Download Drug Control Centre 2008 Research Papers- Peer-reviewed Journals

Drug Control Centre
Research Papers- Peer-reviewed Journals
2008
Walker, C.J., Cowan, D.A., James, V.H.T., Lau, J.C.Y., Kicman, A.T.
Doping in sport-2. Quantification of the impurity 19-norandrostenedione in pharmaceutical
preparations of norethisterone
(2008) Steroids, . Article in Press.
Parkin, M.C., Turfus, S.C., Smith, N.W., Halket, J.M., Braithwaite, R.A., Elliott, S.P.,
Osselton, M.D., Cowan, D.A., Kicman, A.T.
Detection of ketamine and its metabolites in urine by ultra high pressure liquid
chromatography-tandem mass spectrometry
(2008) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life
Sciences, 876 (1), pp. 137-142.
Holt, R.I.G., Erotokritou-Mulligan, I., Ridley, S.A., McHugh, C.M., Bassett, E.E., Cowan,
D.A., Bartlett, C., Sönksen, P.H.
A determination of the pre-analytical storage conditions for insulin like growth factor-I and
type III procollagen peptide
(2008) Growth Hormone and IGF Research, . Article in Press.
Cowan, D.A.
Drug testing.
(2008) Essays in biochemistry, 44, pp. 139-148.
Hintikka, L., Kuuranne, T., Leinonen, A., Thevis, M., Schänzer, W., Halket, J., Cowan,
D., Grosse, J., Hemmersbach, P., Nielen, M.W.F., Kostiainen, R.
Liquid chromatographic-mass spectrometric analysis of glucuronide- conjugated anabolic
steroid metabolites: Method validation and interlaboratory comparison
(2008) Journal of Mass Spectrometry, 43 (7), pp. 965-973.
Cowan, D.A., Kicman, A.T., Kubli-Garfias, C., Welchman, H.J.
Ion trap MS/MS of intact testosterone and epitestosterone conjugates-Adducts, fragile ions
and the advantages of derivatisation
(2008) Steroids, 73 (6), pp. 621-628.
Erotokritou-Mulligan, I., Bassett, E.E., Bartlett, C., Cowan, D., McHugh, C., Seah, R.,
Curtis, B., Wells, V., Harrison, K., Sönksen, P.H., Holt, R.I.G.
The effect of sports injury on insulin-like growth factor-I and type 3 procollagen:
Implications for detection of growth hormone abuse in athletes
(2008) Journal of Clinical Endocrinology and Metabolism, 93 (7), pp. 2760-2763.
McGrath, J.C., Cowan, D.A.
Drugs in sport
(2008) British Journal of Pharmacology, 154 (3), pp. 493-495.
Graham, M.R., Baker, J.S., Evans, P., Kicman, A., Cowan, D., Hullin, D., Thomas, N.,
Davies, B.
Physical effects of short-term recombinant human growth hormone administration in
abstinent steroid dependency
(2008) Hormone Research, 69 (6), pp. 343-354
Christakoudi, S., Cowan, D.A., Taylor, N.F.
Sodium ascorbate improves yield of urinary steroids during hydrolysis with Helix pomatia
juice
(2008) Steroids, 73 (3), pp. 309-319. Cited 2 times.
Drug Control Centre
Research Papers- Peer-reviewed Journals
2007
Michael R. Graham, Julien S. Baker, Peter Evans, Andrew Kicman, David Cowan, David
Hullin and Bruce Davies. Short-term recombinant human growth hormone administration
improves respiratory function in abstinent anabolic–androgenic steroid users; Growth
Hormone and IGF Research, 2007, 17, 328-335.
Graham MR, Davies B, Kicman A, Cowan D, Hullin D and Baker JS. Recombinant human
growth hormone in abstinent androgenic-anabolic steroid use: Psychological, endocrine and
trophic factor effects; Current Neurovascular Research, 2007, 4, 9-18.
Walton MJ, Anderson RA, Kicman AT, Elton RA, Ossowska K, Baird DT. A diurnal
variation in testicular hormone production is maintained following gonadotrophin
suppression in normal men. Clin Endocrinol 2007;66:123-9.
Graham MR, Baker JS, Evans P, Kicman AT, Cowan DA, Hullin D, Davis B. Evidence
for a decrease in cardiovascular risk factors following recombinant growth hormone
administration in abstinent anabolic-androgenic steroid users. Growth Horm. IGF Res
2007; Growth Hormone and IGF Research, 2007, 17, 201-209.
