Male lower urinary tract symptoms (LUTS)
... Despite meticulous methodology and attention to detail there are areas of uncertainty where no controlled trials (RCT) of sufficient quality exist. In such situations we took account of what is currently perceived to be best practice, potential adverse events and the patients’ perception in the inte ...
... Despite meticulous methodology and attention to detail there are areas of uncertainty where no controlled trials (RCT) of sufficient quality exist. In such situations we took account of what is currently perceived to be best practice, potential adverse events and the patients’ perception in the inte ...
COMMITTEE ON FINANCE UNITED STATES SENATE CHARLES E
... questions about the FDA’s decision to approve that device for the treatment of TRD. While all implantable medical devices carry risks, it is questionable whether or not the VNS Therapy System for TRD met the agency’s standard for safety and effectiveness. The FDA’s approval process requires a compre ...
... questions about the FDA’s decision to approve that device for the treatment of TRD. While all implantable medical devices carry risks, it is questionable whether or not the VNS Therapy System for TRD met the agency’s standard for safety and effectiveness. The FDA’s approval process requires a compre ...
ROBERT M. CALIFF PAGE 1 of 114
... Washington, DC, Drug Forum Workshop on IOM Drug Safety Report, presentation, “Funding large research studies” Washington, DC, CERTs PATHs Committee Meeting, presentation, “The future of drug safety and Research Gaps” Rockville, MD, DES Thrombosis Think Tank Mtg, presentation, “Safety, DES, and DAP T ...
... Washington, DC, Drug Forum Workshop on IOM Drug Safety Report, presentation, “Funding large research studies” Washington, DC, CERTs PATHs Committee Meeting, presentation, “The future of drug safety and Research Gaps” Rockville, MD, DES Thrombosis Think Tank Mtg, presentation, “Safety, DES, and DAP T ...
http://www.cadth.ca/media/pdf/TR0004_RRMS_ScienceReport_e.pdf
... The information in this report is intended to help Canadian health care decision-makers, health care professionals, health systems leaders, and policy-makers make well-informed decisions and thereby improve the quality of health care services. The information in this report should not be used as a s ...
... The information in this report is intended to help Canadian health care decision-makers, health care professionals, health systems leaders, and policy-makers make well-informed decisions and thereby improve the quality of health care services. The information in this report should not be used as a s ...
Sedation in children and young people
... safely”. In other words, it became clear that the problem was less “What drugs?” but more “Who can administer them?”. Indeed, if it can be agreed that a chosen drug technique is effective, people need to know who can use it safely. In consequence we have had two broad aims. Our first was to review t ...
... safely”. In other words, it became clear that the problem was less “What drugs?” but more “Who can administer them?”. Indeed, if it can be agreed that a chosen drug technique is effective, people need to know who can use it safely. In consequence we have had two broad aims. Our first was to review t ...
Treatment for Glaucoma: Comparative Effectiveness Comparative Effectiveness Review Number 60
... than the class of nonpenetrating procedures. As expected, incisional surgeries produce more significant side effects than do medical treatments. Conclusions. We did not find evidence addressing direct or indirect links between glaucoma treatment and visual impairment or patient-reported outcomes. Th ...
... than the class of nonpenetrating procedures. As expected, incisional surgeries produce more significant side effects than do medical treatments. Conclusions. We did not find evidence addressing direct or indirect links between glaucoma treatment and visual impairment or patient-reported outcomes. Th ...
Second-Generation Antidepressants in the Pharmacologic Treatment of Adult
... Evidence Reports/Technology Assessments to assist public- and private-sector organizations in their efforts to improve the quality of health care. The EPCs now lend their expertise to the Effective Health Care Program by conducting comparative effectiveness reviews (CERs) of medications, devices, an ...
... Evidence Reports/Technology Assessments to assist public- and private-sector organizations in their efforts to improve the quality of health care. The EPCs now lend their expertise to the Effective Health Care Program by conducting comparative effectiveness reviews (CERs) of medications, devices, an ...
Theophylline
... studies, reviews, metaanalyses and Cochrane reviews. Especially the pharmacokinetic studies are valuable and demonstrate important aspects of the developmental changes in the pharmacokinetic parameters during the various stages in childhood, whereas the clinical studies add less to the knowledge of ...
