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What Milk? Jo Caines Paediatric Specialist Dietitian Breastfeeding 1st choice - continuation of breastfeeding ? Mother may require exclusion diet if child has severe eczema or gastrointestinal symptoms Most evidence with maternal exclusion diets is for cow’s milk and egg ? Calcium supplementation for mother if excluding cow’s milk Degree of Hydrolysis Extensively Hydrolysed Casein Formula (EHC-F) Nutramigen 1 (£8.20/400g) Well tolerated in younger infants Unpalatable Nutramigen 2 > 6 months Tastes better and has increased calcium Pregestimil (£8.91/400g) Similar formula containing increased level of medium chain triglycerides useful in fat malabsorption Extensively Hydrolysed Whey Formula Pepti (£17.10/900g) More palatable than extensively hydrolysed casein formulas Contains lactose Larger peptides - ? Less well tolerated Useful in children who refuse EHC-F Pepti Junior (£9.42/400g) Contains MCT’s Does not contain lactose More expensive than Pepti Amino Acid Formulas Neocate LCP and Nutramigen AA Suitable for children with: - multiple food allergies - children with food allergy and GI symptoms/faltering growth - failure of extensively hydrolysed formula Expensive (Neocate £22.02/400g, NutramigenAA £21.22/400g) Unpalatable but very effective Amino Acid Formulas Neocate Advance (£35.50/15x50g) >1 year 1kcal ml Need large volumes to be nutritionally complete but can be used as a sole source of nutrition Neocate Active (£49.12/14x63g) > 1year 1kcal/ml Increased iron and calcium to meet requirements in 600mls Designed as a supplement to diet Soya Formulas Safety concerns regarding effect of phytoestrogens (COT 2003) Cross reactivity with cow’s milk protein - Non IgE Up to 60% - IgE 17-47% More palatable SMA Wysoy(£7.58/860g) / Cow & Gate Infasoy (£7.44/900g) / Heinz Soya Nurture Formula BDA Paediatric Group (2004) - Avoid < 6/12 as a precautionary measure - Vegans, Galactosaemia, CMPA refusing eHF Partially Hydrolysed Formulas Not suitable for cow’s milk protein allergy treatment More peptides with high molecular weight Antigen content reduced to avoid primary sensitisation Example: NAN HA (£4.29/400g)