2006
Christiaan Bartlett, Gerard J. Clancy, David A. Cowan and James F. Healy. Detection of
the administration of human erythropoietin (HuEPO) to canines. Journal of Analytical
Toxicology, 2006, 30(9): 663-669.
Graham MR, Grace FM, Boobier W, Hullin D, Kicman A, Cowan D, et al. Homocysteine
induced cardiovascular events: a consequence of long term anabolic-androgenic steroid
(AAS) abuse. British Journal of Sports Medicine 2006;40:644-8.
Extended proceedings 2006Walker CJ, Cowan DA, Taylor NF, Kicman AT. Determination of xenobiotic
glucocorticoids by gas chromatography–mass spectrometry. In: Schanzer W, Geyer H,
Gotzmann A, Mareck U, eds. Recent Advances in Doping Analysis (14) - Proceedings of
the Manfred Donike Workshop. Koln: Sport und Buch Strauss, 2006;35-44.
Reviews 2006David A. Cowan. Drug Testing; Essays in Biochemistry, 2008, 44, 139-148
Kicman AT, Parkin MC, Iles RK. An introduction to mass spectrometry based
proteomics - Detection and characterization of gonadotropins and related molecules.
Molecular and Cellular Endocrinology 2007;260:212-27.
David Cowan. Drugs of abuse: Body fluid testing; Addiction, 2006, 101(4): 611-612.
Drug Control Centre
2006Research Papers- Peer-reviewed Journals
Graham MR, Baker JS, Evans P, Kicman AT, Cowan DA, Hullin D, Davis B.
Evidence for a decrease in cardiovascular risk factors following recombinant growth
hormone administration in abstinent anabolic-androgenic steroid users. Growth
Horm. IGF Res 2007 in press
Christiaan Bartlett, Gerard J. Clancy, David A. Cowan and James F. Healy. Detection
of the administration of human erythropoietin (HuEPO) to canines. Journal of
Analytical Toxicology, 2006, 30(9): 663-669.
Walton MJ, Anderson RA, Kicman AT, Elton RA, Ossowska K, Baird DT. A diurnal
variation in testicular hormone production is maintained following gonadotrophin
suppression in normal men. Clin Endocrinol 2007;66:123-9.
Graham MR, Grace FM, Boobier W, Hullin D, Kicman A, Cowan D, et al.
Homocysteine induced cardiovascular events: a consequence of long term anabolicandrogenic steroid (AAS) abuse. British Journal of Sports Medicine 2006;40:644-8.
Extended proceedings
Walker CJ, Cowan DA, Taylor NF, Kicman AT. Determination of xenobiotic
glucocorticoids by gas chromatography–mass spectrometry. In: Schanzer W, Geyer
H, Gotzmann A, Mareck U, eds. Recent Advances in Doping Analysis (14) Proceedings of the Manfred Donike Workshop. Koln: Sport und Buch Strauss,
2006;35-44.
Reviews
Kicman AT, Parkin MC, Iles RK. An introduction to mass spectrometry based
proteomics - Detection and characterization of gonadotropins and related molecules.
Molecular and Cellular Endocrinology 2007;260:212-27.
2001-2005
Research Papers - Peer-reviewed Journals
Cawood ML, Field HP, Ford CG, Gillingwater S, Kicman AT, Cowan D, Barth JH.
Testosterone measurements by isotope-dilution liquid chromatography-tandem mass
spectrometry: validation of a method for routine clinical practise. Clin Chem
2005;51:1472 - 1479
Malatos S, Neubert H, Kicman AT, Iles RK. Identification of placental transforming
growth factor beta and bikunin metabolites as contaminants of pharmaceutical human
chrorionic gondadotrophin preparations by proteomic techniques.
Mol Cell
Proteomics 2005;4:984-992.
Bassindale T, Cowan DA, Dale S, Leeds AR, Hutt AJ, Wheeler MJ, Kicman AT.
Effects of oral administration of androstenedione on plasma androgens in young
women using hormonal contraception. J Clin Endo Metab 2004;89: 6030-6038.
Brady BM. Walton M, Hollow N, Kicman AT, Baird DT, Anderson RA. Depot
testosterone with etonogestrel implants result in induction of azoospermia in all men
for long-term contraception. Hum Reprod 2004;19:2658-2667
Jacoby ES, Kicman AT, Iles RK. Identification of post-translational modifications
resulting from LHbeta polymorphisms by matrix-assisted laser desorption time-offlight mass spectrometric analysis of pituitary LHbeta core fragment. J Mol
Endocrinol 2003;30:239-52.
Hendrik Neubert, Kevin A. Knights, Yolanda R. de Miguel, and David A. Cowan.
