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INTEGUMENTARY SYSTEM Skin SKIN • Formation of Epidermis – – – – – – – – – Embryonic Ectoderm Basale Cells Stematic Cells Proliferative Cells Epidermal Growth Hormone Single Layer Cuboidal Epithelial Layer Mitosis Increase In Number Proliferative Cells SKIN • Formation of Epidermis – Differentiation – Keratinocytes – Formation of Stratum Spinosum – Keritinization – Formation of Stratum Granulosum – Formation of Stratum Lucidium – Eleidin SKIN • Formation of Epidermis – Formation of Corneum – Dead Keratinized Cells SKIN • Melaninization – Melaninocytes – Amino Acid Uptake – Protein Synthesis – UVL Exposure – Tyrosine – Tyrosinase – Rough Endoplasmic Reticuli – MSH SKIN • Melaninization – MSH – Protein Synthesis – Tyrosine – Tyrosinase – RER – Melanin – Melanin vacuoles SKIN • Dispersal of Melanin – MSH – UVL – Diffusion Dispersal – Phagocytosis – Umbrella Over DNA – Protection Of Nuclei – Stratum Basale – Stratum Spinosum SKIN • Epidermal Langerhan Cells – WBC’s – Monocytes – Wandering Macrophages – Lymphocytes – T Lymphocytes – Wandering Lymphocytes – Protection SKIN • Epidermal Langerhan Cells – Phagocytosis – Antigenic Presenting Cells – Lymphocytes – Lymphatic Response – Protection – Host Cell for HIV SKIN • Sensory Neurons – – – – – – – – – Tactile Neurons Merkel Cells Axonic Propagation Axonic Action Potential Axonic Depolarization Na+1 Influx +30mV Thalamus Post Central Gyrus
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