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Tuberculosis in the EU: An ECDC perspective World TB day European Parliament 22 March 2007 Zsuzsanna Jakab ECDC Director The issues... • Public health • Socio-economical • Scientific • Regional Regional gradient in TB cases, Europe 2005 Cases per 100,000 population Not included No data 0 – 10 11 – 20 21 – 50 >50 FSU 110/100,000 EU-27 19/100,000 Balkan states 29/100,000 Source: EuroTB TB trends in Europe, 1995-2005 Cases per 100,000 population 120 100 FSU (exc. Baltic) 80 Europe-53 60 Balkans 40 EU-27 20 EU-25 0 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 Source: EuroTB Migration patterns change the epidemiology of TB TB cases of foreign origin, Europe 2005 Percentage cases foreign origin No data 0%–4% 5 % – 19 % 20 % – 49 % >49 % 19% EU cases of foreign origin Source: EuroTB TB/HIV co infection in the EU, 2000-2005* Percentage cases with HIV 18 16 14 12 10 8 6 United Kingdom 4 2 0 2000 2001 Portugal Spain Estonia Latvia 2002 2003 2004 2005 * countries with >50 TB cases/year and with data for > two years Source: EuroTB TB in vulnerable populations in a low incidence country 400 Rate/100,000 370 217 Highest rate in Europe (KAZ) 104 FSU 174 94 14 EU 0 18 32 Country City average aver. 33 Eld. Foreign Inner Prisons 74+ males city Data 2003, Sources: BES. Agencia Salut Publica Barcelona. Dirección General IIPP Scientific issue • • • Vaccine does not reduce transmission • Operational research needed New drugs and diagnostic methods needed Drug resistance (MDR and XDR) an obstacle for successful treatment Multi drug resistance (MDR), EU 2005 Percentage per tested cases Latvia Cyprus Romania Hungary* Spain* Bulgaria* Italy* Germany Slovakia Austria Portugal* Ireland* Czech Republic* Greece* France Denmark Belgium Finland United Kingdom Slovenia Netherlands Malta* Luxembourg 0 5 10 15 Estonia Lithuania 20 25 * Countries with incomplete data Source: EuroTB TB challenges for the EU TB PATTERN CHALLENGES Move towards elimination Low incidence EU, 20 countries Moderate to high incidence EU, 7 countries High incidence neighbouring countries TB increasingly rare Vulnerable groups Containing outbreaks Maintain awareness and expertise Population-level control HIV Drug resistance (MDR, XDR) Collaboration with neighbouring countries ECDC strategies for TB in 2007 • • • • Further strengthen surveillance Strengthen laboratory capacity Develop scientific guidance Analyse national action plans with countries to further sterngthen them • Develop European Action Plan at request of Commissioner Kyprianou Conclusions • TB remains an issue of concern for all countries • Strategies to be developed according to the epidemiological situation • Pursue effective partnership • Progress towards elimination only achievable if the global burden of TB decreases Thank you! [email protected] Zsuzsanna Jakab Director, ECDC ecdc.europa.eu