MALDI TOF Post-Source Decay Investigation of Alkali Metal Adducts of Apolar
Polypentylresorcinol Dendrimers. Macromolecules, 2003, 36(22), 8297– 8303.
Kicman AT, Bassindale T, Cowan DA, Dale S, Hutt AJ, Leeds AR. Effect of
androstenedione ingestion on plasma testosterone in young women; a dietary
supplement with potential health risks. Clin Chem 2003;49:167-9 (technical brief).
Kicman AT, Fallon JK, Cowan DA, Walker C, Easmon S, Mackintosh D. Candida
albicans in urine can produce testosterone: impact on the testosterone/epitestosterone
sports drug test. Clin Chem 2002;48:1799-801 (technical brief).
Kinniburgh D, Zhu H, Cheng L, Kicman AT, Baird DT, Anderson RA. Oral
desogestrel with testosterone pellets induces consistent suppression of
spermatogenesis to azoospermia in both Caucasian and Chinese men. Hum Reprod
2002;17:1490-1501.
Forsling ML, Fallon JK, Shah D, Tilbrook GS, Cowan DA, Kicman AT, et al. The
effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its
metabolites on neurohypophysial hormone release from the isolated rat hypothalamus.
Br J Pharmacol 2002;135:649-56.
Fallon JK, Shah D, Kicman AT, Hutt AJ, Henry JA, Cowan DA, et al. Action of
MDMA (ecstasy) and its metabolites on arginine vasopressin release. Ann N Y Acad
Sci 2002;965:399-409.
Neubert H, Kicman AT, Cowan DA, Bansal SS. Synthesis of a dendron and
dendrimer consisting of MALDI matrix like branching units. Tetrahedron Letters
2002;43:6723-6727.
Neubert H, Jacoby ES, Bansal SS, Iles RK, Cowan DA, Kicman AT. Enhanced
affinity capture MALDI-TOF MS: Orientation of an immunoglobulin G using
recombinant protein G. Anal Chem 2002;74:3677-3683.
Speciation of Fe(III)-chelate complexes by electrospray ionization ion trap and laser
desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry.
Hendrik Neubert, Robert C. Hider and David A. Cowan.
Rapid Communications in Mass Spectrometry, 2002, 16, 1556-1561.
Forsling M, Fallon JK, Kicman AT, Hutt AJ, Cowan DA, Henry JA. Arginine
vasopressin
release
in
response
to
the
administration
of
3,4methylenedioxymethamphetamine ("ecstasy"): is metabolism a contributory factor? J
Pharm Pharmacol 2001;53:1357-63.
Extended Proceedings
Bassindale T, Cowan DA, Dale S, Hutt AJ, Leeds AR, Kicman AT. Disposition of
androstenedione and testosterone following oral administration of androstenedione to
healthy female volunteers; influence on the urinary T/E profile. In: Schanzer W,
Geyer H, Gotzmann A, Mareck U, eds. Recent Advances in Doping Analysis (10) Proceedings of the Manfred Donike Workshop. Koln: Sport und Buch Strauss,
2002;51-60.
Reviews
James VHT, Kicman AT (first draft authors). Medical aspects of drug use in the gym.
Drug Therap Bull. 2004;42:1-5.
Drug Abuse in Sport.
David A Cowan and Ed Houghton
in Clarke’s Analysis of Drugs and Poisons, Eds A C Moffat, M D Osselton and B
Widdop, Pharmaceutical Press, London, 2004, 134-147.
Kicman AT, Gower DB. Anabolic steroids in sport: biochemical, clinical and
analytical perspectives. Ann Clin Biochem 2003;40:321-56.
1996-2000
Research Papers - Peer-reviewed Journals
Jacoby ES, Kicman AT, Laidler P, Iles RK. Determination of the glycoforms of
human chorionic gonadotropin beta-core fragment by matrix-assisted laser
desorption/ionization time-of-flight mass spectrometry. Clin Chem 2000;46:1796803.
Kicman AT, Coutts SB, Cowan DA, Handelsman DJ, Howe CJ, Burring S, et al.
Adrenal and gonadal contributions to urinary excretion and plasma concentration of
epitestosterone in men--effect of adrenal stimulation and implications for detection of
testosterone abuse. Clin Endocrinol 1999;50:661-8.
Fallon JK, Kicman AT, Henry JA, Milligan PJ, Cowan DA, Hutt AJ. Stereospecific
analysis and enantiomeric disposition of 3, 4- methylenedioxymethamphetamine
(Ecstasy) in humans. Clin Chem 1999;45:1058-69.