... studies, reviews, metaanalyses and Cochrane reviews. Especially the pharmacokinetic studies are valuable and demonstrate important aspects of the developmental changes in the pharmacokinetic parameters during the various stages in childhood, whereas the clinical studies add less to the knowledge of ...
SEVOFLURANE
... Sevoflurane is contraindicated in patients in whom liver dysfunction, jaundice, or unexplained fever, leucocytosis, or eosinophilia has occurred after a previous halogenated anesthetic administration. See WARNINGS AND PRECAUTIONS, ...
... Sevoflurane is contraindicated in patients in whom liver dysfunction, jaundice, or unexplained fever, leucocytosis, or eosinophilia has occurred after a previous halogenated anesthetic administration. See WARNINGS AND PRECAUTIONS, ...
Allergic Rhinitis and its Impact on Asthma (ARIA)
... R.GvW. received fees for lectures and expert panel participation from Allmiral, Alcon, Hal, Merck Sharp & Dome, Novartis, Stallargènes and UCB. H.J.S. is co-chair of the GRADE working group and he supports the implementation of the GRADE approach worldwide. From non-profit organizations he has accep ...
... R.GvW. received fees for lectures and expert panel participation from Allmiral, Alcon, Hal, Merck Sharp & Dome, Novartis, Stallargènes and UCB. H.J.S. is co-chair of the GRADE working group and he supports the implementation of the GRADE approach worldwide. From non-profit organizations he has accep ...
Determinants and Correlates of Placebo
... Placebo:.................................................................................................................................................................... 6 True/Pure Placebo: .......................................................................................................... ...
... Placebo:.................................................................................................................................................................... 6 True/Pure Placebo: .......................................................................................................... ...
Stenting of Bifurcation Lesions
... however, in parallel, it also serves to highlight the safety concerns associated with their use, which have predominantly centered around stent thrombosis (ST) (1–3). The cause of ST is clearly multifactorial, and in addition to patient and lesion factors, a portion of blame has been attributed to t ...
... however, in parallel, it also serves to highlight the safety concerns associated with their use, which have predominantly centered around stent thrombosis (ST) (1–3). The cause of ST is clearly multifactorial, and in addition to patient and lesion factors, a portion of blame has been attributed to t ...
- BioMed Central
... A comparative study on the efficacy of albendazole and mebendazole in the treatment of ascariasis, hookworm infection and trichuriasis. Southeast Asian J Trop Med Public Health. 1993 Dec;24(4):724-9. PMID: 7939948 [PubMed - indexed for MEDLINE] ...
... A comparative study on the efficacy of albendazole and mebendazole in the treatment of ascariasis, hookworm infection and trichuriasis. Southeast Asian J Trop Med Public Health. 1993 Dec;24(4):724-9. PMID: 7939948 [PubMed - indexed for MEDLINE] ...
PRODUCT MONOGRAPH Pr CLINDOXYL® ADV Gel Pr
... Pregnant Women: There are no well-controlled studies in pregnant women treated with topical CLINDOXYL® Gel or CLINDOXYL® ADV Gel. There are limited data on the use of topical clindamycin or benzoyl peroxide in pregnant women. CLINDOXYL® Gel or CLINDOXYL® ADV Gel should not be administered to a pregn ...
... Pregnant Women: There are no well-controlled studies in pregnant women treated with topical CLINDOXYL® Gel or CLINDOXYL® ADV Gel. There are limited data on the use of topical clindamycin or benzoyl peroxide in pregnant women. CLINDOXYL® Gel or CLINDOXYL® ADV Gel should not be administered to a pregn ...
Extract from the Clinical Evaluation Report for Sofosbuvir
... The TGA administers the Therapeutic Goods Act 1989 (the Act), applying a risk management approach designed to ensure therapeutic goods supplied in Australia meet acceptable standards of quality, safety and efficacy (performance), when necessary. ...
... The TGA administers the Therapeutic Goods Act 1989 (the Act), applying a risk management approach designed to ensure therapeutic goods supplied in Australia meet acceptable standards of quality, safety and efficacy (performance), when necessary. ...
