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Transcript 
Figure 3.14A–D Protein structure (layer 1)
Levels of Protein Structure
Leu Met
Pro
Gly Glu
Gly
Thr
Cys
Ser Lys
Val
Lys
Val
Asn Val
Ile
Ala
Leu Asp Ala Val Arg Gly Ser Pro
Amino acids
Copyright © 2005 Pearson Education, Inc. Publishing as Benjamin Cummings
Ala
Val
His Val
Phe
Arg
Figure 3.14A–D Protein structure (layer 2)
Levels of Protein Structure
Leu Met
Pro
Cys
Gly Glu
Gly
Val
Ala
Ile
Lys
Ser Lys
Thr
Asn Val
Val
Val
Ala
His Val
Arg
Phe
Leu Asp Ala Val Arg Gly Ser Pro
Amino acids
Hydrogen
bond
O H
C
N
C
C
C
H
N
N
O
C
N H
C
O
H
O
C
C
O
H
O
C
C
N
H
N H
O
C
O
N
C
N
C
H
O
CN
R
H
H
CC
O
H
C
C
N
C
CN
CC
H
C
H
C
C
N
H O
N
C
N H
C
O
C
O
H
H
O
R
C
C
H
N CC
N
H
O
O
H
N C C N
O
H
C C
N
O
H
O
C
C
N
H
C
O
C N
O
C N
O
H
C
C
C
C
H
N C C
N
H
O
O
C
C
N
H
Alpha helix
Copyright © 2005 Pearson Education, Inc. Publishing as Benjamin Cummings
Pleated sheet
C
H
C N
O
C
Figure 3.14A–D Protein structure (layer 3)
Levels of Protein Structure
Leu Met
Pro
Cys
Gly Glu
Gly
Val
Ala
Ile
Lys
Ser Lys
Thr
Asn Val
Val
Val
Ala
His Val
Arg
Phe
Leu Asp Ala Val Arg Gly Ser Pro
Amino acids
Hydrogen
bond
O H
C
N
C
C
C
H
N
N
O
C
N H
C
O
H
O
C
C
O
H
O
C
C
N
H
N H
O
C
O
N
C
N
C
H
O
CN
R
H
H
CC
O
H
C
C
N
C
CN
CC
H
C
H
C
C
N
H O
N
C
N H
C
O
C
O
H
H
O
R
C
C
H
N CC
N
H
O
O
H
N C C N
O
H
C C
N
O
H
O
C
C
N
H
C
O
C N
O
C N
O
H
C
C
C
C
H
N C C
N
H
O
O
C
C
N
H
Alpha helix
Polypeptide
(single subunit
of transthyretin)
Copyright © 2005 Pearson Education, Inc. Publishing as Benjamin Cummings
Pleated sheet
C
H
C N
O
C
Figure 3.14A–D Protein structure (layer 4)
Levels of Protein Structure
Leu Met
Pro
Cys
Gly Glu
Gly
Val
Ala
Ile
Lys
Ser Lys
Thr
Asn Val
Val
Val
Ala
His Val
Arg
Phe
Leu Asp Ala Val Arg Gly Ser Pro
Amino acids
Hydrogen
bond
O H
C
N
C
C
C
H
N
N
O
C
N H
C
O
H
O
C
C
O
H
O
C
C
N
H
N H
O
C
O
N
C
N
C
H
O
CN
R
H
H
CC
O
N
C
CN
CC
H
C
H
C
C
N
H O
N
C
N H
C
O
C
O
H
H
O
R
C
C
H
C
C
H
N CC
N
H
O
O
H
N C C N
O
H
C C
N
O
H
O
C
C
N
H
C
O
C N
O
C N
O
H
C
C
C
C
H
N C C
N
H
O
O
C
C
N
H
Alpha helix
Polypeptide
(single subunit
of transthyretin)
Transthyretin, with
four identical
polypeptide subunits
Copyright © 2005 Pearson Education, Inc. Publishing as Benjamin Cummings
Pleated sheet
C
H
C N
O
C
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