Butler SA, Laidler P, Porter JR, Kicman AT, Chard T, Cowan DA, et al. The betasubunit of human chorionic gonadotrophin exists as a homodimer. J Mol Endocrinol
1999;22:185-92.
M A Popot, E Lacabaratz, P Garcia, V Laroute, Y Bonnaire, P L Toutain and D A
Cowan. New approaches to detect cortisol administration in the horse.
Equine Veterinary Journal, 1999, 31, 278-284.
Henry JA, Fallon JK, Kicman AT, Hutt AJ, Cowan DA, Forsling M. Low-dose
MDMA ("ecstasy") induces vasopressin secretion [research letter]. Lancet
1998;351:1784.
Laidler P, Cowan DA, Houghton E, Kicman AT, Marshall DE. Discrimination of
mammalian growth hormones by peptide-mass mapping. Rapid Commun Mass
Spectrom 1998;12:975-81.
Wheeler MJ, Zhong YB, Kicman AT, Coutts SB. The measurement of testosterone in
hair. J Endocrinol 1998;159:R5-8.
J.K. Fallon, A.T. Kicman, A.J. Hutt, D.A. Cowan and J.A. Henry. Enantiomeric
analysis of MDMA (Ecstasy) in plasma and urine by capillary GC: a preliminary
investigation of the stereoselective disposition in man. Journal of Pharmacy and
Pharmacology, 1998, 50 (Supplement): 117.
Kicman AT, Miell JP, Teale JD, Powrie J, Wood PJ, Laidler P, et al. Serum IGF-I and
IGF binding proteins 2 and 3 as potential markers of doping with human GH. Clin
Endocrinol (Oxf) 1997;47:43-50.
Laidler P, Cowan DA, Hider RC, Kicman AT. Characterization of human chorionic
gonadotropin microheterogeneity by capillary electrophoresis: potential application
for quality control in the pharmaceutical industry. Pharmaceutical Sciences.
1997;3:487-491.
Coutts, S. B., Kicman, A. T., Hurst, D. T. & Cowan, D. A. 1997, 'Intramuscular
administration of 5 alpha-dihydrotestosterone heptanoate: changes in urinary hormone
profile', Clin Chem, vol. 43, no. 11, pp. 2091-8.
M. A. Popot, E. Houghton, A. Ginn, M. Jones, P. Teale, T. Samuels, V Lassourd, N.
Dunnett, D.A. Cowan, Y. Bonnaire and P.L. Toutain. Cortisol concentration in post
competition horse urine: A French and British Survey. Equine Veterinary Journal,
1997, 29,226-229.
D.H. Catlin, D.A. Cowan, R. de la Torre, M. Donike, D. Fraisse, H. Oftebro, C.K.
Hatton, B. Starcevic, M. Becchi, X. de la Torre, H. Norli, H. Geyer and C.J. Walker.
Urinary testosterone (T) to epitestosterone (E) ratios by GC-MS. I. Comparison of
uncorrected T/E in six international laboratories. Journal of Mass Spectrometry,
1996, 31, 397-402.
Extended Proceedings
Approaches to the analysis of protein hormones. Discrimination of mammalian
growth hormones by peptide-mass mapping. Proceedings of the 12th International
Conference of Racing Analysts and Veterinarians. 2000; pp54-57.
S.K. Tee, G.P. Martin, A.R. Leeds, C. Walker, A. Kicman, D.A. Cowan, J. Fallon and
C. Marriott. In vitro/in vivo evaluation of the performance of two lactose carrierbased dry powder aerosol formulations for the delivery of salbutamol to the lung.
Proceedings of drug delivery to the lung XI. London, 2000, 176-179.
A D Ginn, D A Cowan and E Houghton. Approaches to the Analysis of Protein
Hormones: 1. Detection of administration of human chorionic gonadotrophin.
Proceedings of the 12th International Conference of Racing Analysts and
Veterinarians, Vancouver, Canada, 1998, 49-53.
D E Marshall, P Teale, A T Kicman, P Laidler, D A Cowan, H A Davies, R George
and E Houghton. Approaches to the Analysis of Protein Hormones: 2. Discrimination
of Mammalian Growth Hormones by Peptide-Mass Mapping. Proceedings of the 12th
International Conference of Racing Analysts and Veterinarians, Vancouver, Canada,
1998, 54-57.
M A Popot, P Garcia, L Dehennin, Y Bonnaire, V Lassourd, V Laroute, P L Toutain
and D A Cowan. ACTH Administration and Detection in the Horse. Proceedings of
the 12th International Conference of Racing Analysts and Veterinarians, Vancouver,
Canada, 1998, 131-138.