Osteoarthritis — Care and management in adults
... Healthcare professionals are expected to take NICE clinical guidelines fully into account when exercising their clinical judgement. However, the guidance does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of each patient, in consultati ...
... Healthcare professionals are expected to take NICE clinical guidelines fully into account when exercising their clinical judgement. However, the guidance does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of each patient, in consultati ...
Extract from the Clinical Evaluation Report for Sofosbuvir
... First round benefit-risk assessment ______________________________ 73 8.1. First round assessment of benefits _________________________________________ 73 8.2. First round assessment of risks _____________________________________________ 74 8.3. First round assessment of benefit-risk balance _______ ...
... First round benefit-risk assessment ______________________________ 73 8.1. First round assessment of benefits _________________________________________ 73 8.2. First round assessment of risks _____________________________________________ 74 8.3. First round assessment of benefit-risk balance _______ ...
Full text - Nasjonalt kunnskapssenter for helsetjenesten
... The Norwegian Knowledge Centre for the Health Services was commissioned by the Health Directorate to conduct a systematic literature search with subsequent sorting of possible relevant publications. The aim was to identify systematic reviews on the effect of interventions designed to improve patient ...
... The Norwegian Knowledge Centre for the Health Services was commissioned by the Health Directorate to conduct a systematic literature search with subsequent sorting of possible relevant publications. The aim was to identify systematic reviews on the effect of interventions designed to improve patient ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights
... Persons who are using drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in susceptible children or adults using corticosteroids. In such children or adults who have not ...
... Persons who are using drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in susceptible children or adults using corticosteroids. In such children or adults who have not ...
The effectiveness and cost-effectiveness of dual-chamber pacemakers compared with single-chamber pacemakers for
... The HTA Programme was set up in 1993. Its role is to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS. ‘Health technologies’ are broadly defi ...
... The HTA Programme was set up in 1993. Its role is to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS. ‘Health technologies’ are broadly defi ...
Atrial fibrillation: the management of atrial fibrillation
... prevalence is increasing. If left untreated atrial fibrillation is a significant risk factor for stroke and other morbidities. Men are more commonly affected than women and the prevalence increases with age. The aim of treatment is to prevent complications, particularly stroke, and alleviate symptom ...
... prevalence is increasing. If left untreated atrial fibrillation is a significant risk factor for stroke and other morbidities. Men are more commonly affected than women and the prevalence increases with age. The aim of treatment is to prevent complications, particularly stroke, and alleviate symptom ...
Médicaments antiviraux en cas de grippe saisonnière et pandémique. recommandations de bonne
... Univ. Saint-Luc, Brussels), Maes Sophie (Institute of Public Health, Brussels) ...
... Univ. Saint-Luc, Brussels), Maes Sophie (Institute of Public Health, Brussels) ...
Advair HFA - GSK Source
... rate of asthma-related death occurred in subjects treated with salmeterol than those treated with placebo (0.10% versus 0.02%; relative risk: 4.37 [95% CI: 1.25, 15.34]). Post-hoc subpopulation analyses were performed. In Caucasians, asthma-related death occurred at a higher rate in subjects treated ...
... rate of asthma-related death occurred in subjects treated with salmeterol than those treated with placebo (0.10% versus 0.02%; relative risk: 4.37 [95% CI: 1.25, 15.34]). Post-hoc subpopulation analyses were performed. In Caucasians, asthma-related death occurred at a higher rate in subjects treated ...
Lupron SUQS: Serious Unanswered QuestionS
... 54. Since healthcare workers (according to NIH/OSHA guidelines) handle hazardous drugs with protective gear (and lupron/leuprolide is on the “Hazardous Drug” list), why are they advised to “avoid contact” with lupron/leuprolide for “a specific time period (e.g.., 3 months)” if the worker is “trying ...
... 54. Since healthcare workers (according to NIH/OSHA guidelines) handle hazardous drugs with protective gear (and lupron/leuprolide is on the “Hazardous Drug” list), why are they advised to “avoid contact” with lupron/leuprolide for “a specific time period (e.g.., 3 months)” if the worker is “trying ...