) Can this work? • Acceptor • Donor O- AB- 2) Can this work? • Acceptor • Donor A+ A- 3) Can this work? • Acceptor • Donor AB- B- Kobe Kuiz 1) 2) 3) 4) 5) 6) What are the components found inside blood? What are the ingredients of plasma? What is the purpose/function of RBCs? Which part of blood stop bleeding when cut? What do antibodies bind with? If a person has type AB-, which antigens do they possess? Which antibodies? 7) If a person has type O+, which antigens do they possess? Which antibodies? 8) If a person is type A-, list all the blood types this person can receive in a transfusion. 9) If a person is type O-, list all the blood types this person can receive in a transfusion.