Laidler P, Cowan DA, Hider RC, Kicman AT. Qualitative analysis of hCG for
confirmatory purposes. In: Schanzer W, Geyer H, Gotzmann A, Mareck-Engelke U,
eds. Recent Advances in Doping Analysis (4) - Proceedings of the Manfred Donike
Workshop. Koln: Sport und Buch Strauss, 1997:285-304.
D A Cowan. Testing for drug abuse. The Clinical Pharmacology of Sports and
Exercise. Proceedings of the Esteve Foundation Symposium VII, Sitges, Spain, 2-5
October 1996, eds Thomas Reilly and Michael Orme, Exerpta Medica, Amsterdam,
1997, 13-20.
Sarah B. Coutts, Andrew T. Kicman, David A. Cowan. Intramuscular administration
of 5-dihydrotestosterone heptanoate: changes in the urinary hormone profile. In
Recent Advances in Doping Analysis (4), Proceedings of the Manfred Donike
Workshop 14th Cologne Workshop on Dope Analysis 17th to 22nd March 1996, eds.
W. Schänzer, H. Geyer, A. Gotzmann, U. Mareck-Engelke, Sport und Buch Strauß,
Cologne, 1997, 173-183.
M. A. Popot, V. Laroute, E. Lacabaratz, P. Garcia, P.L. Toutain and D.A. Cowan.
New Approaches to Detect Cortisol Administration: A Preliminary Study.
In Proceedings of the 11th International Conference of Racing Analysts and
Veterinarians, Queensland, Australia. Eds. D.E. Auer and E. Houghton, R and W
Publications, Newmarket, 1996, 62-67.
Reviews
Henrik Olesen, David Cowan, Rafael de la Torre, Ivan Bruunshuus, Morten Rohde
and Desmond Kenny. Properties and Units in the Clinical Laboratory Sciences. Part
XII. Properties and Units in Clinical Pharmacology and Toxicology. (Technical
Report) (IFCC-IUPAC 1999). Pure and Applied Chemistry, 2000, 72, 479-552.
Cowan DA, Laidler P. Mass Spectrometry in Drug Metabolism. Drug Metabolism:
Towards the Next Millenium, Editor N J Gooderham, IOS Press, 1998, 159-174.
David A. Cowan. Drug Abuse. Oxford Textbook of Sports Medicine. Second
Edition. Editors M. Harries, C. Williams, W D Stanish and L J Micheli, Oxford
University Press, 1998, 339-353.
D A Cowan and A T Kicman. Doping in Sport; Misuse, Analytical Tests and Legal
Aspects. Clinical Chemistry, 1997, 43, 1110-1113.
Ivan Bruunshuus, Karina Klempel, David Cowan, Gilbert Hill and Henrik Olesen.
Transmission of the results of tests for IOC defined Drugs of Abuse. J.
Chromatography B: Biomedical Applications, 1996, 687, 157-182.
David Cowan. The Misuse of Drugs in Sport. Science in Parliament, 1996, 53, No 4,
4-7.
1991-1995
Research Papers - Peer-reviewed Journals
Kicman AT, Coutts SB, Walker CJ, Cowan DA. Proposed confirmatory procedure for
detecting 5 alpha-dihydrotestosterone doping in male athletes. Clin Chem
1995;41:1617-27.
Laidler P, Cowan DA, Hider RC, Keane A, Kicman AT. Tryptic mapping of human
chorionic gonadotropin by matrix-assisted laser desorption/ionization mass
spectrometry. Rapid Commun Mass Spectrom 1995;9:1021-6.
Developing an immunoassay for the anabolic steroid stanozolol.
N.J. Barrett, A.T. Kicman, S.Bansal, D.A. Cowan.
Pharmaceutical Sciences, 1995, 1, 87-89.
Kicman AT, Cowan DA, Myhre L, Nilsson S, Tomten S, Oftebro H. Effect on sports
drug tests of ingesting meat from steroid (methenolone)-treated livestock. Clin Chem
1994;40:2084-7.
Laidler P, Cowan DA, Hider RC, Kicman AT. New decision limits and qualitycontrol material for detecting human chorionic gonadotropin misuse in sports. Clin
Chem 1994;40:1306-11.
Popot M. A., Garcia P., Bonnaire Y., Fournier F., Lassourd V. and Cowan D.A..
Study of Cortisol Metabolites Using MS Methods. In Proceedings of the 10th
International Conference of Racing Analysts and Veterinarians, Stockholm. Eds. P.
