Download Molecular Mechanisms in Biology BMSC-GA 2004 Fall 2015

Molecular Mechanisms in Biology
BMSC-GA 2004
Fall 2015
The goal of this course is to provide an in-depth understanding of the molecular mechanisms underlying
key biological processes by examining the structure and mechanism of the macromolecules that govern
those processes.
4 credit hours
Lectures on Mon. and Wed., 10:30-12:00. Discussion session on Fri., 10:30-12:00.
First class on Mon., Sept. 14th.
Course director: Dr. Stevan Hubbard – Skirball 3rd floor, lab 14; 263-8938;
[email protected]
Suitable for 1st- or 2nd-year students
Topics
• Principles of protein structure and folding
• Enzyme structure and mechanism
• Structure-based drug design
• Molecular machines
• Membrane proteins
• Chromatin structure and epigenetics
• Protein-nucleic acid recognition
• RNA structure, ribozymes and riboswitches
• Ligand-receptor recognition
• Protein-protein interactions in signal transduction
• Protein-protein interactions in immune recognition
• Introduction to x-ray crystallography and electron microcopy
Instructors
• Dr. Karim-Jean Armache
• Dr. Joel Belasco
• Dr. Stevan Hubbard
• Dr. Xiangpeng Kong
• Dr. Michelle Krogsgaard
• Dr. Moosa Mohammadi
• Dr. Alexander Serganov
• Dr. David Stokes
• Dr. Da-Neng Wang