Download PREPRATION OF ASPIRIN

PREPRATION OF ASPIRIN
The aim of the experiment is
synthesize on of common
pain relievers aspirin, To
determine the punty of the
aspirin.
Why you esterfication
salicylic acid ?

Procedure:1- weigh out 2.0 g of salicylic acid . place it in a125ml erlenmeger flask.
2-Add 5 ml of acetic anhydride swirl the flask to wet
the salicylic acid crystals.
3- Add 5 drops of can centrated sulfuric acid , h2
so4 , to the mixture
4-Gently heat the flask in aboiling water both ofr
about 10 minutes .
5- Remove the flask from the hot water both and add
110 ml of deionized ice water to decompose
any exess any excess acetic anhydride
6- Chill the solution in an ice bath until crystals of
Aspirin no longer form, stiring occasionally to
decompose residual acetic anhydride. If (oil)
Appears instead of a solid, reheat the flask in the hot
water bath until the oil disappears and again cool.
7-Filter the liquid under vacuum and wash with 15
ml of cold water.
Are you use this Aspirin as a drug ?
Why?
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