Kallings, U. Bondesson and E. Houghton, 1994, 132-135.
Kicman AT, Oftebro H, Walker C, Norman N, Cowan DA. Potential use of
ketoconazole in a dynamic endocrine test to differentiate between biological outliers
and testosterone use by athletes. Clin Chem 1993;39:1798-803.
Laidler P., Cowan D.A., Hider R.C., Kicman A.T. and O'Sullivan S.P.J..
Establishment of a new urinary threshold for use in the detection of human chorionic
gonadotropin (hCG) misuse in sport.
Journal of Pharmacy and Pharmacology
(conference proceedings), 1993, 45.
Southan GJ, Brooks RV, Cowan DA, Kicman AT, Unnadkat N, Walker CJ. Possible
indices for the detection of the administration of dihydrotestosterone to athletes. J
Steroid Biochem Mol Biol 1992;42:87-94.
Cowan D.A., Kicman A.T., Walker C.J. and Wheeler M.J. Effect of administration of
human chorionic gonadotrophin on criteria used to assess testosterone administration
in athletes. Journal of Endocrinology, 1991, 131, 147-154.
Extended Proceedings
Edited by David A. Cowan and Andrew T Kicman, 1994. Proceedings of 4th
Permanent World Congress on Doping in Sport, September 1993, Scientific Meeting,
London.
Kicman Andrew T., Coutts Sarah B., Walker Christopher J. and Cowan David A..
Detection of dihydrotestosterone administration in sport. In Proceedings of 4th
Permanent World Congress on Doping in Sport, September 1993, Scientific Meeting,
London. Edited by David A. Cowan and Andrew T Kicman, 1994, p 16-31.
Cowan David. Olympic Medication Control. In Proceedings of the Testing for
Therapeutic Medications, Environmental and Dietary Substances in Racing Horses
Workshop, Lexington, Eds. T. Tobin, G.D. Mundy, S.D. Stanley, R.A. Sams and D.L.
Crone, 1994, p 49-52.
Cowan David. In-House Thresholds for Therapeutic Medications in Olympic
Medication Testing. In Proceedings of the Testing for Therapeutic Medications,
Environmental and Dietary Substances in Racing Horses Workshop, Lexington, Eds.
T. Tobin, G.D. Mundy, S.D. Stanley, R.A. Sams and D.L. Crone, 1994, p 87-91.
Kicman A T, Cowan D A, Hider R C and Laidler P. Human chorionic gonadotropin
doping in sport: establishing a threshold limit in urine and preparation of a quality
control. Proceeding of the Association of Clinical Biochemists National Meeting,
1994, 25-26.
Cowan D.A. Doping and the rules of sport. in Proceeding of International
Symposium on Sport and Law, International Athletic Foundation, 1992, 73-74.
Catlin D., Cowan D., Donike M., Fraisse D., Oftebro H. and Rendic S. Testing urine
for drugs. Annales De Biologie Clinique, 1992, 50, 359-366.
Catlin D., Cowan D., Donike M., Fraisse D., Oftebro H. and Rendic S. Testing urine
for drugs. Journal of Automatic Chemistry, 1992, 14, 85-92.
Catlin D., Cowan D., Donike M., Fraisse D., Oftebro H. and Rendic S. Testing urine
for drugs. Clinica Chimica Acta, 1992, 207, S13-S26.
Reviews
Gower DB, Houghton E, Kicman AT. Anabolic steroids:metabolism, doping and
detection. In: Makin HLJ, Gower DB, Kirk DN, eds. Steroid analysis. First edition.
ed. Glasgow: Blackie Academic and Professional (imprint of Chapman & Hall),
1995:468--526.
Cowan DA, Kicman AT. Doping with Peptide Hormones. In: Hemmersbach P,
Birkeland KI. Blood samples in doping control. Pensumtjeneste (On Demand
Publishing). 1994:39-52.
Cowan David A.. Drug Abuse. Oxford Textbook of Sports Medicine. Editors M.
Harries, C. Williams, W D Stanish and L J Micheli, Oxford University Press, 1994,
314-329.
Cowan David A.. Drug Abuse. In ABC of Sports Medicine, Eds. Greg McLatchie,
Mark Harries, John King and Clyde Williams, BMJ, London, 1994, p 54-56.
Cowan David A. and Kicman Andrew T. Peptide Hormone Doping in Human Sports.
In Proceedings of the 10th International Conference of Racing Analysts and
Veterinarians, Stockholm. Eds. P. Kallings, U. Bondesson and E. Houghton, 1994,
195-199.
