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Transcript
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Resident’s Name, Degree(s) with periods [eg. B.Sc.(Pharm).]; Other investigators’ names [no “Dr.’s”], Degree(s) with periods. NO AFFILIATIONS.
Background
Results
 Clinical pharmacists frequently base treatment
recommendations on the primary literature.
 Recalling specific details about clinical trials is often important,
though sometimes difficult.
 Processes to provide very rapid access to the original trial data
are needed.
 A standalone PalmOS-based software application was developed using
PDA Toolbox version 4.2 for Windows.
 The application allows clinicians to enter critical data and notes from clinical
trials related to their individual practice and quickly retrieve them.
 The software automatically calculates effect sizes based on absolute
incidences entered (e.g.. RRR, RR, ARR, NNT/NNH).
 Clinical pharmacists frequently base treatment
recommendations on the primary literature.
 Recalling specific details about clinical trials is often important,
though sometimes difficult.
 Processes to provide very rapid access to the original trial data
are needed.
 Clinical pharmacists frequently base treatment
recommendations on the primary literature.
 Recalling specific details about clinical trials is often important,
though sometimes difficult.
 Processes to provide very rapid access to the original trial data
are needed.
 The software also allows entry of an individual patient’s perceived baseline
risk (e.g.. based on the clinician’s suspicion or another risk estimation
scheme) and applies the trial’s effect to it, allowing individualized estimates
of the magnitude/likelihood of efficacy or harm based on the trial data.
Table 1: Trial details can be reviewed to determine applicability
to the current clinical scenario.
 The software allows the user to add “notes” to a trial where their own
interpretation and comments about the trial can be stored.
 The program is comprised of three files: A program (.prc) file (51KB) and
two database (.pdb) files (total size ~40KB, but dependent on amount of
data entered).
 A standalone PalmOS-based software application was developed using
PDA Toolbox version 4.2 for Windows.
 The application allows clinicians to enter critical data and notes from clinical
trials related to their individual practice and quickly retrieve them.
Methods
 Although a database of over 950 PDF versions of clinical
papers was maintained by the author and available from any
PC in the hospital, even more rapid access to trial data while on
rounds, teaching, evaluating patients, or outside the hospital
was needed.
 A précis of the critical trial data in a portable form, including a
method to estimate an individual patient’s chances of
benefiting or being harmed by a particular therapy was desired.
Although a database of over 950 PDF versions of clinical
papers was maintained by the author and available from any
PC in the hospital, even more rapid access to trial data while on
rounds, teaching, evaluating patients, or outside the hospital
was needed.
 A précis of the critical trial data in a portable form, including a
method to estimate an individual patient’s chances of
benefiting or being harmed by a particular therapy was desired.
AVOID 3D GRAPHICS! Keep it clean
and simple… few horizontal lines on
graphs, no background colors.
Table 2: Details of the specific trial endpoint, in a number of formats.
Figure 1: Details of the specific trial endpoint, in a number of
formats.
Poster template notes: This is a 36 inch
high (the max) by 48 inch long poster.
Suggest NOT adjusting either of these
unless absolutely necessary. If necessary,
the length can be increased to a MAX of
56”. Each square foot costs $10.25.
Conclusions
 It is feasible to create a handheld tool for storing, retrieving and interpreting
clinical trial data.
 Such a tool can be used at the “point of curiosity” to improve the quality of
clinical decision-making related to drug therapy.
 The tool is also useful for informing patients about their individualized
expected benefits or risks of drug therapy, thus as an aid to “evidencebased patient choice”.
“Limitations” Box is a reasonable idea.
“References” box is optional.