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Secondary Prevention Basis for Secondary Prevention • • • • • • STDs Drug Resistance HIV super-infection Mother to child transmission Hepatitis C Hepatitis B Condoms Protect ? • 98.5% risk reduction /single act with infected partner – 14% failure with 10 acts – 26% failure for 20 acts – 37% failure for 30 acts Fitch STD 2002, Mann STD 2002 Condoms are not Perfect • Slippage – 0.8% (5y experience) • Breakage – 0.7% (5y experience) • Pregnancy Risk – 6% (< 2 y experience) – 3.6% (>4y experience) Messiah AJPH 1997 Sexual Behavior Risk Fisher and Fisher, Options Project • 51% of HIV+ clinic participants engaged in sexual activity in pat 3 mos. • 52/496 HIV + participants had risky vaginal or anal sex with 197 partners in past 3 mos. Drug Use Risk Fisher and Fisher, Options Project • 35% of IDUs who injected in last month borrowed or lent dirty works to: – 75 HIV – – 113 HIV unknown – 65 HIV + Sexual Risk • 50-90% HIV+ remain sexually active after diagnosis • 20-60% HIV + and sexually active don’t use condoms consistently Darrow et. al 1998, Wilson 1999, Deren 1998, Fisher, 1999, Interventions to Reduce Sexual Risk Behaviors • Population – HIV + Drug users – Women – HIV + MSM • Increased Condom use • Decreased sexual partners 26% decrease in unprotected sex • Risk Reduction – 0.81 (OR) – 50% risk reduction at 6mos – 0.69 (OR) • 0.61(OR) • 0.74 (OR) Shain STD 2002, Semaan JAIDS 2002, Johnson JAIDS 2002 Mentally Ill • Cognitive-behavioral HIV risk reduction – Increased condom use – Higher percentage of intercourse occasions with condoms – More positive attitudes toward condoms – Behavior change present at 3,6,9 mos. – Behavior change diminished by 12 mos. Otto-Salag Com Mental Health J 2001 Types of interventions • Social • Structural • Behavioral – Motivational Interviewing – Counseling • Education – Risk reduction – Risk consequences Approaches to Harm Reduction • • • • • • Multiple attempts Longitudinal follow up Patient buy-in Multidisciplinary Consistent messages Non judgmental