Cowan David A.. Drug Testing in Human Sports. The Biochemist, 1993, 18-22.
Catlin Don H. and Cowan David A..
Clinical Chemistry, 1992, 38, 1685-1686.
Detecting Testosterone Administration.
Kicman AT, Cowan DA. Peptide hormones and sport: misuse and detection. Br Med
Bull 1992;48:496-517.
Kicman AT, Brooks RV, Cowan DA. Human chorionic gonadotrophin and sport. Br J
Sports Med 1991;25:73-80.
.
Cowan David A. Biochemical aspects of substances banned by the IOC. Drug
Controversy in Sport. The Socio-Ethical and Medical Issues. Editors R.S. Laura and
S.W. White, Allen and Unwin, Australia. 1991, 58-79.
Cowan D.A. Use and abuse of drugs in sport. Documenta Ciba-Geigy, 1991, II.91,
6-7.
Cowan DA. Therapeutic Drugs: Monographs on anabolic steroids
Ed C Dollery. Churchill Livingstone, Edinburgh, 1991.
up to 1990
All publications
A. Ginn, E. Houghton and D.A. Cowan.Testosterone and hCG administration approaches to the problem. Proceedings of the 8th International Conference of Racing
Analysts and Veterinarians, Harare, 1990, 147-156.
Kicman AT, Brooks RV, Collyer SC, Cowan DA, Nanjee MN, Southan GJ, et al.
Criteria to indicate testosterone administration. Br J Sports Med 1990;24:253-64.
D.A. Cowan. Drugs of abuse: metabolism, analysis and clinical implications.
Screening methods. Fresenius' Journal of Analytical Chemistry, 1990, 337, 48-49.
P.Y.L. Choi, A.C. Parrott and D. Cowan. High-dose anabolic steroids in strength
athletes: effects upon hostility and aggression. Human Psychopharmacology, 1990, 5,
349-356.
P. Choi, A.C. Parrott and D.A. Cowan. Adverse behavioural effects of anabolic
steroids in athletes: a brief review. Clinical Sports Medicine, 1989, 1, 183-187.
S.L. Hart, S.C. Friend and D.A. Cowan. Alteration of w and k opioid receptor
mediated activity in mice by an anabolic steroid. Advances in the Biosciences, 1989,
75, 659-662.
D.A. Cowan, S. Ozkirimli and A.H. Beckett. The identification and determination of
some metabolites of trimipramine. Acta Pharmaceutica Suecica, 1988, 25, 141-150.
D.A. Cowan and G. Woffendin. Drug testing in human sports. Spectra, 1988, 11, 4-9.
D.A. Cowan, A. Noormohamidi and G. Woffendin
Two assays for dihydrocodeine in plasma and in urine and their use to determine the
bioavailability of a controlled release product. J. Pharm. Sci., 1988, 77, 606-609.
S.L. Hart, S.C. Friend, A. Gibson and D.A. Cowan.
The effect of an anabolic steroid and chronic exercise on nociception and plasma
corticosterone levels in rats. Proceedings of the British Pharmacological Society,
1988.
T.J. Lavelle, D.A. Cowan and L.H. Patterson. Degradation of doxorubicin by
myoglobin. Biochem. Soc. Trans., 1987, 15, 958.
D.A. Cowan. Identification of Drugs Misused in Sport. Analytical Proceedings, 1987,
24, 69-70.
D.A. Cowan, S. Friend, A. Gibson and S.L. Hart. Effect of chronic treatment with
methyltestosterone or methenolone on the sensitivity of mice to morphine. Br. J.
Pharmac., 1986, 89, 515P.
Cowan D.A., Friend S., Gibson A., Ginsburg M. and Hart S.L. Stress-inducedantinociception and morphine sensitivity in mice following chronic treatment with
anabolic/androgenic steroids. Progress in Opioid Research; Proceedings of the 1986
International Narcotics Research Conference. NIDA Research Monograph Series
#75. 1986, 343-346.
Cowan DA. Philosophy and practice of drug abuse in sport. Part II. Scientific
Considerations. Development of drugs and modern medicines. Editors J.W. Gorrod,
G.G. Gibson and M. Mitchard. Ellis Horwood, Chichester. 1986, 573-578.
Ozkirimli S, Cowan DA and Beckett AH. In-vitro metabolism of
desmethyltrimipramine to yield hydroxylamino compound. Acta Pharm. Suec., 1986,
23, 57-59
Patterson LH, Hall G, Nijjar BS, Khatra PK and Cowan DA. In-vitro metabolism of
lignocaine to its N-oxide. J. Pharm. Pharmacol. 1986, 38, 326.
