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TRIGGERFISH
Glaucoma Monitoring System
BME 181
Brittany M. Alphonse Biomedical Engineering
Table of Contents
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Glaucoma
Current Glaucoma
Monitoring Systems
Triggerfish Glaucoma
Monitoring System
Triggerfish System
Components
Benefits
Glaucoma
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Progressive and Irreversible Disease
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leads to blindness
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fluid accumulates in eye
high levels of liquid inside eye
Diameter of cornea changes
Deterioration of Optic Nerve
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Asymptomatic
Contributor of disease:
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frequent changes in pressure over the span of a day
high peaks in levels during night
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40+ years of age
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4% of population is affected
Current Glaucoma Monitoring Systems
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Measures static intraocular pressure
Single Snapshots in Time
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Monitoring in Overnight Sleep Labs
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taken during the day when pressure is lowest
cumbersome
expensive
Frequent Punctual Measurements
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affects intraocular pressure
checks pressure peaks
Triggerfish System
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Created by SENSIMED
First of its Kind on the
market
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constant reading device
Safety Approval in
Europe last year
Expected U.S. Food and
Drug Administration
Approval in late 2011
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Non-Invasive Continuous
Monitoring System
Measures Intraocular
Pressure up to 24 hours
Does Not Interfere with
Normal Vision
Constant Reading for
Fraction of Price
Triggerfish System Components
Sensor and Processor
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Disposable Contact Lens
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MEMS Sensor
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soft
hydrophilic
silicone
sensor and microprocessor on
outer edge
strain gauge monitors diameter
change in cornea
Telemetry Microprocessor
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Processes level changes
transmits to receiver
Components Continued
Antenna
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Circular Antenna
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taped around the eye
Sends Energy to Sensor
Receives Measurement
Information
Connected to Portable
Recorder
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thin flexible data cable
Components Continued
Recorder/ Receiver
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Battery Powered
Stores Measured
Information
Wirelessly Uploads
Information
Worn Around Neck
Software
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Ophthalmologist
Receives Information
Visualize Intraocular
Pressure Profile
Benefits of Triggerfish System
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Improved Understanding of Pressure Change
 pressure
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during day versus night
More Efficient
Personalized Drug Delivery and Treatment
Adapt Treatment
 dependent
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on changing conditions
Sensor is Placed Outside of Vision Field
Early Diagnosis and Treatment
References for Pictures
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http://www.sensimed.ch/S-Trig-benefits.htm
http://www.technologyreview.com/business/24931
/page1/
http://www.sensimed.ch/S-Trig-solution.htm