Moss MS and Cowan DA. Drug abuse in sport. Clarke's Isolation and Identification
of Drugs. Senior Editor Moffat AC. The Pharmaceutical Press, London, 1986, 87100.
Cowan DA. Prescribing for sportsmen in training. British Medical Journal, 1985,
290, 298-9.
Papadopoulos AS, Crammer JL and Cowan DA. Phenolic metabolites of thioridazine
in man. Xenobiotica, 1985, 15, 309-316.
Cowan DA, Patterson LH, Damani LA and Gorrod JW. Metabolism of 4-substituted
N-ethyl-N-methylanilines: Chromatographic and mass spectrometric identification of
and N-oxidation metabolic products formed in vitro. Biomed. Mass Spectrom., 1982,
9, 233-240.
Crooks PA, Damani LA and Cowan DA. Baeyer-Villiger oxidation of metyrapone
during N-oxide formation. Chemistry and Industry, 1981, 335-336.
Damani LA, Crooks PA and Cowan DA. Metabolism of metyrapone. 2.
Chromatographic and mass spectral properties of the N-oxides of metyrapone and
metyrapol. Biomed. Mass Spectrom., 1981, 8, 270-277.
Damani LA, Crooks PA and Cowan DA. Metabolism of Metyrapone.3. Formation of
an Alpha-Pyridone Metabolite by Rat Hepatic Soluble Enzymes. Drug Metab.
Disposition, 1981, 9, 270-273.
Crooks PA, Damani LA and Cowan DA. Synthesis of N-oxide derivatives of
metyrapone and their detection as in vitro metabolites. Journal of Pharmacy and
Pharmacology, 1981, 33, 309-312.
Cowan DA. Gas chromatographic analysis of drugs abused in sport. Doping Control
of Athletes, ed. Rogozkin VA and Litvinova VN, Soyuzsportobespechenie, Moscow,
1980, 83-95.
Gorrod JW, Bryan J, Cowan DA and Damani LA. The in vitro metabolism of 3acetylpyridine, 3-acetylpyridine-N-oxide and 1-(3-pyridyl)ethanol. Microsomes,
Drug Oxidations and Chemical Carcinogenesis, Vol. 2, ed. Coon MJ, Conney AH,.
Estabrook RW, Gelboin HV, Gillette JR and O'Brien PJ, Academic Press, New York,
1980, 961-964.
Damani LA, Bryan J, Cowan DA and Gorrod JW. The origin of 1-(3-pyridyl-Noxide)ethanol as a metabolite of 3-acetylpyridine. Xenobiotica, 1980, 10, 645-653.
Beckett AH and Cowan DA. Misuse of Drugs in Sport. British Journal of Sports
Medicine, 1979, 12, 185-194.
Cowan DA. Mass Spectrometry as an aid to the Identification of N-oxygenated
Organic Molecules. Biological Oxidation of Nitrogen, ed. J.W. Gorrod,
Elsevier/North Holland Biomedical Press, 1978, 263-268.
Cowan DA, Damani LA and Gorrod JW. Metabolic N-oxidation of 3-substituted
pyridines: Identification of Products by Mass Spectrometry. Biomedical Mass
Spectrometry, 1978, 5, 551-556.
Beckett AH and Cowan DA. Pitfalls in drug metabolism methodology. Drug
Metabolism in Man, Taylor Francis, London, 1978, 237-257.
Cowan DA. Gas Chromatography. Annual Reports B, The Chemical Society,
London, 1976, 68, 11-22.
Cowan DA, Huizing G, Beckett AH. Identification of four new metabolic products of
metoclopramide using mass spectrometry. Xenobiotica, 1976, 6, 605-616.
Cowan DA. Problems in the analysis of N-oxygenated products of the
phenothiazines. Methodological Developments in Biochemistry, Vol. 5: Assay of
Drugs and other Trace Compounds in Biological Fluids, ed. E. Reid, ASP Biological
and Medical Press, Amsterdam, 1976.
Essien EE, Cowan DA and Beckett AH. Metabolism of Phenothiazines:
Identification of N-oxygenated products by gas chromatography and mass
spectrometry. Journal of Pharmacy and Pharmacology, 1975, 27, 334-342.
Beckett AH and Cowan DA. The dissolution rate of digoxin tablets on the U.K.
market: the scale of the problem. Postgraduate Medical Journal, 1974, 50 (Suppl. 6),
52-55.
Beckett AH and Cowan DA. Differences in the dissolution rate of generic digoxin
tablets. Pharm. J., 1973, 111-112.